Zinc in PDB 7a08: Cryoem Structure of Cgas Nucleosome Complex

All present enzymatic activity of Cryoem Structure of Cgas Nucleosome Complex:
2.7.7.86;

The binding sites of Zinc atom in the Cryoem Structure of Cgas Nucleosome Complex (pdb code 7a08). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryoem Structure of Cgas Nucleosome Complex, PDB code: 7a08:

Zinc binding site 1 out of 1 in the Cryoem Structure of Cgas Nucleosome Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryoem Structure of Cgas Nucleosome Complex within 5.0Å range: probe atom residue distance (Å) B Occ a:Zn601 b:0.1 occ:1.00 CB a:CYS392 2.1 76.3 1.0 SG a:CYS392 2.3 76.3 1.0 NE a:ARG394 3.1 69.2 1.0 CA a:CYS392 3.2 76.3 1.0 C a:CYS392 3.2 76.3 1.0 CG a:ARG394 3.3 69.2 1.0 CB a:TRP440 3.4 72.2 1.0 N a:CYS393 3.5 77.8 1.0 CD a:ARG394 3.6 69.2 1.0 O a:TRP440 3.7 72.2 1.0 CZ a:ARG394 3.7 69.2 1.0 O a:CYS392 3.7 76.3 1.0 CB a:ARG394 3.8 69.2 1.0 N a:ARG394 3.9 69.2 1.0 CG a:TRP440 4.0 72.2 1.0 NH1 a:ARG394 4.0 69.2 1.0 C a:CYS393 4.1 77.8 1.0 N a:CYS392 4.4 76.3 1.0 CA a:CYS393 4.4 77.8 1.0 CA a:TRP440 4.5 72.2 1.0 CA a:ARG394 4.5 69.2 1.0 C a:TRP440 4.5 72.2 1.0 CD2 a:TRP440 4.5 72.2 1.0 NH2 a:ARG394 4.5 69.2 1.0 O a:CYS393 4.6 77.8 1.0 CD2 a:HIS378 4.6 63.1 1.0 NE2 a:HIS378 4.7 63.1 1.0 CE3 a:TRP440 4.7 72.2 1.0 CD1 a:TRP440 4.8 72.2 1.0 SG a:CYS384 4.8 76.4 1.0 NE2 a:GLN436 5.0 64.6 1.0

S.Michalski, C.C.De Oliveira Mann, C.A.Stafford, G.Witte, J.Bartho, K.Lammens, V.Hornung, K.P.Hopfner. Structural Basis For Sequestration and Autoinhibition of Cgas By Chromatin. Nature V. 587 678 2020.
ISSN: ESSN 1476-4687
PubMed: 32911480
DOI: 10.1038/S41586-020-2748-0