Zinc in PDB 7ukh: Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region

The structure of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region also contains other interesting chemical elements:

Calcium

(Ca)

12 atoms

The binding sites of Zinc atom in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region (pdb code 7ukh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region, PDB code: 7ukh:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn901 b:26.1 occ:1.00 ND1 A:HIS105 2.1 10.2 1.0 SG A:CYS133 2.3 17.6 1.0 SG A:CYS132 2.3 20.3 1.0 SG B:CYS111 2.4 12.6 1.0 CE1 A:HIS105 2.8 10.2 1.0 CB B:CYS111 3.1 12.6 1.0 CB A:CYS132 3.1 20.3 1.0 CG A:HIS105 3.2 10.2 1.0 CB A:CYS133 3.7 17.6 1.0 CB A:HIS105 3.8 10.2 1.0 N A:CYS133 3.8 17.6 1.0 C A:CYS132 4.0 20.3 1.0 NE2 A:HIS105 4.0 10.2 1.0 CA A:CYS132 4.1 20.3 1.0 CA A:HIS105 4.2 10.2 1.0 CD2 A:HIS105 4.2 10.2 1.0 CA A:CYS133 4.3 17.6 1.0 O A:CYS132 4.5 20.3 1.0 CA B:CYS111 4.5 12.6 1.0 CB B:SER113 4.7 10.2 1.0 NZ A:LYS103 4.7 15.8 1.0 N A:CYS132 4.8 20.3 1.0 O A:LEU104 5.0 11.5 1.0

Zinc binding site 2 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn901 b:27.1 occ:1.00 ND1 B:HIS105 2.1 10.2 1.0 SG B:CYS133 2.3 17.3 1.0 SG B:CYS132 2.3 20.5 1.0 SG C:CYS111 2.3 12.6 1.0 CE1 B:HIS105 2.8 10.2 1.0 CB C:CYS111 3.1 12.6 1.0 CB B:CYS132 3.1 20.5 1.0 CG B:HIS105 3.2 10.2 1.0 CB B:CYS133 3.7 17.3 1.0 CB B:HIS105 3.8 10.2 1.0 N B:CYS133 3.8 17.3 1.0 C B:CYS132 4.0 20.5 1.0 NE2 B:HIS105 4.0 10.2 1.0 CA B:CYS132 4.1 20.5 1.0 CA B:HIS105 4.2 10.2 1.0 CD2 B:HIS105 4.2 10.2 1.0 CA B:CYS133 4.3 17.3 1.0 O B:CYS132 4.5 20.5 1.0 CA C:CYS111 4.5 12.6 1.0 CB C:SER113 4.6 10.2 1.0 NZ B:LYS103 4.7 16.1 1.0 N B:CYS132 4.8 20.5 1.0 O B:LEU104 5.0 11.3 1.0

Zinc binding site 3 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn901 b:27.5 occ:1.00 ND1 C:HIS105 2.1 10.0 1.0 SG D:CYS111 2.3 12.9 1.0 SG C:CYS133 2.3 17.1 1.0 SG C:CYS132 2.3 20.2 1.0 CE1 C:HIS105 2.8 10.0 1.0 CB D:CYS111 3.1 12.9 1.0 CB C:CYS132 3.1 20.2 1.0 CG C:HIS105 3.2 10.0 1.0 CB C:CYS133 3.7 17.1 1.0 CB C:HIS105 3.8 10.0 1.0 N C:CYS133 3.8 17.1 1.0 C C:CYS132 4.0 20.2 1.0 NE2 C:HIS105 4.0 10.0 1.0 CA C:CYS132 4.1 20.2 1.0 CA C:HIS105 4.2 10.0 1.0 CD2 C:HIS105 4.2 10.0 1.0 CA C:CYS133 4.3 17.1 1.0 CA D:CYS111 4.5 12.9 1.0 O C:CYS132 4.5 20.2 1.0 CB D:SER113 4.6 10.3 1.0 NZ C:LYS103 4.7 15.8 1.0 N C:CYS132 4.8 20.2 1.0 O C:LEU104 5.0 11.2 1.0 N D:ALA114 5.0 8.2 1.0

Zinc binding site 4 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn901 b:26.8 occ:1.00 ND1 D:HIS105 2.1 10.3 1.0 SG A:CYS111 2.2 13.0 1.0 SG D:CYS133 2.3 17.5 1.0 SG D:CYS132 2.3 20.5 1.0 CE1 D:HIS105 2.8 10.3 1.0 CB A:CYS111 3.0 13.0 1.0 CB D:CYS132 3.1 20.5 1.0 CG D:HIS105 3.2 10.3 1.0 CB D:CYS133 3.7 17.5 1.0 CB D:HIS105 3.8 10.3 1.0 N D:CYS133 3.8 17.5 1.0 C D:CYS132 4.0 20.5 1.0 NE2 D:HIS105 4.0 10.3 1.0 CA D:CYS132 4.1 20.5 1.0 CA D:HIS105 4.2 10.3 1.0 CD2 D:HIS105 4.2 10.3 1.0 CA D:CYS133 4.3 17.5 1.0 CA A:CYS111 4.4 13.0 1.0 O D:CYS132 4.5 20.5 1.0 CB A:SER113 4.6 10.6 1.0 NZ D:LYS103 4.7 16.2 1.0 N D:CYS132 4.8 20.5 1.0 N A:ALA114 5.0 8.3 1.0 O D:LEU104 5.0 11.3 1.0

W.Ye, H.Zhao, Y.Dai, Y.Wang, Y.H.Lo, L.Y.Jan, C.H.Lee. Activation and Closed-State Inactivation Mechanisms of the Human Voltage-Gated K V 4 Channel Complexes. Mol.Cell V. 82 2427 2022.
ISSN: ISSN 1097-2765
PubMed: 35597238
DOI: 10.1016/J.MOLCEL.2022.04.032