Zinc in PDB 8yjx: Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni

All present enzymatic activity of Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni:
3.4.16.4;

The structure of Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni, PDB code: 8yjx was solved by H.J.Choi, D.W.Ki, S.I.Yoon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.79 / 2.95
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	119.867, 119.867, 274.058, 90, 90, 120
R / Rfree (%)	23.5 / 27.9

The binding sites of Zinc atom in the Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni (pdb code 8yjx). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni, PDB code: 8yjx:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn701 b:68.3 occ:1.00 ND1 A:HIS355 2.0 71.7 1.0 SG A:CYS368 2.2 75.8 1.0 SG A:CYS336 2.4 82.2 1.0 SG A:CYS349 2.5 78.1 1.0 CB A:CYS368 2.9 82.2 1.0 CE1 A:HIS355 2.9 72.1 1.0 CG A:HIS355 3.0 71.6 1.0 CA A:CYS368 3.4 75.6 1.0 CB A:HIS355 3.4 77.0 1.0 CB A:CYS336 3.5 85.5 1.0 CB A:CYS349 3.6 63.6 1.0 N A:ASP369 3.9 63.2 1.0 NE2 A:HIS355 4.0 77.4 1.0 C A:CYS368 4.0 65.8 1.0 CD2 A:HIS355 4.0 74.3 1.0 N A:VAL370 4.1 73.2 1.0 CB A:VAL370 4.1 65.8 1.0 N A:HIS355 4.2 84.5 1.0 CG2 A:VAL370 4.2 67.8 1.0 CA A:HIS355 4.4 91.7 1.0 N A:CYS368 4.6 79.9 1.0 CA A:VAL370 4.8 72.8 1.0 CA A:CYS336 4.9 87.5 1.0 CA A:CYS349 5.0 62.2 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Penicillin-Binding Protein 2 (PBP2) From Campylobacter Jejuni within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn701 b:108.1 occ:1.00 SG B:CYS368 2.4 99.2 1.0 SG B:CYS336 2.5 121.4 1.0 ND1 B:HIS355 2.6 123.5 1.0 CG B:HIS355 3.1 129.7 1.0 CB B:CYS368 3.1 104.6 1.0 CA B:CYS368 3.4 109.0 1.0 CB B:HIS355 3.4 130.5 1.0 CE1 B:HIS355 3.4 119.1 1.0 N B:ASP369 3.7 106.2 1.0 CB B:CYS336 3.8 128.2 1.0 C B:CYS368 3.8 112.1 1.0 N B:VAL370 3.9 106.3 1.0 CD2 B:HIS355 4.0 120.4 1.0 CB B:VAL370 4.1 95.1 1.0 CG2 B:VAL370 4.1 95.1 1.0 NE2 B:HIS355 4.1 118.5 1.0 CA B:VAL370 4.6 91.4 1.0 CA B:HIS355 4.7 123.3 1.0 O B:CYS368 4.7 119.8 1.0 N B:CYS368 4.7 103.4 1.0 CA B:ASP369 4.8 93.9 1.0 C B:ASP369 4.8 99.0 1.0 N B:HIS355 4.8 115.5 1.0 N B:TYR371 5.0 93.0 1.0

H.J.Choi, D.U.Ki, S.I.Yoon. Structural and Biochemical Analysis of Penicillin-Binding Protein 2 From Campylobacter Jejuni. Biochem.Biophys.Res.Commun. V. 710 49859 2024.
ISSN: ESSN 1090-2104
PubMed: 38581948
DOI: 10.1016/J.BBRC.2024.149859