Zinc in PDB 6gzy: Hoip-FRAGMENT5 Complex

Enzymatic activity of Hoip-FRAGMENT5 Complex

All present enzymatic activity of Hoip-FRAGMENT5 Complex:
2.3.2.27;

Protein crystallography data

The structure of Hoip-FRAGMENT5 Complex, PDB code: 6gzy was solved by H.Johansson, Y.C.I.Tsai, K.Fantom, C.W.Chung, L.Martino, D.House, K.Rittinger, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 80.69 / 2.15
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 111.202, 117.249, 37.940, 90.00, 90.00, 90.00
R / Rfree (%) 19.9 / 24.6

Other elements in 6gzy:

The structure of Hoip-FRAGMENT5 Complex also contains other interesting chemical elements:

Sodium (Na) 2 atoms

Zinc Binding Sites:

The binding sites of Zinc atom in the Hoip-FRAGMENT5 Complex (pdb code 6gzy). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the Hoip-FRAGMENT5 Complex, PDB code: 6gzy:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Zinc binding site 1 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 1 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn4002

b:17.7
occ:1.00
SG A:CYS893 2.2 14.6 1.0
SG A:CYS890 2.3 16.5 1.0
SG A:CYS874 2.3 15.4 1.0
SG A:CYS871 2.4 23.0 1.0
HB3 A:CYS874 2.9 21.5 1.0
H A:CYS874 3.0 24.2 1.0
HB3 A:CYS890 3.0 22.2 1.0
HB3 A:CYS871 3.0 20.8 1.0
CB A:CYS890 3.1 18.6 1.0
CB A:CYS871 3.1 17.3 1.0
CB A:CYS874 3.2 17.9 1.0
HB2 A:CYS871 3.2 20.8 1.0
HB2 A:CYS890 3.2 22.2 1.0
HB3 A:CYS893 3.2 20.4 1.0
H A:CYS893 3.3 27.7 1.0
CB A:CYS893 3.4 17.0 1.0
N A:CYS874 3.6 20.2 1.0
HB2 A:GLN892 3.7 25.0 1.0
HB3 A:LYS873 3.8 30.3 1.0
N A:CYS893 3.8 23.1 1.0
HB3 A:HIS895 3.8 21.9 1.0
CA A:CYS874 3.9 22.9 1.0
HB2 A:CYS874 4.0 21.5 1.0
HB2 A:CYS893 4.1 20.4 1.0
CA A:CYS893 4.2 19.6 1.0
H A:HIS895 4.2 27.3 0.5
H A:HIS895 4.2 27.3 0.5
H A:PHE876 4.2 24.2 1.0
HH A:TYR878 4.3 27.8 1.0
HB3 A:PHE876 4.4 28.2 1.0
H A:LYS873 4.5 30.2 1.0
HB2 A:HIS895 4.5 21.9 1.0
H A:LYS875 4.5 24.5 1.0
H A:GLN892 4.5 22.9 1.0
HB2 A:PHE876 4.5 28.2 1.0
CA A:CYS890 4.6 19.7 1.0
CA A:CYS871 4.6 13.8 1.0
C A:CYS874 4.6 19.5 1.0
CB A:HIS895 4.6 18.3 1.0
CB A:GLN892 4.6 20.8 1.0
CB A:LYS873 4.7 25.2 1.0
HG2 A:LYS873 4.7 35.4 1.0
C A:LYS873 4.7 18.9 1.0
HA A:CYS874 4.8 27.4 1.0
H A:ARG894 4.8 22.1 0.5
N A:LYS875 4.8 20.4 1.0
HD3 A:LYS873 4.8 36.8 1.0
H A:ARG894 4.8 21.8 0.5
C A:CYS893 4.8 15.8 1.0
C A:GLN892 4.8 22.7 1.0
CB A:PHE876 4.9 23.5 1.0
HA A:CYS890 4.9 23.6 1.0
HA A:CYS871 4.9 16.5 1.0
HE1 A:TYR878 4.9 25.4 1.0
HA A:CYS893 5.0 23.5 1.0

Zinc binding site 2 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 2 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn4003

b:16.7
occ:1.00
ND1 A:HIS926 2.0 15.4 1.0
SG A:CYS898 2.2 16.2 1.0
SG A:CYS901 2.3 14.4 1.0
SG A:CYS930 2.3 13.9 1.0
CE1 A:HIS926 2.9 16.1 1.0
HB3 A:HIS926 3.0 22.1 1.0
HE1 A:HIS926 3.1 19.3 1.0
CG A:HIS926 3.1 18.1 1.0
HB3 A:CYS898 3.1 27.7 1.0
H A:CYS901 3.1 15.5 1.0
HB3 A:CYS901 3.2 22.5 1.0
CB A:CYS898 3.2 23.1 1.0
CB A:CYS901 3.3 18.8 1.0
HB2 A:PHE932 3.3 26.2 1.0
HB2 A:CYS898 3.4 27.7 1.0
CB A:HIS926 3.5 18.4 1.0
HB2 A:CYS930 3.5 28.1 1.0
CB A:CYS930 3.5 23.4 1.0
N A:CYS901 3.6 13.0 1.0
HB3 A:PHE932 3.7 26.2 1.0
HB3 A:CYS930 3.7 28.1 1.0
HD2 A:PRO927 3.7 20.3 1.0
HA A:HIS926 3.7 23.3 1.0
CB A:PHE932 4.0 21.9 1.0
H A:GLY900 4.0 14.6 1.0
CA A:CYS901 4.0 18.4 1.0
H A:PHE932 4.0 16.7 1.0
NE2 A:HIS926 4.1 17.6 1.0
HB2 A:CYS901 4.1 22.5 1.0
HA3 A:GLY900 4.1 15.6 1.0
CD2 A:HIS926 4.2 18.6 1.0
HE2 A:MET886 4.2 19.6 0.8
CA A:HIS926 4.2 19.4 1.0
HB2 A:HIS926 4.3 22.1 1.0
C A:GLY900 4.3 12.7 1.0
CA A:GLY900 4.5 13.0 1.0
CA A:CYS898 4.6 19.4 1.0
N A:GLY900 4.6 12.2 1.0
HB2 A:ASN903 4.6 21.2 1.0
CD A:PRO927 4.7 16.9 1.0
H A:ASN903 4.7 21.6 1.0
HD22 A:ASN903 4.8 23.8 1.0
H A:TYR902 4.8 20.4 1.0
HA A:CYS901 4.8 22.0 1.0
N A:PHE932 4.8 13.9 1.0
HE3 A:MET886 4.8 19.6 0.8
HE2 A:HIS926 4.8 21.0 1.0
CG A:PHE932 4.8 17.4 1.0
HB3 A:MET886 4.9 24.8 0.8
CA A:CYS930 4.9 14.7 1.0
C A:CYS901 4.9 15.5 1.0
HB3 A:MET886 4.9 25.2 0.2
CE A:MET886 4.9 16.3 0.8
O A:HIS925 4.9 19.7 1.0
C A:CYS898 5.0 17.5 1.0
HA A:CYS898 5.0 23.2 1.0

Zinc binding site 3 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 3 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn4004

b:35.8
occ:1.00
NE2 A:HIS923 2.0 28.9 1.0
NE2 A:HIS925 2.2 29.8 1.0
SG A:CYS911 2.2 40.2 1.0
SG A:CYS916 2.3 42.3 1.0
HB2 A:CYS916 2.7 59.4 1.0
CE1 A:HIS923 2.9 29.6 1.0
HE1 A:HIS923 3.0 35.4 1.0
CB A:CYS916 3.0 49.6 1.0
CD2 A:HIS925 3.0 31.4 1.0
HD2 A:HIS925 3.1 37.7 1.0
CD2 A:HIS923 3.1 30.5 1.0
CB A:CYS911 3.2 54.0 1.0
HB2 A:CYS911 3.2 64.8 1.0
CE1 A:HIS925 3.2 35.1 1.0
HB3 A:CYS911 3.3 64.8 1.0
HB3 A:GLU913 3.4 94.4 1.0
HD2 A:HIS923 3.4 36.5 1.0
HB3 A:CYS916 3.4 59.4 1.0
HE1 A:HIS925 3.5 42.0 1.0
HB2 A:GLU913 3.7 94.4 1.0
CB A:GLU913 4.0 78.7 1.0
ND1 A:HIS923 4.1 28.5 1.0
HA A:LYS919 4.1 66.0 1.0
CG A:HIS923 4.2 29.4 1.0
CG A:HIS925 4.2 29.4 1.0
ND1 A:HIS925 4.3 28.5 1.0
HG2 A:GLU913 4.3 0.2 1.0
CA A:CYS916 4.3 55.5 1.0
HA A:CYS916 4.4 66.5 1.0
H A:GLU913 4.5 83.2 1.0
CA A:CYS911 4.6 53.7 1.0
HD2 A:TYR906 4.6 50.5 1.0
H A:VAL918 4.6 83.8 1.0
CG A:GLU913 4.7 86.8 1.0
HD1 A:HIS923 4.8 34.2 1.0
HA A:CYS911 4.8 64.4 1.0
HB A:VAL918 4.9 80.1 1.0
CA A:LYS919 5.0 55.0 1.0

Zinc binding site 4 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 4 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn4005

b:36.5
occ:1.00
ND1 A:HIS1001 2.0 18.7 1.0
SG A:CYS998 2.2 31.7 1.0
SG A:CYS986 2.4 52.2 1.0
SG A:CYS969 2.4 53.0 1.0
HB3 A:CYS969 2.7 59.2 1.0
CE1 A:HIS1001 2.8 21.7 1.0
HE1 A:HIS1001 2.9 26.0 1.0
CB A:CYS969 3.0 49.4 1.0
HB2 A:CYS969 3.1 59.2 1.0
HB2 A:HIS1001 3.1 27.3 1.0
HB3 A:CYS998 3.2 42.1 1.0
CG A:HIS1001 3.2 21.4 1.0
HB3 A:CYS986 3.2 64.6 1.0
H A:CYS998 3.3 53.0 1.0
CB A:CYS998 3.3 35.1 1.0
CB A:CYS986 3.3 53.9 1.0
HB2 A:CYS986 3.5 64.6 1.0
CB A:HIS1001 3.7 22.8 1.0
HB A:VAL971 3.8 38.1 1.0
HB2 A:LYS988 3.9 54.4 1.0
HG23 A:VAL971 4.0 39.4 1.0
H A:HIS1001 4.0 24.7 1.0
NE2 A:HIS1001 4.0 19.0 1.0
N A:CYS998 4.0 44.2 1.0
HB2 A:CYS998 4.0 42.1 1.0
CD2 A:HIS1001 4.2 18.3 1.0
H A:LYS988 4.2 62.6 1.0
HB3 A:HIS1001 4.3 27.3 1.0
CA A:CYS998 4.3 39.5 1.0
CA A:CYS969 4.4 53.1 1.0
H A:VAL971 4.5 48.7 1.0
CB A:VAL971 4.6 31.8 1.0
CG2 A:VAL971 4.6 32.9 1.0
HD22 A:LEU997 4.6 40.0 1.0
N A:HIS1001 4.7 20.6 1.0
HB3 A:LEU997 4.7 39.5 1.0
HZ3 A:LYS988 4.8 62.9 1.0
HE2 A:HIS1001 4.8 22.8 1.0
HG21 A:VAL971 4.8 39.4 1.0
O A:HOH4118 4.8 35.3 1.0
CA A:CYS986 4.8 56.8 1.0
CA A:HIS1001 4.8 24.5 1.0
CB A:LYS988 4.9 45.4 1.0
HA A:CYS969 4.9 63.6 1.0
C A:CYS969 4.9 49.1 1.0
OE2 A:GLU973 4.9 69.5 1.0
H A:GLY987 5.0 51.8 1.0
H A:CYS969 5.0 79.5 1.0
HA A:LEU997 5.0 48.0 1.0

Zinc binding site 5 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 5 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn4002

b:23.0
occ:1.00
SG B:CYS893 2.2 23.4 1.0
SG B:CYS871 2.3 21.1 1.0
SG B:CYS890 2.3 23.1 1.0
SG B:CYS874 2.3 25.4 1.0
HB3 B:CYS874 2.9 31.9 1.0
H B:CYS874 2.9 29.8 1.0
HB3 B:CYS871 3.1 25.2 1.0
HB3 B:CYS890 3.1 25.5 1.0
CB B:CYS871 3.1 21.0 1.0
CB B:CYS874 3.1 26.6 1.0
CB B:CYS890 3.2 21.3 1.0
HB2 B:CYS871 3.2 25.2 1.0
HB2 B:CYS890 3.3 25.5 1.0
HB3 B:CYS893 3.3 30.5 1.0
H B:CYS893 3.3 30.1 1.0
CB B:CYS893 3.4 25.4 1.0
N B:CYS874 3.6 24.9 1.0
HB2 B:GLN892 3.7 32.5 1.0
HB3 B:LYS873 3.8 30.6 1.0
HB3 B:HIS895 3.9 24.2 1.0
N B:CYS893 3.9 25.1 1.0
CA B:CYS874 3.9 26.4 1.0
HB2 B:CYS874 3.9 31.9 1.0
HB2 B:CYS893 4.1 30.5 1.0
H B:PHE876 4.2 37.1 1.0
CA B:CYS893 4.2 26.5 1.0
H B:HIS895 4.2 24.4 0.4
H B:HIS895 4.2 24.4 0.6
H B:LYS873 4.4 34.7 1.0
HB3 B:PHE876 4.4 32.3 1.0
H B:LYS875 4.4 32.5 1.0
HB2 B:HIS895 4.5 24.2 1.0
HH B:TYR878 4.5 33.7 1.0
HB2 B:PHE876 4.5 32.3 1.0
CA B:CYS871 4.6 20.1 1.0
C B:CYS874 4.6 27.1 1.0
H B:GLN892 4.6 29.6 1.0
CB B:HIS895 4.6 20.2 1.0
CA B:CYS890 4.6 20.8 1.0
CB B:LYS873 4.6 25.5 1.0
CB B:GLN892 4.7 27.1 1.0
HG2 B:LYS873 4.7 39.5 1.0
C B:LYS873 4.7 29.9 1.0
N B:LYS875 4.7 27.1 1.0
HA B:CYS874 4.7 31.7 1.0
H B:ARG894 4.8 33.0 1.0
C B:CYS893 4.8 23.9 1.0
HD3 B:LYS873 4.8 41.4 1.0
C B:GLN892 4.8 26.5 1.0
HA B:CYS871 4.9 24.1 1.0
CB B:PHE876 4.9 26.9 1.0
HE1 B:TYR878 4.9 27.8 1.0
HA B:CYS890 5.0 25.0 1.0
N B:LYS873 5.0 28.9 1.0

Zinc binding site 6 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 6 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn4003

b:14.4
occ:1.00
ND1 B:HIS926 2.1 18.0 1.0
SG B:CYS901 2.2 14.0 1.0
SG B:CYS930 2.2 12.9 1.0
SG B:CYS898 2.3 16.4 1.0
HB3 B:HIS926 2.9 22.5 1.0
CE1 B:HIS926 3.0 15.9 1.0
HB3 B:CYS901 3.0 18.6 1.0
CG B:HIS926 3.1 15.5 1.0
H B:CYS901 3.1 16.4 1.0
HB3 B:CYS898 3.2 25.8 1.0
HE1 B:HIS926 3.2 19.1 1.0
CB B:CYS901 3.2 15.6 1.0
CB B:CYS898 3.3 21.5 1.0
HB2 B:PHE932 3.3 19.9 1.0
CB B:HIS926 3.5 18.8 1.0
CB B:CYS930 3.5 16.4 1.0
HB2 B:CYS898 3.5 25.8 1.0
HB2 B:CYS930 3.5 19.6 1.0
N B:CYS901 3.5 13.7 1.0
HD2 B:PRO927 3.6 17.9 1.0
HB3 B:PHE932 3.6 19.9 1.0
HB3 B:CYS930 3.7 19.6 1.0
HA B:HIS926 3.7 28.6 1.0
CB B:PHE932 3.9 16.6 1.0
CA B:CYS901 4.0 14.2 1.0
HB2 B:CYS901 4.0 18.6 1.0
H B:PHE932 4.0 14.9 1.0
H B:GLY900 4.0 15.8 1.0
HA3 B:GLY900 4.1 15.8 1.0
CA B:HIS926 4.1 23.9 1.0
NE2 B:HIS926 4.1 17.5 1.0
CD2 B:HIS926 4.2 14.8 1.0
HE2 B:MET886 4.2 25.1 0.8
HB2 B:HIS926 4.3 22.5 1.0
C B:GLY900 4.3 13.5 1.0
CA B:GLY900 4.5 13.2 1.0
CD B:PRO927 4.5 14.9 1.0
N B:GLY900 4.7 13.2 1.0
CA B:CYS898 4.7 18.5 1.0
HB2 B:ASN903 4.7 22.1 1.0
HA B:CYS901 4.7 17.0 1.0
H B:ASN903 4.8 29.8 1.0
H B:TYR902 4.8 22.9 1.0
N B:PHE932 4.8 12.4 1.0
HD22 B:ASN903 4.8 28.7 1.0
CA B:CYS930 4.8 15.0 1.0
CG B:PHE932 4.8 13.2 1.0
C B:CYS901 4.8 14.8 1.0
HD3 B:PRO927 4.9 17.9 1.0
HE2 B:HIS926 4.9 21.0 1.0
O B:HIS925 4.9 22.2 1.0
HE3 B:MET886 4.9 25.1 0.8
HB3 B:MET886 4.9 18.5 0.8
HA B:CYS930 4.9 17.9 1.0
HB3 B:MET886 5.0 18.4 0.2
C B:CYS898 5.0 18.0 1.0

Zinc binding site 7 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 7 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn4004

b:35.1
occ:1.00
NE2 B:HIS923 2.0 20.5 1.0
NE2 B:HIS925 2.2 28.2 1.0
SG B:CYS911 2.2 31.7 1.0
SG B:CYS916 2.3 42.5 1.0
HB2 B:CYS916 2.7 55.4 1.0
CE1 B:HIS923 3.0 21.0 1.0
CD2 B:HIS925 3.0 29.9 1.0
CB B:CYS916 3.1 46.2 1.0
CD2 B:HIS923 3.1 22.7 1.0
HD2 B:HIS925 3.1 35.9 1.0
HB2 B:CYS911 3.1 47.4 1.0
HE1 B:HIS923 3.1 25.1 1.0
CB B:CYS911 3.2 39.5 1.0
CE1 B:HIS925 3.2 32.0 1.0
HD2 B:HIS923 3.3 27.2 1.0
HB3 B:CYS911 3.3 47.4 1.0
HE1 B:HIS925 3.5 38.4 1.0
HB3 B:CYS916 3.5 55.4 1.0
HB3 B:GLU913 3.5 88.4 1.0
HB2 B:GLU913 3.8 88.4 1.0
ND1 B:HIS923 4.1 24.8 1.0
CB B:GLU913 4.2 73.7 1.0
CG B:HIS923 4.2 20.9 1.0
CG B:HIS925 4.2 29.4 1.0
ND1 B:HIS925 4.3 29.6 1.0
HA B:LYS919 4.3 75.0 1.0
HA B:CYS916 4.3 74.3 1.0
CA B:CYS916 4.3 61.9 1.0
HD2 B:TYR906 4.5 55.0 1.0
HG2 B:GLU913 4.6 97.3 1.0
CA B:CYS911 4.6 48.1 1.0
H B:VAL918 4.6 93.9 1.0
H B:GLU913 4.6 82.6 1.0
HA B:CYS911 4.7 57.7 1.0
HD1 B:HIS923 4.9 29.8 1.0
HB B:VAL918 4.9 84.0 1.0
CG B:GLU913 5.0 81.2 1.0

Zinc binding site 8 out of 8 in 6gzy

Go back to Zinc Binding Sites List in 6gzy
Zinc binding site 8 out of 8 in the Hoip-FRAGMENT5 Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Hoip-FRAGMENT5 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn4005

b:40.0
occ:1.00
ND1 B:HIS1001 1.9 26.7 1.0
SG B:CYS969 2.2 40.5 1.0
SG B:CYS998 2.2 39.3 1.0
SG B:CYS986 2.6 51.5 1.0
CE1 B:HIS1001 2.6 26.7 1.0
HE1 B:HIS1001 2.6 32.0 1.0
HB3 B:CYS969 2.8 58.0 1.0
HB3 B:CYS986 2.9 57.1 1.0
HB3 B:CYS998 2.9 33.7 1.0
CB B:CYS969 3.0 48.3 1.0
CG B:HIS1001 3.1 26.4 1.0
CB B:CYS986 3.2 47.6 1.0
HB2 B:CYS969 3.2 58.0 1.0
H B:CYS998 3.2 43.9 1.0
CB B:CYS998 3.2 28.1 1.0
HB2 B:HIS1001 3.2 35.4 1.0
HB2 B:CYS986 3.3 57.1 1.0
HB B:VAL971 3.5 57.1 1.0
HG23 B:VAL971 3.6 52.9 1.0
CB B:HIS1001 3.7 29.5 1.0
HB2 B:LYS988 3.8 49.1 1.0
NE2 B:HIS1001 3.8 26.5 1.0
HB2 B:CYS998 3.9 33.7 1.0
N B:CYS998 3.9 36.6 1.0
CD2 B:HIS1001 4.1 21.7 1.0
H B:HIS1001 4.1 29.2 1.0
CA B:CYS998 4.2 29.0 1.0
H B:VAL971 4.2 55.2 1.0
H B:LYS988 4.2 60.9 1.0
HB3 B:HIS1001 4.3 35.4 1.0
CG2 B:VAL971 4.3 44.1 1.0
CB B:VAL971 4.3 47.7 1.0
CA B:CYS969 4.4 57.6 1.0
HG21 B:VAL971 4.4 52.9 1.0
HE2 B:HIS1001 4.5 31.7 1.0
CA B:CYS986 4.6 54.3 1.0
HD2 B:LYS988 4.7 55.8 1.0
CB B:LYS988 4.7 40.9 1.0
HB3 B:LEU997 4.8 43.6 1.0
N B:HIS1001 4.8 24.4 1.0
HG3 B:LYS988 4.8 52.8 1.0
HA B:CYS969 4.8 69.1 1.0
H B:GLY987 4.8 68.5 1.0
C B:CYS969 4.9 57.5 1.0
HA B:CYS998 4.9 34.8 1.0
CA B:HIS1001 4.9 27.0 1.0
HD22 B:LEU997 4.9 49.8 1.0
N B:VAL971 5.0 46.0 1.0
HD2 B:HIS1001 5.0 26.0 1.0
HA B:LEU997 5.0 47.7 1.0
C B:CYS998 5.0 36.6 1.0

Reference:

H.Johansson, Y.C.Isabella Tsai, K.Fantom, C.W.Chung, S.Kumper, L.Martino, D.A.Thomas, H.C.Eberl, M.Muelbaier, D.House, K.Rittinger. Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors For the Rbr E3 Ubiquitin Ligase Hoip. J. Am. Chem. Soc. V. 141 2703 2019.
ISSN: ESSN 1520-5126
PubMed: 30657686
DOI: 10.1021/JACS.8B13193
Page generated: Wed Dec 16 11:53:58 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy