Zinc in PDB 7uik: Mediator-Pic Early (Tail A + Upstream Dna & Activator)

The binding sites of Zinc atom in the Mediator-Pic Early (Tail A + Upstream Dna & Activator) (pdb code 7uik). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Mediator-Pic Early (Tail A + Upstream Dna & Activator), PDB code: 7uik:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Mediator-Pic Early (Tail A + Upstream Dna & Activator)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mediator-Pic Early (Tail A + Upstream Dna & Activator) within 5.0Å range: probe atom residue distance (Å) B Occ T:Zn201 b:77.5 occ:1.00 SG T:CYS21 1.9 48.5 1.0 SG T:CYS14 2.3 41.3 1.0 SG T:CYS11 2.5 53.0 1.0 SG T:CYS28 2.5 72.7 1.0 CB T:CYS11 2.9 50.6 1.0 ZN T:ZN202 3.2 77.6 1.0 CB T:CYS21 3.4 50.1 1.0 CB T:CYS14 3.5 49.7 1.0 CB T:CYS28 3.8 75.8 1.0 N T:CYS11 3.8 49.7 1.0 CA T:CYS11 3.9 51.0 1.0 CA T:CYS21 4.0 51.5 1.0 OH T:TYR40 4.2 72.1 1.0 N T:CYS14 4.5 50.9 1.0 N T:SER22 4.5 56.5 1.0 CA T:CYS14 4.6 49.9 1.0 C T:CYS21 4.7 53.9 1.0 N T:LYS23 4.7 65.5 1.0 C T:CYS11 4.8 50.9 1.0 O T:CYS11 4.8 50.4 1.0 SG T:CYS31 4.8 68.0 1.0 CZ T:TYR40 4.9 73.2 1.0

Zinc binding site 2 out of 4 in the Mediator-Pic Early (Tail A + Upstream Dna & Activator)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mediator-Pic Early (Tail A + Upstream Dna & Activator) within 5.0Å range: probe atom residue distance (Å) B Occ T:Zn202 b:77.6 occ:1.00 SG T:CYS31 2.3 68.0 1.0 SG T:CYS28 2.3 72.7 1.0 SG T:CYS38 2.3 76.2 1.0 SG T:CYS11 2.6 53.0 1.0 CB T:CYS31 3.0 71.3 1.0 CB T:CYS11 3.0 50.6 1.0 CB T:CYS38 3.2 78.1 1.0 ZN T:ZN201 3.2 77.5 1.0 CB T:CYS28 3.7 75.8 1.0 CA T:CYS38 3.8 78.3 1.0 N T:CYS28 4.1 76.7 1.0 CA T:CYS31 4.4 71.6 1.0 CA T:CYS28 4.4 76.0 1.0 C T:CYS38 4.4 77.7 1.0 OH T:TYR40 4.5 72.1 1.0 N T:CYS31 4.6 72.8 1.0 CA T:CYS11 4.6 51.0 1.0 N T:ARG39 4.8 77.1 1.0 O T:CYS28 4.8 76.3 1.0 SG T:CYS14 4.8 41.3 1.0 CZ T:TYR40 4.8 73.2 1.0 C T:CYS28 4.9 76.3 1.0 SG T:CYS21 4.9 48.5 1.0 CE1 T:TYR40 5.0 72.7 1.0 N T:CYS38 5.0 78.6 1.0

Zinc binding site 3 out of 4 in the Mediator-Pic Early (Tail A + Upstream Dna & Activator)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Mediator-Pic Early (Tail A + Upstream Dna & Activator) within 5.0Å range: probe atom residue distance (Å) B Occ U:Zn201 b:82.3 occ:1.00 SG U:CYS14 2.2 52.6 1.0 SG U:CYS21 2.2 65.0 1.0 SG U:CYS11 2.2 46.0 1.0 SG U:CYS28 2.7 72.9 1.0 CB U:CYS11 3.0 49.8 1.0 ZN U:ZN202 3.2 95.0 1.0 CB U:CYS21 3.3 63.8 1.0 CB U:CYS14 3.5 57.0 1.0 N U:CYS11 3.9 50.3 1.0 CB U:CYS28 3.9 77.9 1.0 CA U:CYS21 3.9 64.8 1.0 CA U:CYS11 4.0 50.6 1.0 SG U:CYS38 4.3 70.7 1.0 N U:CYS14 4.5 57.2 1.0 SG U:CYS31 4.6 74.6 1.0 CA U:CYS14 4.6 57.0 1.0 N U:SER22 4.6 65.7 1.0 C U:CYS11 4.7 52.5 1.0 O U:CYS11 4.7 52.3 1.0 OH U:TYR40 4.7 68.9 1.0 C U:CYS21 4.7 65.2 1.0 N U:LYS23 5.0 69.2 1.0

Zinc binding site 4 out of 4 in the Mediator-Pic Early (Tail A + Upstream Dna & Activator)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Mediator-Pic Early (Tail A + Upstream Dna & Activator) within 5.0Å range: probe atom residue distance (Å) B Occ U:Zn202 b:95.0 occ:1.00 SG U:CYS31 2.0 74.6 1.0 SG U:CYS38 2.0 70.7 1.0 SG U:CYS28 2.6 72.9 1.0 SG U:CYS11 2.6 46.0 1.0 CB U:CYS31 2.8 78.3 1.0 CB U:CYS38 3.0 73.6 1.0 ZN U:ZN201 3.2 82.3 1.0 CB U:CYS11 3.2 49.8 1.0 CA U:CYS38 3.6 73.8 1.0 CA U:CYS31 4.1 78.0 1.0 N U:CYS31 4.2 79.6 1.0 CB U:CYS28 4.3 77.9 1.0 SG U:CYS14 4.5 52.6 1.0 C U:CYS38 4.5 74.2 1.0 CA U:CYS11 4.7 50.6 1.0 N U:CYS38 4.7 74.7 1.0 N U:ARG39 4.7 74.2 1.0 N U:CYS28 4.7 79.5 1.0 O U:CYS28 4.8 78.3 1.0 CB U:ILE13 4.9 58.6 1.0 CA U:CYS28 5.0 78.4 1.0

J.J.Gorbea Colon, L.Palao 3Rd, S.F.Chen, H.J.Kim, L.Snyder, Y.W.Chang, K.L.Tsai, K.Murakami. Structural Basis of A Transcription Pre-Initiation Complex on A Divergent Promoter. Mol.Cell 2023.
ISSN: ISSN 1097-2765
PubMed: 36731470
DOI: 10.1016/J.MOLCEL.2023.01.011