Zinc in PDB 7s7c: Human Nuclear Exosome Targeting (Next) Complex Bound to Rna (Substrate 2)

All present enzymatic activity of Human Nuclear Exosome Targeting (Next) Complex Bound to Rna (Substrate 2):
3.6.4.13;

The binding sites of Zinc atom in the Human Nuclear Exosome Targeting (Next) Complex Bound to Rna (Substrate 2) (pdb code 7s7c). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Human Nuclear Exosome Targeting (Next) Complex Bound to Rna (Substrate 2), PDB code: 7s7c:

Zinc binding site 1 out of 1 in the Human Nuclear Exosome Targeting (Next) Complex Bound to Rna (Substrate 2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Nuclear Exosome Targeting (Next) Complex Bound to Rna (Substrate 2) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn900 b:182.1 occ:1.00 NE2 B:HIS237 2.0 147.6 1.0 OG B:SER234 2.1 150.1 1.0 SG B:CYS242 2.3 145.3 1.0 SG B:CYS232 2.3 149.3 1.0 SG B:CYS229 2.3 150.2 1.0 CD2 B:HIS237 2.7 147.6 1.0 CB B:CYS242 3.0 145.3 1.0 CE1 B:HIS237 3.2 147.6 1.0 CB B:CYS229 3.4 150.2 1.0 CB B:CYS232 3.4 149.3 1.0 CB B:SER234 3.4 150.1 1.0 N B:CYS232 3.7 149.3 1.0 CG B:HIS237 4.0 147.6 1.0 CA B:CYS232 4.1 149.3 1.0 N B:SER234 4.2 150.1 1.0 ND1 B:HIS237 4.2 147.6 1.0 CA B:CYS242 4.3 145.3 1.0 CA B:SER234 4.4 150.1 1.0 CB B:ASN231 4.6 148.1 1.0 C B:CYS232 4.6 149.3 1.0 O B:CYS229 4.7 150.2 1.0 CA B:CYS229 4.7 150.2 1.0 C B:ASN231 4.7 148.1 1.0 N B:GLY233 4.8 150.4 1.0 CE B:MET244 4.8 143.4 1.0 O B:SER234 4.9 150.1 1.0 O B:MET244 4.9 143.4 1.0 O B:GLN238 4.9 146.0 1.0 C B:CYS229 4.9 150.2 1.0

M.R.Puno, C.D.Lima. Structural Basis For Rna Surveillance By the Human Nuclear Exosome Targeting (Next) Complex. Cell V. 185 2132 2022.
ISSN: ISSN 1097-4172
PubMed: 35688134
DOI: 10.1016/J.CELL.2022.04.016