Zinc in PDB 1xox: Solution Structure of Human Survivin

The binding sites of Zinc atom in the Solution Structure of Human Survivin (pdb code 1xox). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Solution Structure of Human Survivin, PDB code: 1xox:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Solution Structure of Human Survivin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Solution Structure of Human Survivin within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn998 b:0.7 occ:1.00 HE1 B:HIS77 2.0 1.1 1.0 SG B:CYS57 2.1 1.0 1.0 SG B:CYS60 2.1 0.8 1.0 SG B:CYS84 2.1 1.1 1.0 CE1 B:HIS77 2.1 0.9 1.0 ND1 B:HIS77 2.2 0.6 1.0 HB2 B:CYS84 3.0 1.1 1.0 HB3 B:CYS57 3.1 0.7 1.0 NE2 B:HIS77 3.1 1.2 1.0 CB B:CYS84 3.2 1.1 1.0 O B:PHE58 3.2 1.5 1.0 CG B:HIS77 3.3 0.7 1.0 CB B:CYS57 3.3 0.8 1.0 HB3 B:CYS60 3.5 0.7 1.0 CB B:CYS60 3.5 0.7 1.0 HA3 B:GLY42 3.6 0.7 1.0 CD2 B:HIS77 3.7 1.0 1.0 HE2 B:HIS77 3.8 1.5 1.0 O B:ALA41 3.8 1.1 1.0 HB2 B:CYS57 3.9 1.0 1.0 H B:CYS84 3.9 1.0 1.0 HB3 B:CYS84 3.9 1.1 1.0 HB2 B:CYS60 4.0 0.7 1.0 N B:CYS84 4.1 1.1 1.0 CA B:CYS84 4.1 1.1 1.0 HB2 B:HIS77 4.2 1.1 1.0 HE1 B:PHE86 4.3 2.0 1.0 CB B:HIS77 4.3 0.7 1.0 HA B:CYS84 4.3 1.1 1.0 C B:CYS57 4.4 0.5 1.0 HB3 B:PHE59 4.4 0.8 1.0 C B:PHE58 4.4 0.6 1.0 HD21 B:LEU87 4.4 0.9 1.0 CA B:CYS57 4.4 0.7 1.0 HD23 B:LEU87 4.4 0.8 1.0 H B:PHE61 4.5 0.6 1.0 N B:PHE58 4.5 0.4 1.0 HD13 B:LEU87 4.5 0.8 1.0 HB3 B:HIS77 4.6 0.7 1.0 H B:PHE58 4.6 0.4 1.0 CA B:GLY42 4.6 0.6 1.0 CA B:CYS60 4.7 0.6 1.0 N B:CYS60 4.7 0.7 1.0 HD2 B:HIS77 4.7 1.2 1.0 O B:CYS57 4.7 0.5 1.0 C B:PHE59 4.7 0.7 1.0 O B:PHE59 4.8 1.4 1.0 HA B:CYS57 4.8 0.8 1.0 CD2 B:LEU87 4.9 0.6 1.0 C B:GLY83 4.9 1.3 1.0 C B:ALA41 4.9 0.9 1.0 C B:GLY42 4.9 0.6 1.0 HD1 B:PHE58 5.0 2.1 1.0

Zinc binding site 2 out of 2 in the Solution Structure of Human Survivin


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Solution Structure of Human Survivin within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn999 b:0.7 occ:1.00 HE1 A:HIS77 2.0 1.1 1.0 SG A:CYS57 2.1 1.0 1.0 SG A:CYS60 2.1 0.8 1.0 SG A:CYS84 2.1 1.1 1.0 CE1 A:HIS77 2.1 0.9 1.0 ND1 A:HIS77 2.2 0.6 1.0 HB2 A:CYS84 3.0 1.1 1.0 HB3 A:CYS57 3.1 0.7 1.0 NE2 A:HIS77 3.1 1.2 1.0 CB A:CYS84 3.2 1.1 1.0 O A:PHE58 3.2 1.5 1.0 CG A:HIS77 3.3 0.7 1.0 CB A:CYS57 3.3 0.8 1.0 HB3 A:CYS60 3.5 0.7 1.0 CB A:CYS60 3.5 0.7 1.0 HA3 A:GLY42 3.6 0.7 1.0 CD2 A:HIS77 3.7 1.0 1.0 HE2 A:HIS77 3.8 1.5 1.0 O A:ALA41 3.8 1.1 1.0 HB2 A:CYS57 3.9 1.0 1.0 H A:CYS84 3.9 1.0 1.0 HB3 A:CYS84 3.9 1.1 1.0 HB2 A:CYS60 4.0 0.7 1.0 N A:CYS84 4.1 1.1 1.0 CA A:CYS84 4.1 1.1 1.0 HB2 A:HIS77 4.2 1.1 1.0 HE1 A:PHE86 4.3 2.0 1.0 CB A:HIS77 4.3 0.7 1.0 HA A:CYS84 4.3 1.1 1.0 HB3 A:PHE59 4.4 0.8 1.0 C A:CYS57 4.4 0.5 1.0 C A:PHE58 4.4 0.6 1.0 HD21 A:LEU87 4.4 0.9 1.0 CA A:CYS57 4.4 0.7 1.0 HD23 A:LEU87 4.4 0.8 1.0 H A:PHE61 4.5 0.6 1.0 N A:PHE58 4.5 0.4 1.0 HD13 A:LEU87 4.5 0.8 1.0 HB3 A:HIS77 4.6 0.7 1.0 H A:PHE58 4.6 0.4 1.0 CA A:GLY42 4.6 0.6 1.0 CA A:CYS60 4.7 0.6 1.0 N A:CYS60 4.7 0.7 1.0 HD2 A:HIS77 4.7 1.2 1.0 O A:CYS57 4.7 0.5 1.0 C A:PHE59 4.7 0.7 1.0 O A:PHE59 4.8 1.4 1.0 HA A:CYS57 4.8 0.8 1.0 C A:GLY83 4.9 1.3 1.0 CD2 A:LEU87 4.9 0.6 1.0 C A:ALA41 4.9 0.9 1.0 C A:GLY42 4.9 0.6 1.0 HD1 A:PHE58 5.0 2.1 1.0

C.Sun, D.Nettesheim, Z.Liu, E.T.Olejniczak. Solution Structure of Human Survivin and Its Binding Interface with Smac/Diablo Biochemistry V. 44 11 2005.
ISSN: ISSN 0006-2960
PubMed: 15628841
DOI: 10.1021/BI0485171