Zinc in PDB 6z6g: Cryo-Em Structure of La Crosse Virus Polymerase at Pre-Initiation Stage

All present enzymatic activity of Cryo-Em Structure of La Crosse Virus Polymerase at Pre-Initiation Stage:
2.7.7.48;

The structure of Cryo-Em Structure of La Crosse Virus Polymerase at Pre-Initiation Stage also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of La Crosse Virus Polymerase at Pre-Initiation Stage (pdb code 6z6g). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of La Crosse Virus Polymerase at Pre-Initiation Stage, PDB code: 6z6g:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of La Crosse Virus Polymerase at Pre-Initiation Stage


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of La Crosse Virus Polymerase at Pre-Initiation Stage within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2301 b:91.5 occ:1.00 OD1 A:ASP2178 2.1 80.4 1.0 NE2 A:HIS2182 2.3 82.5 1.0 CE1 A:HIS2169 2.4 72.4 1.0 SG A:CYS2064 2.6 77.5 1.0 NE2 A:HIS2169 2.9 72.4 1.0 CB A:CYS2064 2.9 77.5 1.0 CG A:ASP2178 3.0 80.4 1.0 OD2 A:ASP2178 3.1 80.4 1.0 CD2 A:HIS2182 3.2 82.5 1.0 CE1 A:HIS2182 3.2 82.5 1.0 N A:GLY2066 3.6 79.8 1.0 ND1 A:HIS2169 3.6 72.4 1.0 N A:GLU2065 3.9 82.5 1.0 CD1 A:ILE2173 3.9 71.9 1.0 CA A:CYS2064 4.2 77.5 1.0 CD2 A:HIS2169 4.2 72.4 1.0 CG1 A:ILE2173 4.2 71.9 1.0 CA A:GLY2066 4.3 79.8 1.0 C A:CYS2064 4.3 77.5 1.0 ND1 A:HIS2182 4.3 82.5 1.0 CB A:ASP2178 4.4 80.4 1.0 CG A:HIS2182 4.4 82.5 1.0 N A:SER2067 4.4 77.9 1.0 CA A:GLU2065 4.5 82.5 1.0 C A:GLU2065 4.5 82.5 1.0 CG A:HIS2169 4.5 72.4 1.0 N A:CYS2064 4.8 77.5 1.0 C A:GLY2066 4.9 79.8 1.0 O A:ASP2178 4.9 80.4 1.0

B.Arragain, G.Effantin, P.Gerlach, J.Reguera, G.Schoehn, S.Cusack, H.Malet. Pre-Initiation and Elongation Structures of Full-Length La Crosse Virus Polymerase Reveal Functionally Important Conformational Changes. Nat Commun V. 11 3590 2020.
ISSN: ESSN 2041-1723
PubMed: 32681014
DOI: 10.1038/S41467-020-17349-4