Zinc in PDB 7txu: Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg)

All present enzymatic activity of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg):
6.3.2.29; 6.3.2.30;

The structure of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg) also contains other interesting chemical elements:

Magnesium

(Mg)

16 atoms

The binding sites of Zinc atom in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg) (pdb code 7txu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg), PDB code: 7txu:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn904 b:103.4 occ:1.00 NE2 A:HIS79 2.1 51.9 1.0 NE2 A:HIS83 2.2 51.4 1.0 SG A:CYS59 2.3 66.2 1.0 CE1 A:HIS79 2.7 51.9 1.0 CB A:CYS59 3.0 66.2 1.0 CE1 A:HIS83 3.1 51.4 1.0 O I:7ID4 3.2 47.6 1.0 CD2 A:HIS79 3.3 51.9 1.0 CD2 A:HIS83 3.3 51.4 1.0 CA A:CYS59 3.4 66.2 1.0 ND1 A:HIS79 3.9 51.9 1.0 C I:7ID4 4.0 47.6 1.0 CG A:HIS79 4.2 51.9 1.0 C A:CYS59 4.2 66.2 1.0 ND1 A:HIS83 4.2 51.4 1.0 CG A:HIS83 4.4 51.4 1.0 N A:SER60 4.4 67.6 1.0 N A:CYS59 4.5 66.2 1.0 OE1 A:GLU82 4.5 46.6 1.0 CD1 A:PHE67 4.7 65.3 1.0 MG I:MG101 4.8 45.8 1.0 OE2 A:GLU82 4.8 46.6 1.0 O A:HIS79 4.9 51.9 1.0 CB I:7ID4 4.9 47.6 1.0

Zinc binding site 2 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn904 b:101.3 occ:1.00 NE2 B:HIS79 2.1 52.6 1.0 NE2 B:HIS83 2.2 52.0 1.0 SG B:CYS59 2.3 65.2 1.0 CE1 B:HIS79 2.7 52.6 1.0 CB B:CYS59 3.0 65.2 1.0 CE1 B:HIS83 3.1 52.0 1.0 CD2 B:HIS79 3.3 52.6 1.0 CD2 B:HIS83 3.3 52.0 1.0 CA B:CYS59 3.4 65.2 1.0 ND1 B:HIS79 3.9 52.6 1.0 C J:7ID4 4.0 48.1 1.0 CG B:HIS79 4.2 52.6 1.0 C B:CYS59 4.2 65.2 1.0 ND1 B:HIS83 4.2 52.0 1.0 O J:7ID4 4.4 48.1 1.0 CG B:HIS83 4.4 52.0 1.0 N B:SER60 4.4 65.7 1.0 N B:CYS59 4.5 65.2 1.0 OE1 B:GLU82 4.5 46.6 1.0 CD1 B:PHE67 4.7 64.2 1.0 MG B:MG907 4.8 43.1 1.0 OE2 B:GLU82 4.8 46.6 1.0 O B:HIS79 4.9 52.6 1.0 CB J:7ID4 4.9 48.1 1.0

Zinc binding site 3 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn904 b:100.6 occ:1.00 NE2 C:HIS79 2.1 52.9 1.0 NE2 C:HIS83 2.2 52.0 1.0 SG C:CYS59 2.3 64.8 1.0 CE1 C:HIS79 2.7 52.9 1.0 CB C:CYS59 3.0 64.8 1.0 CE1 C:HIS83 3.1 52.0 1.0 CD2 C:HIS79 3.3 52.9 1.0 CD2 C:HIS83 3.3 52.0 1.0 CA C:CYS59 3.4 64.8 1.0 ND1 C:HIS79 3.9 52.9 1.0 C K:7ID4 4.0 48.8 1.0 CG C:HIS79 4.2 52.9 1.0 C C:CYS59 4.2 64.8 1.0 ND1 C:HIS83 4.2 52.0 1.0 O K:7ID4 4.4 48.8 1.0 CG C:HIS83 4.4 52.0 1.0 N C:SER60 4.4 65.1 1.0 N C:CYS59 4.5 64.8 1.0 OE1 C:GLU82 4.5 47.4 1.0 CD1 C:PHE67 4.7 63.2 1.0 MG C:MG907 4.8 44.2 1.0 OE2 C:GLU82 4.8 47.4 1.0 O C:HIS79 4.9 52.9 1.0 CB K:7ID4 4.9 48.8 1.0

Zinc binding site 4 out of 4 in the Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Cyanophycin Synthetase 1 From Synechocystis Sp. UTEX2470 with Atp and 16X(Asp-Arg) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn904 b:102.8 occ:1.00 NE2 D:HIS79 2.1 52.7 1.0 NE2 D:HIS83 2.2 52.3 1.0 SG D:CYS59 2.3 66.0 1.0 CE1 D:HIS79 2.7 52.7 1.0 CB D:CYS59 3.0 66.0 1.0 CE1 D:HIS83 3.1 52.3 1.0 O L:7ID4 3.2 49.0 1.0 CD2 D:HIS79 3.3 52.7 1.0 CD2 D:HIS83 3.3 52.3 1.0 CA D:CYS59 3.4 66.0 1.0 ND1 D:HIS79 3.9 52.7 1.0 C L:7ID4 4.0 49.0 1.0 CG D:HIS79 4.2 52.7 1.0 C D:CYS59 4.2 66.0 1.0 ND1 D:HIS83 4.2 52.3 1.0 CG D:HIS83 4.4 52.3 1.0 N D:SER60 4.4 65.6 1.0 N D:CYS59 4.5 66.0 1.0 OE1 D:GLU82 4.5 47.5 1.0 CD1 D:PHE67 4.7 64.8 1.0 MG L:MG101 4.8 46.0 1.0 OE2 D:GLU82 4.8 47.5 1.0 O D:HIS79 4.9 52.7 1.0 CB L:7ID4 4.9 49.0 1.0

I.Sharon, S.Pinus, M.Grogg, N.Moitessier, D.Hilvert, T.M.Schmeing. A Cryptic Third Active Site in Cyanophycin Synthetase Creates Primers For Polymerization Nat Commun V. 13 3923 2022.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-022-31542-7