Zinc in PDB 6tbz: Crystal Structure of the MH1 Domain of SMAD5-SMAD3 Chimera Construct Bound to the Ggcgc Site

The structure of Crystal Structure of the MH1 Domain of SMAD5-SMAD3 Chimera Construct Bound to the Ggcgc Site, PDB code: 6tbz was solved by R.Pluta, M.J.Maicas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.00 / 1.78
Space group	P 32
Cell size a, b, c (Å), α, β, γ (°)	53.145, 53.145, 83.154, 90.00, 90.00, 120.00
R / Rfree (%)	19.2 / 22.6

The binding sites of Zinc atom in the Crystal Structure of the MH1 Domain of SMAD5-SMAD3 Chimera Construct Bound to the Ggcgc Site (pdb code 6tbz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of the MH1 Domain of SMAD5-SMAD3 Chimera Construct Bound to the Ggcgc Site, PDB code: 6tbz:

Zinc binding site 1 out of 1 in the Crystal Structure of the MH1 Domain of SMAD5-SMAD3 Chimera Construct Bound to the Ggcgc Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of the MH1 Domain of SMAD5-SMAD3 Chimera Construct Bound to the Ggcgc Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:27.4 occ:1.00 ND1 A:HIS127 2.0 25.8 1.0 SG A:CYS110 2.1 22.4 1.0 SG A:CYS65 2.5 27.2 1.0 SG A:CYS122 2.5 29.8 1.0 CE1 A:HIS127 2.9 28.0 1.0 CG A:HIS127 3.0 26.0 1.0 CB A:CYS122 3.0 26.6 1.0 CB A:CYS110 3.1 27.3 1.0 CB A:CYS65 3.4 26.9 1.0 CB A:HIS127 3.4 25.3 1.0 CA A:CYS110 3.6 28.4 1.0 CA A:CYS65 3.6 28.0 1.0 NE2 A:HIS127 4.0 28.5 1.0 CD2 A:HIS127 4.1 26.6 1.0 N A:GLU111 4.1 28.6 1.0 C A:CYS110 4.3 29.0 1.0 N A:CYS65 4.4 28.4 1.0 CA A:CYS122 4.5 26.1 1.0 N A:PHE112 4.6 30.0 1.0 N A:CYS110 4.8 29.5 1.0 C A:CYS65 4.8 29.2 1.0 N A:VAL66 4.8 28.9 1.0 CB A:ASN124 4.9 27.2 1.0 CA A:HIS127 4.9 26.3 1.0

L.Ruiz, Z.Kaczmarska, T.Gomes, E.Aragon, C.Torner, R.Freier, B.Baginski, P.Martin-Malpartida, N.Martin Garrido, J.Marquez, T.Cordeiro, R.Pluta, M.J.Macias. Unveiling the Dimer/Monomer Propensities of Smad MH1-Dna Complexes To Be Published.