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Zinc in PDB 6ygs: Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-OneEnzymatic activity of Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-One
All present enzymatic activity of Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-One:
2.4.2.29; Protein crystallography data
The structure of Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-One, PDB code: 6ygs
was solved by
A.Nguyen,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ygs:
The structure of Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-One also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-One
(pdb code 6ygs). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-One, PDB code: 6ygs: Zinc binding site 1 out of 1 in 6ygsGo back to Zinc Binding Sites List in 6ygs
Zinc binding site 1 out
of 1 in the Trna-Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(4-(Trifluoromethyl)Phenethyl)-3,7-Dihydro- 8H-Imidazo[4,5-G]Quinazolin-8-One
Mono view Stereo pair view
Reference:
A.Nguyen,
A.Heine,
G.Klebe.
Co-Crystallization and 19F uc(Nmr) Reveal Dimer Disturbing Inhibitors and Conformational Changes at Dimer Contacts To Be Published.
Page generated: Wed Dec 16 13:16:08 2020
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