Zinc in PDB 8yxm: Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus

Enzymatic activity of Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus

All present enzymatic activity of Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus:
2.7.7.48; 2.7.7.88;

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus (pdb code 8yxm). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus, PDB code: 8yxm:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8yxm

Go back to Zinc Binding Sites List in 8yxm
Zinc binding site 1 out of 2 in the Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn3001

b:145.3
occ:1.00
NE2 A:HIS1374 1.7 45.4 1.0
ND1 A:HIS1372 2.0 41.6 1.0
SG A:CYS1187 2.1 62.0 1.0
CE1 A:HIS1374 2.5 45.4 1.0
SG A:CYS1190 2.9 63.6 1.0
CD2 A:HIS1374 2.9 45.4 1.0
CE1 A:HIS1372 2.9 41.6 1.0
CG A:HIS1372 3.0 41.6 1.0
CB A:CYS1187 3.2 62.0 1.0
CB A:CYS1190 3.2 63.6 1.0
CB A:HIS1372 3.3 41.6 1.0
N A:CYS1190 3.5 63.6 1.0
ND1 A:HIS1374 3.7 45.4 1.0
CA A:CYS1190 3.9 63.6 1.0
CG A:HIS1374 3.9 45.4 1.0
NE2 A:HIS1372 4.1 41.6 1.0
CD2 A:HIS1372 4.1 41.6 1.0
C A:HIS1189 4.5 57.4 1.0
CB A:HIS1189 4.5 57.4 1.0
CA A:CYS1187 4.6 62.0 1.0
CD1 A:PHE1197 4.6 45.3 1.0
CG A:PHE1197 4.7 45.3 1.0
CA A:HIS1372 4.8 41.6 1.0
CA A:HIS1189 4.8 57.4 1.0
N A:HIS1189 4.8 57.4 1.0
C A:CYS1187 4.9 62.0 1.0
CB A:PHE1197 5.0 45.3 1.0
CE1 A:PHE1197 5.0 45.3 1.0

Zinc binding site 2 out of 2 in 8yxm

Go back to Zinc Binding Sites List in 8yxm
Zinc binding site 2 out of 2 in the Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of N-Terminal Domain of L Protein Bound with Phosphoprotein From Mumps Virus within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn3002

b:149.6
occ:1.00
SG A:CYS1142 1.9 49.7 1.0
SG A:CYS1379 2.3 69.4 1.0
SG A:CYS1380 2.3 66.6 1.0
OE2 A:GLU1174 2.7 46.0 1.0
N A:CYS1380 2.9 66.6 1.0
CB A:CYS1142 3.0 49.7 1.0
CB A:CYS1380 3.3 66.6 1.0
CA A:CYS1380 3.4 66.6 1.0
CB A:CYS1379 3.4 69.4 1.0
C A:CYS1379 3.6 69.4 1.0
CD A:GLU1174 3.7 46.0 1.0
CA A:CYS1142 3.8 49.7 1.0
CA A:CYS1379 3.9 69.4 1.0
N A:CYS1379 4.2 69.4 1.0
CG A:GLU1174 4.4 46.0 1.0
O A:CYS1379 4.5 69.4 1.0
NH2 A:ARG1382 4.5 64.7 1.0
N A:SER1143 4.5 41.8 1.0
OE1 A:GLU1174 4.6 46.0 1.0
C A:CYS1142 4.6 49.7 1.0
C A:CYS1380 4.9 66.6 1.0
N A:CYS1142 5.0 49.7 1.0

Reference:

T.Li, M.Liu, Z.Gu, X.Su, Y.Liu, J.Lin, Y.Zhang, Q.T.Shen. Structures of the Mumps Virus Polymerase Complex Via Cryo-Electron Microscopy. Nat Commun V. 15 4189 2024.
ISSN: ESSN 2041-1723
PubMed: 38760379
DOI: 10.1038/S41467-024-48389-9
Page generated: Thu Oct 31 14:07:50 2024

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