Zinc in PDB 8yxp: Structure of Mumps Virus L Protein (STATE2)

All present enzymatic activity of Structure of Mumps Virus L Protein (STATE2):
2.7.7.48; 2.7.7.88;

The binding sites of Zinc atom in the Structure of Mumps Virus L Protein (STATE2) (pdb code 8yxp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Mumps Virus L Protein (STATE2), PDB code: 8yxp:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Structure of Mumps Virus L Protein (STATE2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Mumps Virus L Protein (STATE2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn3001 b:128.1 occ:1.00 ND1 A:HIS1372 2.0 93.4 1.0 NE2 A:HIS1374 2.0 92.5 1.0 CE1 A:HIS1374 2.2 91.5 1.0 SG A:CYS1190 2.3 110.6 1.0 SG A:CYS1187 2.3 113.8 1.0 CE1 A:HIS1372 2.6 94.2 1.0 CB A:CYS1187 2.8 107.3 1.0 CG A:HIS1372 2.9 92.4 1.0 CB A:CYS1190 3.1 109.3 1.0 CD2 A:HIS1374 3.4 90.4 1.0 NE2 A:HIS1372 3.5 94.1 1.0 ND1 A:HIS1374 3.5 88.8 1.0 CB A:HIS1372 3.6 92.1 1.0 CD2 A:HIS1372 3.7 92.9 1.0 N A:CYS1190 3.8 109.3 1.0 CA A:CYS1190 3.9 109.5 1.0 CD2 A:PHE1197 4.0 94.1 1.0 CG A:HIS1374 4.1 86.8 1.0 CA A:CYS1187 4.3 106.9 1.0 CE2 A:PHE1197 4.5 96.3 1.0 CG A:PHE1197 4.7 94.6 1.0 CB A:PHE1197 4.9 93.3 1.0 C A:CYS1187 4.9 109.0 1.0 C A:HIS1189 4.9 103.5 1.0 O A:CYS1187 5.0 110.0 1.0

Zinc binding site 2 out of 2 in the Structure of Mumps Virus L Protein (STATE2)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Mumps Virus L Protein (STATE2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn3002 b:156.9 occ:1.00 SG A:CYS1142 2.3 76.2 1.0 SG A:CYS1380 2.3 96.1 1.0 SG A:CYS1379 2.3 105.4 1.0 N A:CYS1380 3.4 91.3 1.0 CB A:CYS1379 3.5 95.8 1.0 CB A:CYS1142 3.7 65.6 1.0 CB A:CYS1380 3.7 90.9 1.0 C A:CYS1379 3.8 94.8 1.0 N A:CYS1379 3.9 97.2 1.0 OE2 A:GLU1174 3.9 63.0 1.0 CA A:CYS1380 3.9 92.1 1.0 CA A:CYS1379 3.9 95.6 1.0 CG A:GLU1174 4.1 63.5 1.0 CA A:CYS1142 4.2 61.1 1.0 CD A:GLU1174 4.5 64.2 1.0 N A:SER1143 4.6 57.6 1.0 O A:CYS1379 4.7 94.7 1.0 OG A:SER1143 4.9 58.5 1.0 C A:CYS1142 4.9 67.4 1.0 O A:GLU1174 5.0 55.5 1.0 C A:SER1378 5.0 100.0 1.0

T.Li, M.Liu, Z.Gu, X.Su, Y.Liu, J.Lin, Y.Zhang, Q.T.Shen. Structures of the Mumps Virus Polymerase Complex Via Cryo-Electron Microscopy. Nat Commun V. 15 4189 2024.
ISSN: ESSN 2041-1723
PubMed: 38760379
DOI: 10.1038/S41467-024-48389-9