Zinc in PDB 8yx6: Structure of A Cys-Loop Receptor in Zinc Binding State

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of A Cys-Loop Receptor in Zinc Binding State (pdb code 8yx6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 10 binding sites of Zinc where determined in the Structure of A Cys-Loop Receptor in Zinc Binding State, PDB code: 8yx6:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Zinc binding site 1 out of 10 in 8yx6

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Zinc binding site 1 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn502

b:121.3
occ:1.00
ND1 A:HIS163 2.3 86.3 1.0
NE2 A:HIS168 2.3 93.6 1.0
CD2 A:HIS168 2.9 93.6 1.0
CG A:HIS163 3.3 86.3 1.0
CE1 A:HIS163 3.3 86.3 1.0
CE1 A:HIS168 3.4 93.6 1.0
CB A:HIS163 3.5 86.3 1.0
O A:ARG166 4.0 85.1 1.0
CG A:HIS168 4.1 93.6 1.0
ND1 A:HIS168 4.3 93.6 1.0
NE2 A:HIS163 4.4 86.3 1.0
CD2 A:HIS163 4.4 86.3 1.0

Zinc binding site 2 out of 10 in 8yx6

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Zinc binding site 2 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn503

b:126.0
occ:1.00
OD1 A:ASP142 2.0 98.2 1.0
OD1 A:ASP140 2.0 96.4 1.0
OD2 A:ASP142 2.0 98.2 1.0
OD2 A:ASP140 2.0 96.4 1.0
CG A:ASP140 2.1 96.4 1.0
CG A:ASP142 2.2 98.2 1.0
ND1 A:HIS144 2.3 89.5 1.0
CG A:HIS144 2.9 89.5 1.0
CB A:HIS144 3.0 89.5 1.0
CE1 A:HIS144 3.4 89.5 1.0
CB A:ASP140 3.5 96.4 1.0
CB A:ASP142 3.7 98.2 1.0
N A:HIS144 3.8 89.5 1.0
CA A:HIS144 4.0 89.5 1.0
CD2 A:HIS144 4.1 89.5 1.0
NE2 A:HIS144 4.3 89.5 1.0
N A:ASP142 4.4 98.2 1.0
CA A:ASP142 4.4 98.2 1.0
O A:HIS144 4.5 89.5 1.0
C A:ASP142 4.6 98.2 1.0
CA A:ASP140 4.6 96.4 1.0
N A:GLY143 4.7 88.6 1.0
C A:HIS144 4.7 89.5 1.0
N A:ASP140 4.9 96.4 1.0
C A:ASP140 4.9 96.4 1.0

Zinc binding site 3 out of 10 in 8yx6

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Zinc binding site 3 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn502

b:114.1
occ:1.00
ND1 B:HIS163 2.3 84.8 1.0
NE2 B:HIS168 2.3 92.6 1.0
CD2 B:HIS168 2.9 92.6 1.0
CG B:HIS163 3.3 84.8 1.0
CE1 B:HIS163 3.3 84.8 1.0
CE1 B:HIS168 3.4 92.6 1.0
CB B:HIS163 3.5 84.8 1.0
O B:ARG166 4.0 85.0 1.0
CG B:HIS168 4.1 92.6 1.0
ND1 B:HIS168 4.3 92.6 1.0
NE2 B:HIS163 4.4 84.8 1.0
CD2 B:HIS163 4.4 84.8 1.0

Zinc binding site 4 out of 10 in 8yx6

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Zinc binding site 4 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Zn503

b:124.3
occ:1.00
OD1 B:ASP142 2.0 97.1 1.0
OD1 B:ASP140 2.0 96.7 1.0
OD2 B:ASP142 2.0 97.1 1.0
OD2 B:ASP140 2.0 96.7 1.0
CG B:ASP140 2.1 96.7 1.0
CG B:ASP142 2.2 97.1 1.0
ND1 B:HIS144 2.3 89.6 1.0
CG B:HIS144 2.9 89.6 1.0
CB B:HIS144 3.0 89.6 1.0
CE1 B:HIS144 3.4 89.6 1.0
CB B:ASP140 3.5 96.7 1.0
CB B:ASP142 3.7 97.1 1.0
N B:HIS144 3.8 89.6 1.0
CA B:HIS144 4.0 89.6 1.0
CD2 B:HIS144 4.1 89.6 1.0
NE2 B:HIS144 4.3 89.6 1.0
N B:ASP142 4.4 97.1 1.0
CA B:ASP142 4.4 97.1 1.0
O B:HIS144 4.5 89.6 1.0
C B:ASP142 4.6 97.1 1.0
CA B:ASP140 4.6 96.7 1.0
N B:GLY143 4.7 88.4 1.0
C B:HIS144 4.7 89.6 1.0
N B:ASP140 4.9 96.7 1.0
C B:ASP140 4.9 96.7 1.0

Zinc binding site 5 out of 10 in 8yx6

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Zinc binding site 5 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn502

b:126.5
occ:1.00
ND1 C:HIS163 2.3 86.7 1.0
NE2 C:HIS168 2.3 93.3 1.0
CD2 C:HIS168 2.9 93.3 1.0
CG C:HIS163 3.3 86.7 1.0
CE1 C:HIS163 3.3 86.7 1.0
CE1 C:HIS168 3.4 93.3 1.0
CB C:HIS163 3.5 86.7 1.0
O C:ARG166 4.0 86.6 1.0
CG C:HIS168 4.1 93.3 1.0
ND1 C:HIS168 4.3 93.3 1.0
NE2 C:HIS163 4.4 86.7 1.0
CD2 C:HIS163 4.4 86.7 1.0

Zinc binding site 6 out of 10 in 8yx6

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Zinc binding site 6 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Zn503

b:128.1
occ:1.00
OD1 C:ASP142 2.0 100.2 1.0
OD1 C:ASP140 2.0 98.8 1.0
OD2 C:ASP140 2.0 98.8 1.0
OD2 C:ASP142 2.0 100.2 1.0
CG C:ASP140 2.1 98.8 1.0
CG C:ASP142 2.2 100.2 1.0
ND1 C:HIS144 2.3 90.9 1.0
CG C:HIS144 2.9 90.9 1.0
CB C:HIS144 3.0 90.9 1.0
CE1 C:HIS144 3.4 90.9 1.0
CB C:ASP140 3.5 98.8 1.0
CB C:ASP142 3.7 100.2 1.0
N C:HIS144 3.8 90.9 1.0
CA C:HIS144 4.0 90.9 1.0
CD2 C:HIS144 4.1 90.9 1.0
NE2 C:HIS144 4.3 90.9 1.0
N C:ASP142 4.4 100.2 1.0
CA C:ASP142 4.4 100.2 1.0
O C:HIS144 4.5 90.9 1.0
C C:ASP142 4.6 100.2 1.0
CA C:ASP140 4.6 98.8 1.0
N C:GLY143 4.7 90.7 1.0
C C:HIS144 4.8 90.9 1.0
N C:ASP140 4.9 98.8 1.0
C C:ASP140 4.9 98.8 1.0

Zinc binding site 7 out of 10 in 8yx6

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Zinc binding site 7 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 7 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn502

b:127.8
occ:1.00
ND1 D:HIS163 2.3 86.4 1.0
NE2 D:HIS168 2.3 93.8 1.0
CD2 D:HIS168 2.9 93.8 1.0
CG D:HIS163 3.3 86.4 1.0
CE1 D:HIS163 3.3 86.4 1.0
CE1 D:HIS168 3.4 93.8 1.0
CB D:HIS163 3.5 86.4 1.0
O D:ARG166 4.0 86.0 1.0
CG D:HIS168 4.1 93.8 1.0
ND1 D:HIS168 4.3 93.8 1.0
NE2 D:HIS163 4.4 86.4 1.0
CD2 D:HIS163 4.4 86.4 1.0

Zinc binding site 8 out of 10 in 8yx6

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Zinc binding site 8 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 8 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Zn503

b:127.3
occ:1.00
OD1 D:ASP142 2.0 96.8 1.0
OD1 D:ASP140 2.0 96.1 1.0
OD2 D:ASP142 2.0 96.8 1.0
OD2 D:ASP140 2.0 96.1 1.0
CG D:ASP140 2.1 96.1 1.0
CG D:ASP142 2.2 96.8 1.0
ND1 D:HIS144 2.3 88.5 1.0
CG D:HIS144 2.9 88.5 1.0
CB D:HIS144 3.0 88.5 1.0
CE1 D:HIS144 3.4 88.5 1.0
CB D:ASP140 3.5 96.1 1.0
CB D:ASP142 3.7 96.8 1.0
N D:HIS144 3.8 88.5 1.0
CA D:HIS144 4.0 88.5 1.0
CD2 D:HIS144 4.1 88.5 1.0
NE2 D:HIS144 4.3 88.5 1.0
N D:ASP142 4.4 96.8 1.0
CA D:ASP142 4.4 96.8 1.0
O D:HIS144 4.5 88.5 1.0
C D:ASP142 4.6 96.8 1.0
CA D:ASP140 4.6 96.1 1.0
N D:GLY143 4.7 87.6 1.0
C D:HIS144 4.8 88.5 1.0
N D:ASP140 4.9 96.1 1.0
C D:ASP140 4.9 96.1 1.0

Zinc binding site 9 out of 10 in 8yx6

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Zinc binding site 9 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 9 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn502

b:129.9
occ:1.00
ND1 E:HIS163 2.3 88.2 1.0
NE2 E:HIS168 2.3 92.5 1.0
CD2 E:HIS168 2.9 92.5 1.0
CG E:HIS163 3.3 88.2 1.0
CE1 E:HIS163 3.3 88.2 1.0
CE1 E:HIS168 3.4 92.5 1.0
CB E:HIS163 3.5 88.2 1.0
O E:ARG166 4.0 86.2 1.0
CG E:HIS168 4.1 92.5 1.0
ND1 E:HIS168 4.3 92.5 1.0
NE2 E:HIS163 4.4 88.2 1.0
CD2 E:HIS163 4.4 88.2 1.0

Zinc binding site 10 out of 10 in 8yx6

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Zinc binding site 10 out of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 10 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Zn503

b:126.2
occ:1.00
OD1 E:ASP142 2.0 96.8 1.0
OD1 E:ASP140 2.0 96.2 1.0
OD2 E:ASP142 2.0 96.8 1.0
OD2 E:ASP140 2.0 96.2 1.0
CG E:ASP140 2.1 96.2 1.0
CG E:ASP142 2.2 96.8 1.0
ND1 E:HIS144 2.3 88.6 1.0
CG E:HIS144 2.9 88.6 1.0
CB E:HIS144 3.0 88.6 1.0
CE1 E:HIS144 3.4 88.6 1.0
CB E:ASP140 3.5 96.2 1.0
CB E:ASP142 3.7 96.8 1.0
N E:HIS144 3.8 88.6 1.0
CA E:HIS144 4.0 88.6 1.0
CD2 E:HIS144 4.1 88.6 1.0
NE2 E:HIS144 4.3 88.6 1.0
N E:ASP142 4.4 96.8 1.0
CA E:ASP142 4.4 96.8 1.0
O E:HIS144 4.5 88.6 1.0
C E:ASP142 4.6 96.8 1.0
CA E:ASP140 4.6 96.2 1.0
N E:GLY143 4.7 87.5 1.0
C E:HIS144 4.8 88.6 1.0
N E:ASP140 4.9 96.2 1.0
C E:ASP140 4.9 96.2 1.0

Reference:

X.H.Lu, X.Yang, Y.Q.Shen. Structure of A Cys-Loop Receptor in Zinc Binding State To Be Published.
Page generated: Sun Feb 9 00:56:48 2025

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