Zinc in PDB 7ukh: Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region

Other elements in 7ukh:

The structure of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region also contains other interesting chemical elements:

Calcium (Ca) 12 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region (pdb code 7ukh). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region, PDB code: 7ukh:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 7ukh

Go back to Zinc Binding Sites List in 7ukh
Zinc binding site 1 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn901

b:26.1
occ:1.00
 ND1 A:HIS105 2.1 10.2 1.0
SG A:CYS133 2.3 17.6 1.0
SG A:CYS132 2.3 20.3 1.0
SG B:CYS111 2.4 12.6 1.0
CE1 A:HIS105 2.8 10.2 1.0
CB B:CYS111 3.1 12.6 1.0
CB A:CYS132 3.1 20.3 1.0
CG A:HIS105 3.2 10.2 1.0
CB A:CYS133 3.7 17.6 1.0
CB A:HIS105 3.8 10.2 1.0
N A:CYS133 3.8 17.6 1.0
C A:CYS132 4.0 20.3 1.0
NE2 A:HIS105 4.0 10.2 1.0
CA A:CYS132 4.1 20.3 1.0
CA A:HIS105 4.2 10.2 1.0
CD2 A:HIS105 4.2 10.2 1.0
CA A:CYS133 4.3 17.6 1.0
O A:CYS132 4.5 20.3 1.0
CA B:CYS111 4.5 12.6 1.0
CB B:SER113 4.7 10.2 1.0
NZ A:LYS103 4.7 15.8 1.0
N A:CYS132 4.8 20.3 1.0
O A:LEU104 5.0 11.5 1.0

Zinc binding site 2 out of 4 in 7ukh

Go back to Zinc Binding Sites List in 7ukh
Zinc binding site 2 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn901

b:27.1
occ:1.00
 ND1 B:HIS105 2.1 10.2 1.0
SG B:CYS133 2.3 17.3 1.0
SG B:CYS132 2.3 20.5 1.0
SG C:CYS111 2.3 12.6 1.0
CE1 B:HIS105 2.8 10.2 1.0
CB C:CYS111 3.1 12.6 1.0
CB B:CYS132 3.1 20.5 1.0
CG B:HIS105 3.2 10.2 1.0
CB B:CYS133 3.7 17.3 1.0
CB B:HIS105 3.8 10.2 1.0
N B:CYS133 3.8 17.3 1.0
C B:CYS132 4.0 20.5 1.0
NE2 B:HIS105 4.0 10.2 1.0
CA B:CYS132 4.1 20.5 1.0
CA B:HIS105 4.2 10.2 1.0
CD2 B:HIS105 4.2 10.2 1.0
CA B:CYS133 4.3 17.3 1.0
O B:CYS132 4.5 20.5 1.0
CA C:CYS111 4.5 12.6 1.0
CB C:SER113 4.6 10.2 1.0
NZ B:LYS103 4.7 16.1 1.0
N B:CYS132 4.8 20.5 1.0
O B:LEU104 5.0 11.3 1.0

Zinc binding site 3 out of 4 in 7ukh

Go back to Zinc Binding Sites List in 7ukh
Zinc binding site 3 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn901

b:27.5
occ:1.00
 ND1 C:HIS105 2.1 10.0 1.0
SG D:CYS111 2.3 12.9 1.0
SG C:CYS133 2.3 17.1 1.0
SG C:CYS132 2.3 20.2 1.0
CE1 C:HIS105 2.8 10.0 1.0
CB D:CYS111 3.1 12.9 1.0
CB C:CYS132 3.1 20.2 1.0
CG C:HIS105 3.2 10.0 1.0
CB C:CYS133 3.7 17.1 1.0
CB C:HIS105 3.8 10.0 1.0
N C:CYS133 3.8 17.1 1.0
C C:CYS132 4.0 20.2 1.0
NE2 C:HIS105 4.0 10.0 1.0
CA C:CYS132 4.1 20.2 1.0
CA C:HIS105 4.2 10.0 1.0
CD2 C:HIS105 4.2 10.0 1.0
CA C:CYS133 4.3 17.1 1.0
CA D:CYS111 4.5 12.9 1.0
O C:CYS132 4.5 20.2 1.0
CB D:SER113 4.6 10.3 1.0
NZ C:LYS103 4.7 15.8 1.0
N C:CYS132 4.8 20.2 1.0
O C:LEU104 5.0 11.2 1.0
N D:ALA114 5.0 8.2 1.0

Zinc binding site 4 out of 4 in 7ukh

Go back to Zinc Binding Sites List in 7ukh
Zinc binding site 4 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Intracellular Region within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn901

b:26.8
occ:1.00
 ND1 D:HIS105 2.1 10.3 1.0
SG A:CYS111 2.2 13.0 1.0
SG D:CYS133 2.3 17.5 1.0
SG D:CYS132 2.3 20.5 1.0
CE1 D:HIS105 2.8 10.3 1.0
CB A:CYS111 3.0 13.0 1.0
CB D:CYS132 3.1 20.5 1.0
CG D:HIS105 3.2 10.3 1.0
CB D:CYS133 3.7 17.5 1.0
CB D:HIS105 3.8 10.3 1.0
N D:CYS133 3.8 17.5 1.0
C D:CYS132 4.0 20.5 1.0
NE2 D:HIS105 4.0 10.3 1.0
CA D:CYS132 4.1 20.5 1.0
CA D:HIS105 4.2 10.3 1.0
CD2 D:HIS105 4.2 10.3 1.0
CA D:CYS133 4.3 17.5 1.0
CA A:CYS111 4.4 13.0 1.0
O D:CYS132 4.5 20.5 1.0
CB A:SER113 4.6 10.6 1.0
NZ D:LYS103 4.7 16.2 1.0
N D:CYS132 4.8 20.5 1.0
N A:ALA114 5.0 8.3 1.0
O D:LEU104 5.0 11.3 1.0

Reference:

W.Ye, H.Zhao, Y.Dai, Y.Wang, Y.H.Lo, L.Y.Jan, C.H.Lee. Activation and Closed-State Inactivation Mechanisms of the Human Voltage-Gated K V 4 Channel Complexes. Mol.Cell V. 82 2427 2022.
ISSN: ISSN 1097-2765
PubMed: 35597238
DOI: 10.1016/J.MOLCEL.2022.04.032
Page generated: Sat Apr 8 04:24:28 2023

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