Zinc in PDB 8zpv: Nipah Virus Polymerase Complex

All present enzymatic activity of Nipah Virus Polymerase Complex:
2.1.1.375; 2.7.7.48; 2.7.7.88;

The binding sites of Zinc atom in the Nipah Virus Polymerase Complex (pdb code 8zpv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Nipah Virus Polymerase Complex, PDB code: 8zpv:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Nipah Virus Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Nipah Virus Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2301 b:230.9 occ:1.00 OE1 A:GLU1223 2.1 160.1 1.0 SG A:CYS1429 2.4 198.1 1.0 SG A:CYS1428 2.4 194.8 1.0 SG A:CYS1191 2.4 160.5 1.0 CB A:CYS1428 2.6 194.8 1.0 C A:CYS1428 2.9 194.8 1.0 N A:CYS1429 2.9 198.1 1.0 CB A:CYS1429 3.0 198.1 1.0 CA A:CYS1428 3.2 194.8 1.0 CD A:GLU1223 3.3 160.1 1.0 CB A:CYS1191 3.4 160.5 1.0 O A:CYS1428 3.4 194.8 1.0 CA A:CYS1429 3.5 198.1 1.0 CG A:GLU1223 4.2 160.1 1.0 OE2 A:GLU1223 4.2 160.1 1.0 CA A:CYS1191 4.4 160.5 1.0 N A:CYS1428 4.5 194.8 1.0 OG A:SER1192 4.6 150.4 1.0 N A:SER1192 4.7 150.4 1.0 C A:CYS1429 4.8 198.1 1.0 CB A:GLU1223 4.9 160.1 1.0 C A:CYS1191 5.0 160.5 1.0

Zinc binding site 2 out of 2 in the Nipah Virus Polymerase Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Nipah Virus Polymerase Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn2302 b:200.1 occ:1.00 NE2 A:HIS1423 2.1 158.5 1.0 NE2 A:HIS1421 2.1 149.6 1.0 CB A:CYS1236 2.3 174.2 1.0 SG A:CYS1239 2.4 174.8 1.0 SG A:CYS1236 2.4 174.2 1.0 CE1 A:HIS1423 2.8 158.5 1.0 CE1 A:HIS1421 2.9 149.6 1.0 CA A:CYS1239 3.1 174.8 1.0 CD2 A:HIS1421 3.1 149.6 1.0 CB A:CYS1239 3.2 174.8 1.0 CD2 A:HIS1423 3.4 158.5 1.0 OE2 A:GLU1240 3.5 175.5 1.0 CA A:CYS1236 3.8 174.2 1.0 ND1 A:HIS1421 4.0 149.6 1.0 C A:CYS1239 4.0 174.8 1.0 ND1 A:HIS1423 4.0 158.5 1.0 N A:CYS1239 4.1 174.8 1.0 CG A:HIS1421 4.1 149.6 1.0 O A:CYS1236 4.2 174.2 1.0 O A:CYS1239 4.3 174.8 1.0 CG A:HIS1423 4.3 158.5 1.0 C A:CYS1236 4.5 174.2 1.0 N A:CYS1236 4.6 174.2 1.0 CD A:GLU1240 4.7 175.5 1.0 N A:GLU1240 4.9 175.5 1.0

Y.R.Wang, H.Q.Zhang. Structure of Polymerase Complex Sci Adv 2024.
ISSN: ESSN 2375-2548