Atomistry » Zinc » PDB 1kzo-1lfw » 1lat
Atomistry »
  Zinc »
    PDB 1kzo-1lfw »
      1lat »

Zinc in PDB 1lat: Glucocorticoid Receptor Mutant/Dna Complex

Protein crystallography data

The structure of Glucocorticoid Receptor Mutant/Dna Complex, PDB code: 1lat was solved by D.T.Gewirth, P.B.Sigler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 6.00 / 1.90
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 38.720, 76.070, 118.880, 90.00, 90.00, 90.00
R / Rfree (%) 19.5 / 28.1

Zinc Binding Sites:

The binding sites of Zinc atom in the Glucocorticoid Receptor Mutant/Dna Complex (pdb code 1lat). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Glucocorticoid Receptor Mutant/Dna Complex, PDB code: 1lat:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in 1lat

Go back to Zinc Binding Sites List in 1lat
Zinc binding site 1 out of 4 in the Glucocorticoid Receptor Mutant/Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Glucocorticoid Receptor Mutant/Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1514

b:34.1
occ:1.00
SG A:CYS460 2.3 31.3 1.0
SG A:CYS443 2.3 32.0 1.0
SG A:CYS457 2.4 30.0 1.0
SG A:CYS440 2.4 34.1 1.0
CB A:CYS460 3.3 32.0 1.0
CB A:CYS440 3.4 31.3 1.0
CB A:CYS443 3.4 32.1 1.0
CB A:CYS457 3.7 32.0 1.0
N A:CYS443 3.9 35.5 1.0
N A:CYS457 4.0 37.4 1.0
NH1 A:ARG489 4.0 33.1 1.0
CA A:CYS443 4.2 34.2 1.0
N A:CYS460 4.3 29.3 1.0
CB A:ASP445 4.3 42.9 1.0
CA A:CYS460 4.4 28.0 1.0
CA A:CYS457 4.4 33.1 1.0
CB A:VAL442 4.6 29.5 1.0
C A:VAL442 4.7 36.3 1.0
C A:CYS443 4.7 35.7 1.0
N A:ASP445 4.8 40.5 1.0
CA A:CYS440 4.8 34.6 1.0
NH2 A:ARG496 4.8 25.0 1.0
CB A:THR456 4.9 42.5 1.0
C A:CYS457 4.9 33.8 1.0
N A:SER444 5.0 37.7 1.0
CZ A:ARG489 5.0 30.9 1.0
O A:CYS457 5.0 32.0 1.0

Zinc binding site 2 out of 4 in 1lat

Go back to Zinc Binding Sites List in 1lat
Zinc binding site 2 out of 4 in the Glucocorticoid Receptor Mutant/Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Glucocorticoid Receptor Mutant/Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn1515

b:50.8
occ:1.00
SG A:CYS482 2.2 47.4 1.0
SG A:CYS476 2.3 54.3 1.0
SG A:CYS495 2.3 51.4 1.0
SG A:CYS492 2.3 47.4 1.0
CB A:CYS482 3.2 49.6 1.0
CB A:CYS492 3.2 43.0 1.0
CB A:CYS476 3.3 60.0 1.0
CB A:CYS495 3.4 48.3 1.0
N A:CYS495 4.2 40.9 1.0
N A:CYS482 4.2 56.5 1.0
N A:GLY480 4.2 73.1 1.0
CA A:CYS495 4.3 45.3 1.0
CA A:CYS482 4.3 50.9 1.0
CA A:CYS476 4.4 64.3 1.0
N A:GLU479 4.5 81.8 1.0
O A:HOH199 4.5 47.9 1.0
CA A:GLY480 4.6 68.3 1.0
CA A:CYS492 4.6 44.0 1.0
C A:GLU479 4.7 76.9 1.0
CB A:TYR478 4.7 82.3 1.0
N A:LYS481 4.8 62.2 1.0
NH2 A:ARG498 4.8 67.6 1.0
CA A:GLU479 4.8 79.5 1.0
N A:LYS477 4.9 70.7 1.0
O A:CYS492 5.0 45.4 1.0

Zinc binding site 3 out of 4 in 1lat

Go back to Zinc Binding Sites List in 1lat
Zinc binding site 3 out of 4 in the Glucocorticoid Receptor Mutant/Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Glucocorticoid Receptor Mutant/Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1514

b:33.4
occ:1.00
SG B:CYS457 2.3 31.3 1.0
SG B:CYS443 2.3 35.1 1.0
SG B:CYS460 2.3 29.4 1.0
SG B:CYS440 2.4 35.1 1.0
CB B:CYS440 3.2 36.0 1.0
CB B:CYS460 3.4 30.6 1.0
CB B:CYS457 3.4 33.7 1.0
CB B:CYS443 3.4 30.6 1.0
NH1 B:ARG489 3.7 40.5 1.0
N B:CYS443 3.8 35.4 1.0
N B:CYS457 3.9 35.3 1.0
CA B:CYS443 4.1 35.0 1.0
N B:CYS460 4.2 28.9 1.0
CA B:CYS457 4.3 28.6 1.0
CA B:CYS460 4.4 28.1 1.0
CB B:ASP445 4.4 43.8 1.0
CB B:VAL442 4.5 34.7 1.0
N B:SER444 4.7 41.5 1.0
N B:ASP445 4.7 42.0 1.0
C B:CYS443 4.7 37.7 1.0
C B:VAL442 4.7 34.9 1.0
CA B:CYS440 4.7 40.9 1.0
CZ B:ARG489 4.8 37.4 1.0
NH2 B:ARG496 4.8 17.3 1.0
C B:CYS457 4.9 27.4 1.0
CA B:VAL442 5.0 36.0 1.0
C B:THR456 5.0 37.4 1.0
O B:CYS457 5.0 26.2 1.0

Zinc binding site 4 out of 4 in 1lat

Go back to Zinc Binding Sites List in 1lat
Zinc binding site 4 out of 4 in the Glucocorticoid Receptor Mutant/Dna Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Glucocorticoid Receptor Mutant/Dna Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn1515

b:34.7
occ:1.00
SG B:CYS492 2.3 34.6 1.0
SG B:CYS482 2.3 38.8 1.0
SG B:CYS495 2.3 33.3 1.0
SG B:CYS476 2.4 43.3 1.0
CB B:CYS492 3.3 32.9 1.0
CB B:CYS482 3.4 35.7 1.0
CB B:CYS495 3.4 29.5 1.0
CB B:CYS476 3.4 35.7 1.0
CD1 B:TYR478 3.9 54.1 1.0
N B:CYS482 4.0 39.2 1.0
N B:CYS495 4.1 29.0 1.0
CA B:CYS476 4.2 38.5 1.0
O B:HOH183 4.3 40.2 1.0
CA B:CYS482 4.3 36.3 1.0
CA B:GLY480 4.3 45.2 1.0
CA B:CYS495 4.3 29.8 1.0
N B:LYS481 4.4 44.3 1.0
N B:GLY480 4.5 46.6 1.0
CE1 B:TYR478 4.5 55.3 1.0
O B:HOH274 4.5 26.5 1.0
C B:GLY480 4.7 44.5 1.0
CA B:CYS492 4.8 33.9 1.0
CG B:TYR478 4.8 52.6 1.0
CB B:TYR478 4.8 51.5 1.0
O B:HOH149 4.9 70.6 1.0
O B:HOH148 5.0 42.9 1.0
C B:CYS476 5.0 41.1 1.0
O B:CYS492 5.0 31.6 1.0
N B:TYR478 5.0 47.3 1.0

Reference:

D.T.Gewirth, P.B.Sigler. The Basis For Half-Site Specificity Explored Through A Non-Cognate Steroid Receptor-Dna Complex. Nat.Struct.Biol. V. 2 386 1995.
ISSN: ISSN 1072-8368
PubMed: 7664096
DOI: 10.1038/NSB0595-386
Page generated: Wed Dec 16 02:56:04 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy