Zinc in PDB 6zw1: X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101

The structure of X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101, PDB code: 6zw1 was solved by C.Barinka, L.Motlova, K.Ustinova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.08 / 1.13
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	83.933, 94.158, 51.487, 90, 90, 90
R / Rfree (%)	14 / 15.9

The structure of X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 also contains other interesting chemical elements:

Potassium

(K)

2 atoms

The binding sites of Zinc atom in the X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 (pdb code 6zw1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101, PDB code: 6zw1:

Zinc binding site 1 out of 1 in the X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2001 b:8.0 occ:0.85 OAD A:QRB2002 1.9 12.3 1.0 OD2 A:ASP705 2.0 8.2 1.0 OD1 A:ASP612 2.0 8.2 1.0 ND1 A:HIS614 2.1 7.7 1.0 OAE A:QRB2002 2.3 11.8 1.0 NAC A:QRB2002 2.6 12.9 1.0 CG A:ASP612 2.7 7.3 1.0 OD2 A:ASP612 2.8 9.2 1.0 CAB A:QRB2002 2.8 12.1 1.0 CG A:ASP705 3.0 7.7 1.0 CE1 A:HIS614 3.0 8.2 1.0 CG A:HIS614 3.2 8.3 1.0 OD1 A:ASP705 3.4 8.6 1.0 CB A:HIS614 3.6 8.1 1.0 N A:HIS614 4.0 7.7 1.0 NE2 A:HIS573 4.1 9.0 1.0 NE2 A:HIS614 4.2 8.8 1.0 CAA A:QRB2002 4.2 11.0 1.0 CB A:ASP612 4.2 6.9 1.0 CD2 A:HIS614 4.3 8.2 1.0 OH A:TYR745 4.3 10.3 1.0 CA A:GLY743 4.3 8.1 1.0 CB A:ASP705 4.3 7.6 1.0 CG1 A:VAL613 4.3 8.0 1.0 CA A:HIS614 4.4 7.7 1.0 N A:VAL613 4.4 7.8 1.0 CE1 A:HIS573 4.5 8.6 1.0 O A:HOH2374 4.5 24.0 1.0 CE2 A:TYR745 4.6 9.2 1.0 N A:GLY743 4.6 7.7 1.0 CAF A:QRB2002 4.7 12.5 1.0 NE2 A:HIS574 4.7 9.2 1.0 C A:VAL613 4.9 8.2 1.0 C A:ASP612 4.9 7.9 1.0 CA A:ASP612 4.9 7.1 1.0 CZ A:TYR745 4.9 9.2 1.0

C.Barinka, L.Motlova, K.Ustinova. X-Ray Structure of Danio Rerio Histone Deacetylase 6 (HDAC6) CD2 in Complex with An Inhibitor SW101 To Be Published.