Zinc in PDB 8yx6: Structure of A Cys-Loop Receptor in Zinc Binding State
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of A Cys-Loop Receptor in Zinc Binding State
(pdb code 8yx6). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 10 binding sites of Zinc where determined in the
Structure of A Cys-Loop Receptor in Zinc Binding State, PDB code: 8yx6:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Zinc binding site 1 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 1 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn502
b:121.3
occ:1.00
|
ND1
|
A:HIS163
|
2.3
|
86.3
|
1.0
|
NE2
|
A:HIS168
|
2.3
|
93.6
|
1.0
|
CD2
|
A:HIS168
|
2.9
|
93.6
|
1.0
|
CG
|
A:HIS163
|
3.3
|
86.3
|
1.0
|
CE1
|
A:HIS163
|
3.3
|
86.3
|
1.0
|
CE1
|
A:HIS168
|
3.4
|
93.6
|
1.0
|
CB
|
A:HIS163
|
3.5
|
86.3
|
1.0
|
O
|
A:ARG166
|
4.0
|
85.1
|
1.0
|
CG
|
A:HIS168
|
4.1
|
93.6
|
1.0
|
ND1
|
A:HIS168
|
4.3
|
93.6
|
1.0
|
NE2
|
A:HIS163
|
4.4
|
86.3
|
1.0
|
CD2
|
A:HIS163
|
4.4
|
86.3
|
1.0
|
|
Zinc binding site 2 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 2 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn503
b:126.0
occ:1.00
|
OD1
|
A:ASP142
|
2.0
|
98.2
|
1.0
|
OD1
|
A:ASP140
|
2.0
|
96.4
|
1.0
|
OD2
|
A:ASP142
|
2.0
|
98.2
|
1.0
|
OD2
|
A:ASP140
|
2.0
|
96.4
|
1.0
|
CG
|
A:ASP140
|
2.1
|
96.4
|
1.0
|
CG
|
A:ASP142
|
2.2
|
98.2
|
1.0
|
ND1
|
A:HIS144
|
2.3
|
89.5
|
1.0
|
CG
|
A:HIS144
|
2.9
|
89.5
|
1.0
|
CB
|
A:HIS144
|
3.0
|
89.5
|
1.0
|
CE1
|
A:HIS144
|
3.4
|
89.5
|
1.0
|
CB
|
A:ASP140
|
3.5
|
96.4
|
1.0
|
CB
|
A:ASP142
|
3.7
|
98.2
|
1.0
|
N
|
A:HIS144
|
3.8
|
89.5
|
1.0
|
CA
|
A:HIS144
|
4.0
|
89.5
|
1.0
|
CD2
|
A:HIS144
|
4.1
|
89.5
|
1.0
|
NE2
|
A:HIS144
|
4.3
|
89.5
|
1.0
|
N
|
A:ASP142
|
4.4
|
98.2
|
1.0
|
CA
|
A:ASP142
|
4.4
|
98.2
|
1.0
|
O
|
A:HIS144
|
4.5
|
89.5
|
1.0
|
C
|
A:ASP142
|
4.6
|
98.2
|
1.0
|
CA
|
A:ASP140
|
4.6
|
96.4
|
1.0
|
N
|
A:GLY143
|
4.7
|
88.6
|
1.0
|
C
|
A:HIS144
|
4.7
|
89.5
|
1.0
|
N
|
A:ASP140
|
4.9
|
96.4
|
1.0
|
C
|
A:ASP140
|
4.9
|
96.4
|
1.0
|
|
Zinc binding site 3 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 3 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn502
b:114.1
occ:1.00
|
ND1
|
B:HIS163
|
2.3
|
84.8
|
1.0
|
NE2
|
B:HIS168
|
2.3
|
92.6
|
1.0
|
CD2
|
B:HIS168
|
2.9
|
92.6
|
1.0
|
CG
|
B:HIS163
|
3.3
|
84.8
|
1.0
|
CE1
|
B:HIS163
|
3.3
|
84.8
|
1.0
|
CE1
|
B:HIS168
|
3.4
|
92.6
|
1.0
|
CB
|
B:HIS163
|
3.5
|
84.8
|
1.0
|
O
|
B:ARG166
|
4.0
|
85.0
|
1.0
|
CG
|
B:HIS168
|
4.1
|
92.6
|
1.0
|
ND1
|
B:HIS168
|
4.3
|
92.6
|
1.0
|
NE2
|
B:HIS163
|
4.4
|
84.8
|
1.0
|
CD2
|
B:HIS163
|
4.4
|
84.8
|
1.0
|
|
Zinc binding site 4 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 4 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn503
b:124.3
occ:1.00
|
OD1
|
B:ASP142
|
2.0
|
97.1
|
1.0
|
OD1
|
B:ASP140
|
2.0
|
96.7
|
1.0
|
OD2
|
B:ASP142
|
2.0
|
97.1
|
1.0
|
OD2
|
B:ASP140
|
2.0
|
96.7
|
1.0
|
CG
|
B:ASP140
|
2.1
|
96.7
|
1.0
|
CG
|
B:ASP142
|
2.2
|
97.1
|
1.0
|
ND1
|
B:HIS144
|
2.3
|
89.6
|
1.0
|
CG
|
B:HIS144
|
2.9
|
89.6
|
1.0
|
CB
|
B:HIS144
|
3.0
|
89.6
|
1.0
|
CE1
|
B:HIS144
|
3.4
|
89.6
|
1.0
|
CB
|
B:ASP140
|
3.5
|
96.7
|
1.0
|
CB
|
B:ASP142
|
3.7
|
97.1
|
1.0
|
N
|
B:HIS144
|
3.8
|
89.6
|
1.0
|
CA
|
B:HIS144
|
4.0
|
89.6
|
1.0
|
CD2
|
B:HIS144
|
4.1
|
89.6
|
1.0
|
NE2
|
B:HIS144
|
4.3
|
89.6
|
1.0
|
N
|
B:ASP142
|
4.4
|
97.1
|
1.0
|
CA
|
B:ASP142
|
4.4
|
97.1
|
1.0
|
O
|
B:HIS144
|
4.5
|
89.6
|
1.0
|
C
|
B:ASP142
|
4.6
|
97.1
|
1.0
|
CA
|
B:ASP140
|
4.6
|
96.7
|
1.0
|
N
|
B:GLY143
|
4.7
|
88.4
|
1.0
|
C
|
B:HIS144
|
4.7
|
89.6
|
1.0
|
N
|
B:ASP140
|
4.9
|
96.7
|
1.0
|
C
|
B:ASP140
|
4.9
|
96.7
|
1.0
|
|
Zinc binding site 5 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 5 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn502
b:126.5
occ:1.00
|
ND1
|
C:HIS163
|
2.3
|
86.7
|
1.0
|
NE2
|
C:HIS168
|
2.3
|
93.3
|
1.0
|
CD2
|
C:HIS168
|
2.9
|
93.3
|
1.0
|
CG
|
C:HIS163
|
3.3
|
86.7
|
1.0
|
CE1
|
C:HIS163
|
3.3
|
86.7
|
1.0
|
CE1
|
C:HIS168
|
3.4
|
93.3
|
1.0
|
CB
|
C:HIS163
|
3.5
|
86.7
|
1.0
|
O
|
C:ARG166
|
4.0
|
86.6
|
1.0
|
CG
|
C:HIS168
|
4.1
|
93.3
|
1.0
|
ND1
|
C:HIS168
|
4.3
|
93.3
|
1.0
|
NE2
|
C:HIS163
|
4.4
|
86.7
|
1.0
|
CD2
|
C:HIS163
|
4.4
|
86.7
|
1.0
|
|
Zinc binding site 6 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 6 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn503
b:128.1
occ:1.00
|
OD1
|
C:ASP142
|
2.0
|
100.2
|
1.0
|
OD1
|
C:ASP140
|
2.0
|
98.8
|
1.0
|
OD2
|
C:ASP140
|
2.0
|
98.8
|
1.0
|
OD2
|
C:ASP142
|
2.0
|
100.2
|
1.0
|
CG
|
C:ASP140
|
2.1
|
98.8
|
1.0
|
CG
|
C:ASP142
|
2.2
|
100.2
|
1.0
|
ND1
|
C:HIS144
|
2.3
|
90.9
|
1.0
|
CG
|
C:HIS144
|
2.9
|
90.9
|
1.0
|
CB
|
C:HIS144
|
3.0
|
90.9
|
1.0
|
CE1
|
C:HIS144
|
3.4
|
90.9
|
1.0
|
CB
|
C:ASP140
|
3.5
|
98.8
|
1.0
|
CB
|
C:ASP142
|
3.7
|
100.2
|
1.0
|
N
|
C:HIS144
|
3.8
|
90.9
|
1.0
|
CA
|
C:HIS144
|
4.0
|
90.9
|
1.0
|
CD2
|
C:HIS144
|
4.1
|
90.9
|
1.0
|
NE2
|
C:HIS144
|
4.3
|
90.9
|
1.0
|
N
|
C:ASP142
|
4.4
|
100.2
|
1.0
|
CA
|
C:ASP142
|
4.4
|
100.2
|
1.0
|
O
|
C:HIS144
|
4.5
|
90.9
|
1.0
|
C
|
C:ASP142
|
4.6
|
100.2
|
1.0
|
CA
|
C:ASP140
|
4.6
|
98.8
|
1.0
|
N
|
C:GLY143
|
4.7
|
90.7
|
1.0
|
C
|
C:HIS144
|
4.8
|
90.9
|
1.0
|
N
|
C:ASP140
|
4.9
|
98.8
|
1.0
|
C
|
C:ASP140
|
4.9
|
98.8
|
1.0
|
|
Zinc binding site 7 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 7 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn502
b:127.8
occ:1.00
|
ND1
|
D:HIS163
|
2.3
|
86.4
|
1.0
|
NE2
|
D:HIS168
|
2.3
|
93.8
|
1.0
|
CD2
|
D:HIS168
|
2.9
|
93.8
|
1.0
|
CG
|
D:HIS163
|
3.3
|
86.4
|
1.0
|
CE1
|
D:HIS163
|
3.3
|
86.4
|
1.0
|
CE1
|
D:HIS168
|
3.4
|
93.8
|
1.0
|
CB
|
D:HIS163
|
3.5
|
86.4
|
1.0
|
O
|
D:ARG166
|
4.0
|
86.0
|
1.0
|
CG
|
D:HIS168
|
4.1
|
93.8
|
1.0
|
ND1
|
D:HIS168
|
4.3
|
93.8
|
1.0
|
NE2
|
D:HIS163
|
4.4
|
86.4
|
1.0
|
CD2
|
D:HIS163
|
4.4
|
86.4
|
1.0
|
|
Zinc binding site 8 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 8 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Zn503
b:127.3
occ:1.00
|
OD1
|
D:ASP142
|
2.0
|
96.8
|
1.0
|
OD1
|
D:ASP140
|
2.0
|
96.1
|
1.0
|
OD2
|
D:ASP142
|
2.0
|
96.8
|
1.0
|
OD2
|
D:ASP140
|
2.0
|
96.1
|
1.0
|
CG
|
D:ASP140
|
2.1
|
96.1
|
1.0
|
CG
|
D:ASP142
|
2.2
|
96.8
|
1.0
|
ND1
|
D:HIS144
|
2.3
|
88.5
|
1.0
|
CG
|
D:HIS144
|
2.9
|
88.5
|
1.0
|
CB
|
D:HIS144
|
3.0
|
88.5
|
1.0
|
CE1
|
D:HIS144
|
3.4
|
88.5
|
1.0
|
CB
|
D:ASP140
|
3.5
|
96.1
|
1.0
|
CB
|
D:ASP142
|
3.7
|
96.8
|
1.0
|
N
|
D:HIS144
|
3.8
|
88.5
|
1.0
|
CA
|
D:HIS144
|
4.0
|
88.5
|
1.0
|
CD2
|
D:HIS144
|
4.1
|
88.5
|
1.0
|
NE2
|
D:HIS144
|
4.3
|
88.5
|
1.0
|
N
|
D:ASP142
|
4.4
|
96.8
|
1.0
|
CA
|
D:ASP142
|
4.4
|
96.8
|
1.0
|
O
|
D:HIS144
|
4.5
|
88.5
|
1.0
|
C
|
D:ASP142
|
4.6
|
96.8
|
1.0
|
CA
|
D:ASP140
|
4.6
|
96.1
|
1.0
|
N
|
D:GLY143
|
4.7
|
87.6
|
1.0
|
C
|
D:HIS144
|
4.8
|
88.5
|
1.0
|
N
|
D:ASP140
|
4.9
|
96.1
|
1.0
|
C
|
D:ASP140
|
4.9
|
96.1
|
1.0
|
|
Zinc binding site 9 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 9 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn502
b:129.9
occ:1.00
|
ND1
|
E:HIS163
|
2.3
|
88.2
|
1.0
|
NE2
|
E:HIS168
|
2.3
|
92.5
|
1.0
|
CD2
|
E:HIS168
|
2.9
|
92.5
|
1.0
|
CG
|
E:HIS163
|
3.3
|
88.2
|
1.0
|
CE1
|
E:HIS163
|
3.3
|
88.2
|
1.0
|
CE1
|
E:HIS168
|
3.4
|
92.5
|
1.0
|
CB
|
E:HIS163
|
3.5
|
88.2
|
1.0
|
O
|
E:ARG166
|
4.0
|
86.2
|
1.0
|
CG
|
E:HIS168
|
4.1
|
92.5
|
1.0
|
ND1
|
E:HIS168
|
4.3
|
92.5
|
1.0
|
NE2
|
E:HIS163
|
4.4
|
88.2
|
1.0
|
CD2
|
E:HIS163
|
4.4
|
88.2
|
1.0
|
|
Zinc binding site 10 out
of 10 in 8yx6
Go back to
Zinc Binding Sites List in 8yx6
Zinc binding site 10 out
of 10 in the Structure of A Cys-Loop Receptor in Zinc Binding State
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 10 of Structure of A Cys-Loop Receptor in Zinc Binding State within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Zn503
b:126.2
occ:1.00
|
OD1
|
E:ASP142
|
2.0
|
96.8
|
1.0
|
OD1
|
E:ASP140
|
2.0
|
96.2
|
1.0
|
OD2
|
E:ASP142
|
2.0
|
96.8
|
1.0
|
OD2
|
E:ASP140
|
2.0
|
96.2
|
1.0
|
CG
|
E:ASP140
|
2.1
|
96.2
|
1.0
|
CG
|
E:ASP142
|
2.2
|
96.8
|
1.0
|
ND1
|
E:HIS144
|
2.3
|
88.6
|
1.0
|
CG
|
E:HIS144
|
2.9
|
88.6
|
1.0
|
CB
|
E:HIS144
|
3.0
|
88.6
|
1.0
|
CE1
|
E:HIS144
|
3.4
|
88.6
|
1.0
|
CB
|
E:ASP140
|
3.5
|
96.2
|
1.0
|
CB
|
E:ASP142
|
3.7
|
96.8
|
1.0
|
N
|
E:HIS144
|
3.8
|
88.6
|
1.0
|
CA
|
E:HIS144
|
4.0
|
88.6
|
1.0
|
CD2
|
E:HIS144
|
4.1
|
88.6
|
1.0
|
NE2
|
E:HIS144
|
4.3
|
88.6
|
1.0
|
N
|
E:ASP142
|
4.4
|
96.8
|
1.0
|
CA
|
E:ASP142
|
4.4
|
96.8
|
1.0
|
O
|
E:HIS144
|
4.5
|
88.6
|
1.0
|
C
|
E:ASP142
|
4.6
|
96.8
|
1.0
|
CA
|
E:ASP140
|
4.6
|
96.2
|
1.0
|
N
|
E:GLY143
|
4.7
|
87.5
|
1.0
|
C
|
E:HIS144
|
4.8
|
88.6
|
1.0
|
N
|
E:ASP140
|
4.9
|
96.2
|
1.0
|
C
|
E:ASP140
|
4.9
|
96.2
|
1.0
|
|
Reference:
X.H.Lu,
X.Yang,
Y.Q.Shen.
Structure of A Cys-Loop Receptor in Zinc Binding State To Be Published.
Page generated: Sun Feb 9 00:56:48 2025
|