Zinc in PDB 9fgo: Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site

The structure of Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site, PDB code: 9fgo was solved by X.Ni, L.Koekemoer, E.P.Williams, S.Wang, N.D.Wright, A.S.Godoy, J.C.Aschenbrenner, B.H.Balcomb, R.M.Lithgo, P.G.Marples, M.Fairhead, W.Thompson, K.Kirkegaard, D.Fearon, M.A.Walsh, F.Von Delft, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.69 / 1.43
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	61.544, 61.544, 78.932, 90, 90, 120
R / Rfree (%)	15.1 / 16.5

The structure of Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Zinc atom in the Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site (pdb code 9fgo). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site, PDB code: 9fgo:

Zinc binding site 1 out of 1 in the Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:19.1 occ:1.00 ND1 A:HIS118 2.1 17.9 1.0 SG A:CYS116 2.3 17.5 1.0 SG A:CYS58 2.3 20.2 1.0 SG A:CYS56 2.3 18.7 1.0 CE1 A:HIS118 3.0 21.1 1.0 CG A:HIS118 3.1 20.6 1.0 CB A:CYS58 3.1 17.2 1.0 CB A:CYS56 3.2 19.4 1.0 CB A:CYS116 3.3 18.1 1.0 CB A:HIS118 3.5 19.4 1.0 O A:HOH400 3.8 26.6 1.0 N A:HIS118 3.9 18.7 1.0 NE2 A:HIS118 4.1 24.9 1.0 CD2 A:HIS118 4.2 23.9 1.0 N A:CYS58 4.2 18.3 1.0 CA A:CYS58 4.2 18.1 1.0 CA A:HIS118 4.3 18.9 1.0 N A:GLN117 4.4 19.5 1.0 CB A:ALA54 4.6 16.6 1.0 CA A:CYS56 4.6 20.4 1.0 CA A:CYS116 4.6 17.0 1.0 C A:CYS116 4.7 17.9 1.0 O A:HOH428 4.8 34.1 1.0 C A:GLN117 4.9 19.2 1.0

X.Ni, L.Koekemoer, E.P.Williams, S.Wang, N.D.Wright, A.S.Godoy, J.C.Aschenbrenner, B.H.Balcomb, R.M.Lithgo, P.G.Marples, M.Fairhead, W.Thompson, K.Kirkegaard, D.Fearon, M.A.Walsh, F.Von Delft. Crystal Structure of Enterovirus 71 2A Protease Mutant C110A Containing VP1-2A Junction in the Active Site To Be Published.