Zinc in PDB 9c8v: Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)

All present enzymatic activity of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm):
2.7.7.102; 2.7.7.7;

The structure of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) also contains other interesting chemical elements:

Iron

(Fe)

4 atoms

The binding sites of Zinc atom in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) (pdb code 9c8v). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm), PDB code: 9c8v:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn501 b:84.2 occ:1.00 SG A:CYS128 2.3 36.6 1.0 SG A:CYS121 2.3 52.5 1.0 SG A:CYS131 2.3 55.2 1.0 SG A:CYS122 2.3 51.1 1.0 CB A:CYS131 3.1 41.2 1.0 CB A:CYS128 3.1 34.3 1.0 N A:CYS128 3.4 34.0 1.0 CB A:CYS122 3.6 39.4 1.0 CB A:CYS121 3.6 41.2 1.0 CA A:CYS128 3.7 32.7 1.0 NH1 A:ARG119 3.8 39.2 1.0 N A:CYS131 3.9 35.4 1.0 N A:CYS122 3.9 35.8 1.0 O A:CYS128 4.0 34.4 1.0 CA A:CYS131 4.1 37.0 1.0 C A:ILE127 4.2 36.3 1.0 C A:CYS128 4.2 34.8 1.0 C A:CYS121 4.2 38.4 1.0 CA A:CYS122 4.3 37.7 1.0 CA A:CYS121 4.5 42.8 1.0 CA A:ILE127 4.5 35.6 1.0 C A:LYS130 4.7 37.5 1.0 CD A:ARG119 4.7 32.6 1.0 O A:CYS121 4.9 35.0 1.0 CG A:ARG119 4.9 35.4 1.0 N A:LYS130 4.9 35.7 1.0 O A:ILE127 4.9 36.4 1.0 CZ A:ARG119 4.9 41.8 1.0 CB A:LYS130 5.0 41.1 1.0

Zinc binding site 2 out of 3 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1501 b:79.3 occ:1.00 SG C:CYS1315 2.3 45.3 1.0 SG C:CYS1286 2.3 26.9 1.0 SG C:CYS1283 2.3 34.3 1.0 SG C:CYS1310 2.3 43.5 1.0 CB C:CYS1315 2.9 36.4 1.0 CB C:CYS1283 3.1 22.9 1.0 CB C:CYS1286 3.4 23.1 1.0 CB C:CYS1310 3.4 35.6 1.0 N C:CYS1286 4.3 31.3 1.0 CA C:CYS1315 4.4 35.0 1.0 CA C:CYS1286 4.4 25.8 1.0 CG2 C:THR1285 4.4 21.4 1.0 CB C:ASN1312 4.4 30.6 1.0 CA C:CYS1283 4.6 19.8 1.0 CA C:CYS1310 4.8 31.1 1.0

Zinc binding site 3 out of 3 in the Human Dna Polymerase Alpha/Primase - Chapso (4 Mm)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1502 b:29.0 occ:1.00 SG C:CYS1353 2.3 5.9 1.0 SG C:CYS1348 2.3 8.9 1.0 SG C:CYS1371 2.3 4.2 1.0 CB C:CYS1348 3.0 2.9 1.0 CB C:CYS1353 3.2 7.4 1.0 CB C:CYS1371 3.2 2.0 1.0 CB C:CYS1374 3.4 7.7 1.0 CB C:ALA1377 3.9 5.5 1.0 N C:CYS1374 3.9 5.5 1.0 CB C:ASN1355 4.0 3.2 1.0 O C:CYS1374 4.2 12.3 1.0 CA C:CYS1374 4.2 6.3 1.0 SG C:CYS1374 4.3 13.8 1.0 CA C:CYS1348 4.4 1.7 1.0 N C:ASN1355 4.5 2.6 1.0 CA C:CYS1353 4.6 9.3 1.0 CA C:CYS1371 4.7 1.5 1.0 C C:CYS1374 4.7 7.2 1.0 N C:ARG1354 4.7 6.0 1.0 C C:CYS1353 4.8 7.3 1.0 CA C:ASN1355 4.9 1.8 1.0 CB C:GLU1350 5.0 7.7 1.0

K.M.Abe, G.Li, Q.He, T.Grant, C.Lim. Human Dna Polymerase Alpha/Primase - Chapso (4 Mm) To Be Published.