Zinc in PDB 8olk: Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_13

All present enzymatic activity of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_13:
4.2.1.1;

The structure of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_13, PDB code: 8olk was solved by J.Brynda, P.M.Rezacova, E.Kudova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.58 / 1.27
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.15, 41.34, 72.14, 90, 104.29, 90
R / Rfree (%)	13.6 / 16.9

The binding sites of Zinc atom in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_13 (pdb code 8olk). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_13, PDB code: 8olk:

Zinc binding site 1 out of 1 in the Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_13


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Carbonic Anhydrase 2 in Complex with STERIOD_SULPHAMOYL AKI_13 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn301 b:9.4 occ:1.00 N19 A:VQH302 2.0 6.0 0.6 NE2 A:HIS94 2.0 9.5 1.0 NE2 A:HIS96 2.0 9.4 1.0 ND1 A:HIS119 2.0 8.2 1.0 CE1 A:HIS119 2.9 8.5 1.0 CD2 A:HIS94 3.0 9.8 1.0 CD2 A:HIS96 3.0 9.3 1.0 CE1 A:HIS96 3.0 9.9 1.0 CE1 A:HIS94 3.0 9.7 1.0 S22 A:VQH302 3.1 7.8 0.6 CG A:HIS119 3.1 8.4 1.0 O20 A:VQH302 3.3 9.2 0.6 CB A:HIS119 3.5 8.9 1.0 O25 A:VQH302 3.6 8.5 0.6 O A:HOH625 3.7 17.2 1.0 OG1 A:THR198 3.9 9.4 1.0 OE1 A:GLU106 4.0 9.5 1.0 NE2 A:HIS119 4.1 8.8 1.0 ND1 A:HIS96 4.1 10.3 1.0 CG A:HIS94 4.1 10.3 1.0 ND1 A:HIS94 4.1 10.2 1.0 CG A:HIS96 4.2 9.6 1.0 CD2 A:HIS119 4.2 8.9 1.0 O A:HOH611 4.3 25.4 1.0 O21 A:VQH302 4.3 8.4 0.6 CD A:GLU106 4.9 9.7 1.0 CA A:HIS119 5.0 8.7 1.0

J.Brynda, P.M.Rezacova, E.Kudova. Carbonic Anhydrase in Complex with STERIOD_SULPHAMOYL To Be Published.