Atomistry » Zinc » PDB 7b8e-7bos » 7bfz
Atomistry »
  Zinc »
    PDB 7b8e-7bos »
      7bfz »

Zinc in PDB 7bfz: X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490

Enzymatic activity of X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490

All present enzymatic activity of X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490:
3.4.17.21;

Protein crystallography data

The structure of X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490, PDB code: 7bfz was solved by A.Rakhimbekova, L.Motlova, C.Barinka, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.96 / 1.73
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 101.54, 130.103, 158.91, 90, 90, 90
R / Rfree (%) 16.3 / 18.3

Other elements in 7bfz:

The structure of X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490 also contains other interesting chemical elements:

Sodium (Na) 2 atoms
Chlorine (Cl) 1 atom
Calcium (Ca) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490 (pdb code 7bfz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490, PDB code: 7bfz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 7bfz

Go back to Zinc Binding Sites List in 7bfz
Zinc binding site 1 out of 2 in the X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn801

b:25.7
occ:1.00
O A:HOH1202 2.0 24.0 1.0
OD2 A:ASP387 2.0 26.6 1.0
NE2 A:HIS553 2.0 24.6 1.0
OE2 A:GLU425 2.1 24.1 1.0
OE1 A:GLU425 2.4 24.9 1.0
O6 A:TKZ813 2.5 25.5 1.0
CD A:GLU425 2.6 25.1 1.0
CE1 A:HIS553 2.9 24.3 1.0
CG A:ASP387 3.0 26.6 1.0
CD2 A:HIS553 3.1 25.0 1.0
ZN A:ZN802 3.3 25.2 1.0
C2 A:TKZ813 3.3 27.3 1.0
OD1 A:ASP387 3.4 23.9 1.0
N2 A:TKZ813 3.8 24.9 1.0
CE1 A:TYR552 4.0 24.7 1.0
C5 A:TKZ813 4.0 23.9 1.0
ND1 A:HIS553 4.1 23.5 1.0
OE1 A:GLU424 4.1 23.8 1.0
CG A:GLU425 4.2 23.6 1.0
O A:HOH951 4.2 25.1 1.0
CG A:HIS553 4.2 24.3 1.0
N1 A:TKZ813 4.3 24.6 1.0
CB A:ASP387 4.3 25.3 1.0
OH A:TYR552 4.3 24.8 1.0
NE2 A:HIS377 4.5 23.6 1.0
CZ A:TYR552 4.5 26.2 1.0
C6 A:TKZ813 4.6 24.8 1.0
CD1 A:TRP381 4.6 25.6 1.0
C3 A:TKZ813 4.7 26.5 1.0
CE1 A:HIS377 4.7 24.3 1.0
NE1 A:TRP381 4.8 24.8 1.0
O5 A:TKZ813 4.8 24.5 1.0
OD2 A:ASP453 4.9 25.2 1.0
CD1 A:TYR552 4.9 26.5 1.0
CD A:GLU424 5.0 23.9 1.0

Zinc binding site 2 out of 2 in 7bfz

Go back to Zinc Binding Sites List in 7bfz
Zinc binding site 2 out of 2 in the X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn802

b:25.2
occ:1.00
O A:HOH1202 1.8 24.0 1.0
OD2 A:ASP453 2.0 25.2 1.0
NE2 A:HIS377 2.0 23.6 1.0
OD1 A:ASP387 2.0 23.9 1.0
CG A:ASP453 2.7 26.3 1.0
OD1 A:ASP453 2.8 27.2 1.0
CG A:ASP387 2.9 26.6 1.0
CE1 A:HIS377 3.0 24.3 1.0
CD2 A:HIS377 3.0 22.9 1.0
OD2 A:ASP387 3.2 26.6 1.0
ZN A:ZN801 3.3 25.7 1.0
OE2 A:GLU425 3.6 24.1 1.0
OE1 A:GLU424 3.7 23.8 1.0
CD A:GLU424 4.0 23.9 1.0
ND1 A:HIS377 4.1 24.7 1.0
OE2 A:GLU424 4.1 23.5 1.0
CG A:HIS377 4.2 23.6 1.0
CB A:ASP453 4.2 23.6 1.0
CB A:ASP387 4.2 25.3 1.0
ND2 A:ASN519 4.2 22.4 1.0
CB A:PRO388 4.3 24.3 1.0
CD A:GLU425 4.3 25.1 1.0
C2 A:TKZ813 4.4 27.3 1.0
O6 A:TKZ813 4.4 25.5 1.0
CA A:PRO388 4.6 25.2 1.0
CA A:ASP387 4.6 26.8 1.0
C A:ASP387 4.6 25.4 1.0
OE1 A:GLU425 4.6 24.9 1.0
N1 A:TKZ813 4.6 24.6 1.0
N A:PRO388 4.7 25.6 1.0
OG A:SER454 4.7 20.6 0.7
O A:HOH1068 4.8 31.8 1.0
N2 A:TKZ813 4.8 24.9 1.0
CG A:GLU424 4.9 22.4 1.0

Reference:

A.Rakhimbekova, L.Motlova, C.Barinka. X-Ray Structure of Human Prostate-Specific Membrane Antigen(Psma) in Complex with A Inhibitor Glu-490 To Be Published.
Page generated: Tue Oct 29 17:35:10 2024

Last articles

Zn in 9FD2
Zn in 9GUW
Zn in 9GUX
Zn in 9F7C
Zn in 9GUR
Zn in 9F7A
Zn in 9DDE
Zn in 9DBY
Zn in 9EBZ
Zn in 9DGG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy