Zinc in PDB 7m4m: Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Enzymatic activity of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
All present enzymatic activity of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin:
2.3.2.27;
Protein crystallography data
The structure of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin, PDB code: 7m4m
was solved by
T.R.Cotton,
B.C.Lechtenberg,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
47.46 /
2.39
|
Space group
|
P 41 21 2
|
Cell size a, b, c (Å), α, β, γ (°)
|
81.871,
81.871,
248.656,
90,
90,
90
|
R / Rfree (%)
|
20 /
24.7
|
Zinc Binding Sites:
The binding sites of Zinc atom in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
(pdb code 7m4m). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 10 binding sites of Zinc where determined in the
Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin, PDB code: 7m4m:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 1 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn801
b:37.0
occ:1.00
|
SG
|
A:CYS623
|
2.2
|
43.7
|
1.0
|
SG
|
A:CYS605
|
2.2
|
45.6
|
1.0
|
SG
|
A:CYS628
|
2.3
|
43.4
|
1.0
|
SG
|
A:CYS608
|
2.3
|
45.8
|
1.0
|
CB
|
A:CYS605
|
3.0
|
30.0
|
1.0
|
CB
|
A:CYS628
|
3.0
|
45.5
|
1.0
|
CB
|
A:CYS623
|
3.1
|
33.9
|
1.0
|
CB
|
A:CYS608
|
3.7
|
44.0
|
1.0
|
N
|
A:CYS608
|
3.9
|
54.2
|
1.0
|
CA
|
A:CYS608
|
4.3
|
32.7
|
1.0
|
CA
|
A:CYS628
|
4.4
|
38.5
|
1.0
|
CA
|
A:CYS605
|
4.5
|
37.5
|
1.0
|
CA
|
A:CYS623
|
4.5
|
30.1
|
1.0
|
CB
|
A:ASN625
|
4.5
|
44.6
|
1.0
|
CB
|
A:PHE610
|
4.7
|
29.2
|
1.0
|
CB
|
A:SER607
|
4.7
|
35.7
|
1.0
|
N
|
A:ARG629
|
4.7
|
53.7
|
1.0
|
C
|
A:CYS628
|
4.8
|
43.8
|
1.0
|
C
|
A:CYS608
|
4.9
|
42.7
|
1.0
|
N
|
A:PHE610
|
4.9
|
42.6
|
1.0
|
N
|
A:SER609
|
4.9
|
40.5
|
1.0
|
N
|
A:LYS630
|
4.9
|
41.9
|
1.0
|
C
|
A:SER607
|
5.0
|
40.9
|
1.0
|
|
Zinc binding site 2 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 2 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn802
b:59.0
occ:1.00
|
NE2
|
A:HIS643
|
2.1
|
50.9
|
1.0
|
SG
|
A:CYS636
|
2.3
|
45.6
|
1.0
|
SG
|
A:CYS648
|
2.3
|
56.5
|
1.0
|
SG
|
A:CYS633
|
2.4
|
58.0
|
1.0
|
CD2
|
A:HIS643
|
2.9
|
49.6
|
1.0
|
CB
|
A:CYS633
|
3.2
|
45.2
|
1.0
|
CE1
|
A:HIS643
|
3.2
|
50.5
|
1.0
|
CB
|
A:CYS648
|
3.5
|
61.5
|
1.0
|
CB
|
A:CYS636
|
3.6
|
55.2
|
1.0
|
CA
|
A:CYS648
|
3.8
|
62.8
|
1.0
|
N
|
A:CYS636
|
4.0
|
61.7
|
1.0
|
CG
|
A:HIS643
|
4.1
|
50.7
|
1.0
|
ND1
|
A:HIS643
|
4.2
|
51.7
|
1.0
|
N
|
A:CYS648
|
4.3
|
54.9
|
1.0
|
CA
|
A:CYS636
|
4.4
|
46.6
|
1.0
|
CA
|
A:CYS633
|
4.7
|
41.4
|
1.0
|
CB
|
A:LYS635
|
4.8
|
56.2
|
1.0
|
N
|
A:GLY638
|
5.0
|
33.4
|
1.0
|
C
|
A:CYS636
|
5.0
|
41.6
|
1.0
|
N
|
A:LYS635
|
5.0
|
50.4
|
1.0
|
|
Zinc binding site 3 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 3 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn803
b:49.7
occ:1.00
|
SG
|
A:CYS678
|
2.3
|
56.8
|
1.0
|
SG
|
A:CYS695
|
2.3
|
50.2
|
1.0
|
SG
|
A:CYS675
|
2.3
|
33.4
|
1.0
|
SG
|
A:CYS693
|
2.3
|
46.1
|
1.0
|
CB
|
A:CYS675
|
3.1
|
35.8
|
1.0
|
CB
|
A:CYS695
|
3.2
|
33.9
|
1.0
|
CB
|
A:CYS678
|
3.3
|
40.3
|
1.0
|
CB
|
A:CYS693
|
3.3
|
43.1
|
1.0
|
N
|
A:CYS678
|
3.7
|
45.2
|
1.0
|
N
|
A:CYS695
|
4.1
|
47.5
|
1.0
|
CA
|
A:CYS678
|
4.1
|
40.2
|
1.0
|
CA
|
A:CYS695
|
4.3
|
41.0
|
1.0
|
CA
|
A:CYS675
|
4.5
|
32.8
|
1.0
|
CB
|
A:LYS677
|
4.7
|
38.7
|
1.0
|
CA
|
A:CYS693
|
4.7
|
33.9
|
1.0
|
C
|
A:CYS678
|
4.7
|
39.1
|
1.0
|
N
|
A:GLY679
|
4.8
|
41.6
|
1.0
|
OG1
|
A:THR680
|
4.8
|
45.0
|
1.0
|
C
|
A:LYS677
|
4.8
|
43.7
|
1.0
|
CB
|
A:THR680
|
4.9
|
39.0
|
1.0
|
N
|
A:ARG694
|
4.9
|
44.0
|
1.0
|
CB
|
A:ALA697
|
4.9
|
33.3
|
1.0
|
C
|
A:CYS693
|
5.0
|
48.0
|
1.0
|
N
|
A:THR680
|
5.0
|
33.8
|
1.0
|
|
Zinc binding site 4 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 4 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn804
b:51.9
occ:1.00
|
SG
|
A:CYS700
|
2.1
|
57.6
|
1.0
|
NE2
|
A:HIS712
|
2.1
|
33.0
|
1.0
|
SG
|
A:CYS703
|
2.3
|
43.2
|
1.0
|
SG
|
A:CYS730
|
2.3
|
55.7
|
1.0
|
CB
|
A:CYS700
|
2.9
|
51.4
|
1.0
|
CD2
|
A:HIS712
|
2.9
|
43.4
|
1.0
|
CB
|
A:CYS730
|
3.1
|
47.8
|
1.0
|
CE1
|
A:HIS712
|
3.2
|
43.2
|
1.0
|
CB
|
A:CYS703
|
3.7
|
55.8
|
1.0
|
N
|
A:CYS703
|
4.0
|
56.5
|
1.0
|
CG
|
A:HIS712
|
4.1
|
40.3
|
1.0
|
ND1
|
A:HIS712
|
4.2
|
54.9
|
1.0
|
CA
|
A:CYS700
|
4.3
|
40.8
|
1.0
|
CA
|
A:CYS703
|
4.4
|
48.3
|
1.0
|
CE1
|
A:PHE713
|
4.5
|
36.4
|
1.0
|
CA
|
A:CYS730
|
4.5
|
43.7
|
1.0
|
CB
|
A:LEU702
|
4.6
|
44.9
|
1.0
|
N
|
A:CYS730
|
4.8
|
54.0
|
1.0
|
C
|
A:CYS700
|
4.8
|
47.4
|
1.0
|
CD1
|
A:PHE713
|
4.9
|
28.8
|
1.0
|
O
|
A:CYS700
|
5.0
|
48.5
|
1.0
|
|
Zinc binding site 5 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 5 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn805
b:59.0
occ:1.00
|
ND1
|
A:HIS716
|
2.0
|
33.9
|
1.0
|
SG
|
A:CYS714
|
2.3
|
57.5
|
1.0
|
SG
|
A:CYS724
|
2.3
|
43.1
|
1.0
|
SG
|
A:CYS727
|
2.3
|
55.7
|
1.0
|
CE1
|
A:HIS716
|
3.0
|
60.6
|
1.0
|
CG
|
A:HIS716
|
3.1
|
50.3
|
1.0
|
CB
|
A:CYS714
|
3.3
|
54.4
|
1.0
|
CB
|
A:HIS716
|
3.4
|
55.4
|
1.0
|
CB
|
A:CYS727
|
3.6
|
56.2
|
1.0
|
CB
|
A:CYS724
|
3.6
|
57.9
|
1.0
|
CA
|
A:CYS714
|
4.0
|
42.3
|
1.0
|
N
|
A:HIS716
|
4.0
|
48.8
|
1.0
|
NE2
|
A:HIS716
|
4.1
|
65.0
|
1.0
|
N
|
A:CYS727
|
4.2
|
50.7
|
1.0
|
CD2
|
A:HIS716
|
4.2
|
54.8
|
1.0
|
CA
|
A:HIS716
|
4.4
|
47.0
|
1.0
|
CA
|
A:CYS727
|
4.4
|
44.5
|
1.0
|
C
|
A:CYS714
|
4.4
|
34.5
|
1.0
|
N
|
A:GLN715
|
4.5
|
42.9
|
1.0
|
C
|
A:GLU726
|
4.8
|
49.3
|
1.0
|
NH1
|
A:ARG718
|
4.8
|
48.2
|
1.0
|
NH2
|
A:ARG729
|
4.9
|
66.3
|
1.0
|
C
|
A:CYS727
|
4.9
|
55.4
|
1.0
|
CA
|
A:CYS724
|
4.9
|
54.7
|
1.0
|
CB
|
A:GLU726
|
4.9
|
41.6
|
1.0
|
|
Zinc binding site 6 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 6 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn801
b:48.1
occ:1.00
|
SG
|
B:CYS623
|
2.2
|
57.8
|
1.0
|
SG
|
B:CYS628
|
2.2
|
48.2
|
1.0
|
SG
|
B:CYS605
|
2.3
|
37.5
|
1.0
|
SG
|
B:CYS608
|
2.3
|
58.3
|
1.0
|
CB
|
B:CYS628
|
2.8
|
54.0
|
1.0
|
CB
|
B:CYS605
|
3.0
|
32.8
|
1.0
|
CB
|
B:CYS623
|
3.1
|
38.7
|
1.0
|
CB
|
B:CYS608
|
3.7
|
42.9
|
1.0
|
N
|
B:CYS608
|
3.9
|
46.3
|
1.0
|
CB
|
B:ASN625
|
4.2
|
50.1
|
1.0
|
CA
|
B:CYS628
|
4.3
|
56.1
|
1.0
|
CA
|
B:CYS608
|
4.3
|
43.3
|
1.0
|
CB
|
B:PHE610
|
4.4
|
43.6
|
1.0
|
CA
|
B:CYS605
|
4.5
|
28.5
|
1.0
|
CA
|
B:CYS623
|
4.5
|
41.2
|
1.0
|
N
|
B:ARG629
|
4.6
|
60.6
|
1.0
|
N
|
B:PHE610
|
4.7
|
47.7
|
1.0
|
ND2
|
B:ASN625
|
4.7
|
52.0
|
1.0
|
C
|
B:CYS628
|
4.7
|
51.9
|
1.0
|
CB
|
B:SER607
|
4.8
|
51.9
|
1.0
|
C
|
B:CYS608
|
4.8
|
51.9
|
1.0
|
N
|
B:SER609
|
4.8
|
49.4
|
1.0
|
|
Zinc binding site 7 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 7 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn802
b:59.3
occ:1.00
|
NE2
|
B:HIS643
|
2.1
|
58.2
|
1.0
|
SG
|
B:CYS648
|
2.3
|
55.1
|
1.0
|
SG
|
B:CYS636
|
2.3
|
70.9
|
1.0
|
SG
|
B:CYS633
|
2.4
|
53.7
|
1.0
|
CD2
|
B:HIS643
|
3.0
|
55.4
|
1.0
|
CE1
|
B:HIS643
|
3.2
|
62.0
|
1.0
|
CB
|
B:CYS633
|
3.3
|
36.2
|
1.0
|
CB
|
B:CYS648
|
3.5
|
55.0
|
1.0
|
CB
|
B:CYS636
|
3.7
|
55.5
|
1.0
|
CA
|
B:CYS648
|
3.8
|
65.8
|
1.0
|
N
|
B:CYS636
|
4.1
|
53.5
|
1.0
|
N
|
B:CYS648
|
4.2
|
64.1
|
1.0
|
CG
|
B:HIS643
|
4.2
|
62.5
|
1.0
|
ND1
|
B:HIS643
|
4.3
|
71.6
|
1.0
|
CA
|
B:CYS636
|
4.4
|
46.5
|
1.0
|
CB
|
B:LYS635
|
4.7
|
37.8
|
1.0
|
NZ
|
B:LYS635
|
4.8
|
76.0
|
1.0
|
CA
|
B:CYS633
|
4.8
|
41.0
|
1.0
|
C
|
B:THR647
|
4.9
|
66.6
|
1.0
|
CE
|
B:LYS635
|
5.0
|
82.5
|
1.0
|
|
Zinc binding site 8 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 8 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn803
b:57.5
occ:1.00
|
SG
|
B:CYS678
|
2.3
|
61.2
|
1.0
|
SG
|
B:CYS695
|
2.3
|
58.6
|
1.0
|
SG
|
B:CYS675
|
2.3
|
56.2
|
1.0
|
SG
|
B:CYS693
|
2.3
|
64.1
|
1.0
|
CB
|
B:CYS675
|
3.0
|
47.5
|
1.0
|
CB
|
B:CYS693
|
3.1
|
60.9
|
1.0
|
CB
|
B:CYS695
|
3.3
|
67.5
|
1.0
|
CB
|
B:CYS678
|
3.4
|
52.6
|
1.0
|
N
|
B:CYS678
|
3.8
|
50.3
|
1.0
|
N
|
B:CYS695
|
4.1
|
59.7
|
1.0
|
CA
|
B:CYS678
|
4.1
|
36.0
|
1.0
|
CA
|
B:CYS695
|
4.3
|
60.9
|
1.0
|
CA
|
B:CYS675
|
4.5
|
46.1
|
1.0
|
CA
|
B:CYS693
|
4.5
|
41.8
|
1.0
|
C
|
B:CYS678
|
4.7
|
47.8
|
1.0
|
CB
|
B:ALA697
|
4.8
|
60.4
|
1.0
|
CB
|
B:LYS677
|
4.8
|
56.0
|
1.0
|
N
|
B:GLY679
|
4.8
|
46.4
|
1.0
|
C
|
B:CYS693
|
4.8
|
50.2
|
1.0
|
N
|
B:ARG694
|
4.8
|
50.2
|
1.0
|
OG1
|
B:THR680
|
4.9
|
73.5
|
1.0
|
C
|
B:LYS677
|
4.9
|
42.3
|
1.0
|
CB
|
B:THR680
|
4.9
|
54.3
|
1.0
|
N
|
B:THR680
|
5.0
|
57.3
|
1.0
|
C
|
B:CYS675
|
5.0
|
54.8
|
1.0
|
|
Zinc binding site 9 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 9 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn804
b:52.6
occ:1.00
|
SG
|
B:CYS700
|
2.1
|
48.4
|
1.0
|
NE2
|
B:HIS712
|
2.1
|
47.0
|
1.0
|
SG
|
B:CYS703
|
2.2
|
47.6
|
1.0
|
SG
|
B:CYS730
|
2.3
|
55.1
|
1.0
|
CD2
|
B:HIS712
|
2.9
|
54.3
|
1.0
|
CB
|
B:CYS700
|
3.1
|
35.3
|
1.0
|
CB
|
B:CYS730
|
3.1
|
48.6
|
1.0
|
CE1
|
B:HIS712
|
3.2
|
56.1
|
1.0
|
CB
|
B:CYS703
|
3.6
|
46.6
|
1.0
|
N
|
B:CYS703
|
3.9
|
49.8
|
1.0
|
CG
|
B:HIS712
|
4.1
|
43.8
|
1.0
|
ND1
|
B:HIS712
|
4.2
|
58.8
|
1.0
|
CA
|
B:CYS703
|
4.3
|
42.3
|
1.0
|
CA
|
B:CYS700
|
4.5
|
40.4
|
1.0
|
CA
|
B:CYS730
|
4.5
|
43.5
|
1.0
|
CB
|
B:LEU702
|
4.6
|
48.2
|
1.0
|
CE1
|
B:PHE713
|
4.7
|
43.1
|
1.0
|
N
|
B:CYS730
|
4.8
|
44.6
|
1.0
|
C
|
B:CYS700
|
4.9
|
43.0
|
1.0
|
C
|
B:LEU702
|
4.9
|
36.2
|
1.0
|
|
Zinc binding site 10 out
of 10 in 7m4m
Go back to
Zinc Binding Sites List in 7m4m
Zinc binding site 10 out
of 10 in the Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Crystal Structure of Rbr E3 Ligase RNF216 with Ubiquitin within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn805
b:51.6
occ:1.00
|
ND1
|
B:HIS716
|
2.0
|
37.5
|
1.0
|
SG
|
B:CYS724
|
2.2
|
46.1
|
1.0
|
SG
|
B:CYS727
|
2.2
|
46.3
|
1.0
|
SG
|
B:CYS714
|
2.3
|
39.5
|
1.0
|
CE1
|
B:HIS716
|
3.0
|
49.5
|
1.0
|
CG
|
B:HIS716
|
3.0
|
46.4
|
1.0
|
CB
|
B:CYS714
|
3.3
|
48.5
|
1.0
|
CB
|
B:HIS716
|
3.4
|
53.5
|
1.0
|
CB
|
B:CYS727
|
3.5
|
53.5
|
1.0
|
CB
|
B:CYS724
|
3.6
|
54.8
|
1.0
|
N
|
B:CYS727
|
4.0
|
41.1
|
1.0
|
N
|
B:HIS716
|
4.1
|
46.0
|
1.0
|
NE2
|
B:HIS716
|
4.1
|
52.9
|
1.0
|
CA
|
B:CYS714
|
4.1
|
46.6
|
1.0
|
CD2
|
B:HIS716
|
4.2
|
47.8
|
1.0
|
CA
|
B:CYS727
|
4.2
|
47.5
|
1.0
|
CA
|
B:HIS716
|
4.4
|
38.1
|
1.0
|
C
|
B:CYS714
|
4.5
|
44.0
|
1.0
|
C
|
B:GLU726
|
4.6
|
47.9
|
1.0
|
N
|
B:GLN715
|
4.6
|
50.3
|
1.0
|
C
|
B:CYS727
|
4.8
|
59.1
|
1.0
|
CB
|
B:GLU726
|
4.8
|
47.6
|
1.0
|
CA
|
B:CYS724
|
4.9
|
41.6
|
1.0
|
NH2
|
B:ARG729
|
5.0
|
59.4
|
1.0
|
|
Reference:
T.R.Cotton,
S.A.Cobbold,
J.P.Bernardini,
L.W.Richardson,
X.S.Wang,
B.C.Lechtenberg.
Structural Basis of K63-Ubiquitin Chain Formation By the Gordon-Holmes Syndrome Rbr E3 Ubiquitin Ligase RNF216 Mol.Cell 2022.
ISSN: ISSN 1097-2765
Page generated: Tue Oct 29 23:08:31 2024
|