Zinc in PDB 7bah: Structure of Rig-I Ctd Bound to Oh-Rna

All present enzymatic activity of Structure of Rig-I Ctd Bound to Oh-Rna:
3.6.4.13;

The structure of Structure of Rig-I Ctd Bound to Oh-Rna, PDB code: 7bah was solved by K.Anand, G.Hagelueken, D.Fusshoeller, M.Geyer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.92 / 1.89
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	81.92, 81.92, 111.87, 90, 90, 120
R / Rfree (%)	19.5 / 22.4

The binding sites of Zinc atom in the Structure of Rig-I Ctd Bound to Oh-Rna (pdb code 7bah). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Rig-I Ctd Bound to Oh-Rna, PDB code: 7bah:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Rig-I Ctd Bound to Oh-Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Rig-I Ctd Bound to Oh-Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1001 b:33.9 occ:1.00 SG A:CYS869 2.3 35.1 1.0 SG A:CYS813 2.3 32.7 1.0 SG A:CYS864 2.3 30.0 1.0 SG A:CYS810 2.3 29.7 1.0 CB A:CYS864 3.1 25.7 1.0 CB A:CYS869 3.2 32.6 1.0 CB A:CYS810 3.2 24.0 1.0 CB A:CYS813 3.4 30.6 1.0 N A:CYS813 3.9 28.1 1.0 CA A:CYS813 4.2 29.5 1.0 CB A:HIS871 4.4 27.9 1.0 CZ2 A:TRP873 4.5 28.1 1.0 CA A:CYS864 4.6 25.7 1.0 CA A:CYS869 4.6 35.3 1.0 CB A:ARG866 4.6 38.0 1.0 CA A:CYS810 4.6 26.7 1.0 CG A:ARG866 4.6 39.8 1.0 NE1 A:TRP873 4.7 24.3 1.0 N A:HIS871 4.7 29.1 1.0 CB A:LYS812 4.8 29.1 1.0 N A:SER870 4.8 31.4 1.0 O A:HOH1166 4.8 31.3 1.0 C A:CYS813 4.9 31.6 1.0 CB A:ALA815 4.9 33.1 1.0 CE2 A:TRP873 4.9 27.8 1.0 C A:LYS812 5.0 29.2 1.0 C A:CYS869 5.0 30.3 1.0

Zinc binding site 2 out of 2 in the Structure of Rig-I Ctd Bound to Oh-Rna


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Rig-I Ctd Bound to Oh-Rna within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1001 b:35.3 occ:1.00 SG B:CYS813 2.3 35.9 1.0 SG B:CYS869 2.3 32.4 1.0 SG B:CYS864 2.3 32.7 1.0 SG B:CYS810 2.3 29.4 1.0 CB B:CYS864 3.1 29.9 1.0 CB B:CYS810 3.1 27.4 1.0 CB B:CYS869 3.2 29.1 1.0 CB B:CYS813 3.4 30.4 1.0 N B:CYS813 3.9 29.8 1.0 CA B:CYS813 4.2 29.4 1.0 CZ2 B:TRP873 4.4 30.1 1.0 CB B:HIS871 4.5 28.6 1.0 CA B:CYS864 4.6 29.7 1.0 CA B:CYS810 4.6 30.1 1.0 NE1 B:TRP873 4.6 23.1 1.0 CA B:CYS869 4.7 36.1 1.0 CB B:LYS812 4.7 28.6 1.0 CB B:ARG866 4.8 34.9 1.0 C B:CYS813 4.8 30.1 1.0 CB B:ALA815 4.8 35.2 1.0 CE2 B:TRP873 4.8 25.8 1.0 N B:HIS871 4.9 27.7 1.0 C B:LYS812 5.0 28.5 1.0 CG B:ARG866 5.0 39.4 1.0

A.K.De Regt, K.Anand, K.Gatterdam, G.Hagelueken, G.Hartmann, M.Geyer, M.Schlee. A Conserved Isoleucine in the Rna Sensor Rig-I Controls Immune Tolerance to Mitochondrial Rna To Be Published.