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Zinc in PDB 6z8k: La Crosse Virus Polymerase at Elongation Mimicking Stage

Enzymatic activity of La Crosse Virus Polymerase at Elongation Mimicking Stage

All present enzymatic activity of La Crosse Virus Polymerase at Elongation Mimicking Stage:
2.7.7.48;

Other elements in 6z8k:

The structure of La Crosse Virus Polymerase at Elongation Mimicking Stage also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the La Crosse Virus Polymerase at Elongation Mimicking Stage (pdb code 6z8k). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the La Crosse Virus Polymerase at Elongation Mimicking Stage, PDB code: 6z8k:

Zinc binding site 1 out of 1 in 6z8k

Go back to Zinc Binding Sites List in 6z8k
Zinc binding site 1 out of 1 in the La Crosse Virus Polymerase at Elongation Mimicking Stage


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of La Crosse Virus Polymerase at Elongation Mimicking Stage within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn2301

b:91.5
occ:1.00
OD1 A:ASP2178 2.1 80.4 1.0
NE2 A:HIS2182 2.3 82.5 1.0
CE1 A:HIS2169 2.4 72.4 1.0
SG A:CYS2064 2.6 77.5 1.0
NE2 A:HIS2169 2.9 72.4 1.0
CB A:CYS2064 2.9 77.5 1.0
CG A:ASP2178 3.0 80.4 1.0
OD2 A:ASP2178 3.1 80.4 1.0
CD2 A:HIS2182 3.2 82.5 1.0
CE1 A:HIS2182 3.2 82.5 1.0
N A:GLY2066 3.6 79.8 1.0
ND1 A:HIS2169 3.6 72.4 1.0
N A:GLU2065 3.9 82.5 1.0
CD1 A:ILE2173 3.9 71.9 1.0
CA A:CYS2064 4.2 77.5 1.0
CD2 A:HIS2169 4.2 72.4 1.0
CG1 A:ILE2173 4.2 71.9 1.0
CA A:GLY2066 4.3 79.8 1.0
C A:CYS2064 4.3 77.5 1.0
ND1 A:HIS2182 4.3 82.5 1.0
CB A:ASP2178 4.4 80.4 1.0
CG A:HIS2182 4.4 82.5 1.0
N A:SER2067 4.4 77.9 1.0
CA A:GLU2065 4.5 82.5 1.0
C A:GLU2065 4.5 82.5 1.0
CG A:HIS2169 4.5 72.4 1.0
N A:CYS2064 4.8 77.5 1.0
C A:GLY2066 4.9 79.8 1.0
O A:ASP2178 4.9 80.4 1.0

Reference:

B.Arragain, G.Effantin, P.Gerlach, J.Reguera, G.Schoehn, S.Cusack, H.Malet. Pre-Initiation and Elongation Structures of Full-Length La Crosse Virus Polymerase Reveal Functionally Important Conformational Changes. Nat Commun V. 11 3590 2020.
ISSN: ESSN 2041-1723
PubMed: 32681014
DOI: 10.1038/S41467-020-17349-4
Page generated: Tue Oct 29 15:33:10 2024

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