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Atomistry » Zinc » PDB 5lku-5lrj » 5lpo » |
Zinc in PDB 5lpo: Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5- Trimethoxytetrahydrofuran-2-Yl)Ethyl)-1H-Imidazo[4,5-G]Quinazolin- 8(7H)-OneEnzymatic activity of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5- Trimethoxytetrahydrofuran-2-Yl)Ethyl)-1H-Imidazo[4,5-G]Quinazolin- 8(7H)-One
All present enzymatic activity of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5- Trimethoxytetrahydrofuran-2-Yl)Ethyl)-1H-Imidazo[4,5-G]Quinazolin- 8(7H)-One:
2.4.2.29; Protein crystallography data
The structure of Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5- Trimethoxytetrahydrofuran-2-Yl)Ethyl)-1H-Imidazo[4,5-G]Quinazolin- 8(7H)-One, PDB code: 5lpo
was solved by
F.R.Ehrmann,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5- Trimethoxytetrahydrofuran-2-Yl)Ethyl)-1H-Imidazo[4,5-G]Quinazolin- 8(7H)-One
(pdb code 5lpo). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5- Trimethoxytetrahydrofuran-2-Yl)Ethyl)-1H-Imidazo[4,5-G]Quinazolin- 8(7H)-One, PDB code: 5lpo: Zinc binding site 1 out of 1 in 5lpoGo back to![]() ![]()
Zinc binding site 1 out
of 1 in the Trna Guanine Transglycosylase (Tgt) in Co-Crystallized Complex with 6- Amino-2-(Methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5- Trimethoxytetrahydrofuran-2-Yl)Ethyl)-1H-Imidazo[4,5-G]Quinazolin- 8(7H)-One
![]() Mono view ![]() Stereo pair view
Reference:
F.R.Ehrmann,
T.Botzanowski,
T.Pfaffender,
A.Heine,
F.Diederich,
S.Sanglier-Cianferani,
G.Klebe.
Carbohydrate-Based Inhibitors Targeting the Ribose-34 Pocket of Z.Mobilis Tgt and Changing the Oligomeric State of the Homodimer To Be Published.
Page generated: Wed Dec 16 06:30:24 2020
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