Zinc in PDB 8yqy: Asfv Rna Polymerase-M1249L Complex Complete
Enzymatic activity of Asfv Rna Polymerase-M1249L Complex Complete
All present enzymatic activity of Asfv Rna Polymerase-M1249L Complex Complete:
2.7.7.6;
Other elements in 8yqy:
The structure of Asfv Rna Polymerase-M1249L Complex Complete also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Asfv Rna Polymerase-M1249L Complex Complete
(pdb code 8yqy). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 9 binding sites of Zinc where determined in the
Asfv Rna Polymerase-M1249L Complex Complete, PDB code: 8yqy:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
Zinc binding site 1 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 1 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn2002
b:87.6
occ:1.00
|
NE2
|
A:HIS72
|
2.1
|
52.5
|
1.0
|
SG
|
A:CYS62
|
2.3
|
49.4
|
1.0
|
SG
|
A:CYS59
|
2.3
|
63.6
|
1.0
|
SG
|
A:CYS69
|
2.3
|
54.4
|
1.0
|
CD2
|
A:HIS72
|
3.0
|
52.3
|
1.0
|
CB
|
A:CYS59
|
3.0
|
44.3
|
1.0
|
CE1
|
A:HIS72
|
3.1
|
48.5
|
1.0
|
CB
|
A:CYS69
|
3.4
|
51.4
|
1.0
|
CB
|
A:CYS62
|
3.6
|
43.5
|
1.0
|
N
|
A:CYS62
|
3.9
|
47.1
|
1.0
|
CG
|
A:HIS72
|
4.1
|
49.8
|
1.0
|
ND1
|
A:HIS72
|
4.1
|
46.7
|
1.0
|
CA
|
A:GLY51
|
4.1
|
49.1
|
1.0
|
CA
|
A:CYS69
|
4.2
|
44.5
|
1.0
|
CA
|
A:CYS62
|
4.3
|
43.6
|
1.0
|
CA
|
A:CYS59
|
4.5
|
46.4
|
1.0
|
N
|
A:GLY71
|
4.5
|
45.4
|
1.0
|
CB
|
A:THR61
|
4.6
|
44.9
|
1.0
|
N
|
A:GLY51
|
4.7
|
47.9
|
1.0
|
C
|
A:CYS69
|
4.8
|
49.1
|
1.0
|
N
|
A:MET70
|
4.8
|
42.8
|
1.0
|
CA
|
A:GLY71
|
4.9
|
39.8
|
1.0
|
C
|
A:THR61
|
5.0
|
47.7
|
1.0
|
|
Zinc binding site 2 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 2 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn2003
b:153.3
occ:1.00
|
SG
|
A:CYS102
|
2.3
|
86.2
|
1.0
|
SG
|
A:CYS134
|
2.3
|
98.2
|
1.0
|
SG
|
A:CYS99
|
2.3
|
87.1
|
1.0
|
SG
|
A:CYS137
|
2.3
|
100.9
|
1.0
|
CB
|
A:CYS134
|
2.9
|
96.0
|
1.0
|
CB
|
A:CYS99
|
3.0
|
80.4
|
1.0
|
CB
|
A:CYS102
|
3.4
|
77.8
|
1.0
|
CB
|
A:CYS137
|
3.6
|
95.4
|
1.0
|
N
|
A:CYS102
|
3.9
|
80.8
|
1.0
|
CA
|
A:CYS102
|
4.2
|
80.8
|
1.0
|
N
|
A:CYS137
|
4.2
|
97.3
|
1.0
|
CA
|
A:CYS134
|
4.4
|
94.0
|
1.0
|
CA
|
A:CYS137
|
4.5
|
96.1
|
1.0
|
CB
|
A:ALA139
|
4.5
|
89.0
|
1.0
|
CA
|
A:CYS99
|
4.5
|
80.2
|
1.0
|
CG2
|
A:VAL136
|
4.5
|
96.2
|
1.0
|
C
|
A:ASN101
|
4.8
|
77.8
|
1.0
|
N
|
A:GLY103
|
4.9
|
75.6
|
1.0
|
C
|
A:CYS102
|
4.9
|
82.4
|
1.0
|
CB
|
A:ASN101
|
4.9
|
75.6
|
1.0
|
N
|
A:ALA139
|
5.0
|
91.6
|
1.0
|
N
|
A:ASN101
|
5.0
|
76.0
|
1.0
|
C
|
A:CYS137
|
5.0
|
96.1
|
1.0
|
|
Zinc binding site 3 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 3 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1301
b:93.0
occ:1.00
|
SG
|
B:CYS1198
|
2.3
|
67.1
|
1.0
|
SG
|
B:CYS1180
|
2.3
|
57.1
|
1.0
|
SG
|
B:CYS1183
|
2.3
|
61.6
|
1.0
|
SG
|
B:CYS1201
|
2.3
|
71.2
|
1.0
|
CB
|
B:CYS1180
|
3.1
|
35.1
|
1.0
|
CB
|
B:CYS1198
|
3.3
|
62.1
|
1.0
|
CB
|
B:CYS1201
|
3.7
|
73.9
|
1.0
|
CB
|
B:CYS1183
|
3.8
|
45.4
|
1.0
|
N
|
B:CYS1201
|
4.1
|
70.0
|
1.0
|
N
|
B:CYS1183
|
4.2
|
39.5
|
1.0
|
CA
|
B:ALA1205
|
4.5
|
51.7
|
1.0
|
CA
|
B:CYS1201
|
4.5
|
75.3
|
1.0
|
CA
|
B:CYS1180
|
4.5
|
34.8
|
1.0
|
CB
|
B:ALA1205
|
4.6
|
46.8
|
1.0
|
CA
|
B:CYS1183
|
4.6
|
41.8
|
1.0
|
CA
|
B:CYS1198
|
4.6
|
61.9
|
1.0
|
CB
|
B:ASN1200
|
4.6
|
61.9
|
1.0
|
CB
|
B:ASN1182
|
4.7
|
50.5
|
1.0
|
O
|
B:CYS1198
|
4.8
|
67.8
|
1.0
|
C
|
B:CYS1198
|
4.9
|
65.5
|
1.0
|
C
|
B:ASN1200
|
4.9
|
68.4
|
1.0
|
N
|
B:ASN1200
|
5.0
|
71.3
|
1.0
|
|
Zinc binding site 4 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 4 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn201
b:132.5
occ:1.00
|
SG
|
G:CYS76
|
2.3
|
72.7
|
1.0
|
SG
|
G:CYS98
|
2.3
|
69.7
|
1.0
|
SG
|
G:CYS96
|
2.3
|
71.6
|
1.0
|
SG
|
G:CYS73
|
2.3
|
67.5
|
1.0
|
CB
|
G:CYS96
|
3.2
|
53.2
|
1.0
|
CB
|
G:CYS73
|
3.3
|
63.3
|
1.0
|
CB
|
G:CYS98
|
3.4
|
64.5
|
1.0
|
CB
|
G:CYS76
|
3.6
|
72.3
|
1.0
|
N
|
G:CYS76
|
3.9
|
70.1
|
1.0
|
N
|
G:CYS98
|
4.1
|
60.8
|
1.0
|
CA
|
G:CYS76
|
4.3
|
71.1
|
1.0
|
CA
|
G:CYS98
|
4.3
|
61.4
|
1.0
|
CB
|
G:TYR100
|
4.4
|
55.6
|
1.0
|
CB
|
G:ASN75
|
4.5
|
70.3
|
1.0
|
CA
|
G:CYS96
|
4.6
|
51.7
|
1.0
|
CA
|
G:CYS73
|
4.7
|
64.9
|
1.0
|
N
|
G:ARG97
|
4.8
|
51.3
|
1.0
|
CB
|
G:LEU78
|
4.8
|
57.3
|
1.0
|
C
|
G:CYS96
|
4.8
|
54.5
|
1.0
|
C
|
G:ASN75
|
4.9
|
69.7
|
1.0
|
C
|
G:CYS76
|
5.0
|
71.0
|
1.0
|
|
Zinc binding site 5 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 5 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Zn202
b:135.6
occ:1.00
|
SG
|
G:CYS24
|
2.3
|
77.3
|
1.0
|
SG
|
G:CYS7
|
2.3
|
77.8
|
1.0
|
SG
|
G:CYS26
|
2.3
|
88.7
|
1.0
|
SG
|
G:CYS4
|
2.3
|
72.8
|
1.0
|
CB
|
G:CYS4
|
3.1
|
69.8
|
1.0
|
CB
|
G:CYS24
|
3.3
|
79.8
|
1.0
|
CB
|
G:CYS26
|
3.5
|
82.4
|
1.0
|
CB
|
G:CYS7
|
3.8
|
69.9
|
1.0
|
N
|
G:CYS7
|
4.0
|
68.6
|
1.0
|
N
|
G:CYS26
|
4.2
|
81.9
|
1.0
|
CA
|
G:CYS26
|
4.4
|
83.8
|
1.0
|
CA
|
G:CYS7
|
4.5
|
65.5
|
1.0
|
CB
|
G:GLU28
|
4.5
|
79.7
|
1.0
|
CB
|
G:ALA6
|
4.6
|
69.8
|
1.0
|
CA
|
G:CYS4
|
4.6
|
66.5
|
1.0
|
CA
|
G:CYS24
|
4.7
|
76.4
|
1.0
|
CB
|
G:SER9
|
4.7
|
68.7
|
1.0
|
N
|
G:SER25
|
4.8
|
79.6
|
1.0
|
CD1
|
J:TYR1078
|
4.8
|
74.4
|
1.0
|
OG
|
G:SER9
|
5.0
|
68.7
|
1.0
|
C
|
G:CYS7
|
5.0
|
66.7
|
1.0
|
|
Zinc binding site 6 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 6 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Zn101
b:80.4
occ:1.00
|
SG
|
H:CYS10
|
2.3
|
43.4
|
1.0
|
SG
|
H:CYS66
|
2.3
|
47.0
|
1.0
|
SG
|
H:CYS65
|
2.3
|
30.2
|
1.0
|
SG
|
H:CYS7
|
2.3
|
38.0
|
1.0
|
CB
|
H:CYS7
|
3.1
|
11.8
|
1.0
|
N
|
H:CYS66
|
3.3
|
28.8
|
1.0
|
CB
|
H:CYS65
|
3.5
|
23.3
|
1.0
|
CB
|
H:CYS66
|
3.6
|
25.4
|
1.0
|
CA
|
H:CYS66
|
3.6
|
19.2
|
1.0
|
CB
|
H:CYS10
|
3.7
|
24.7
|
1.0
|
C
|
H:CYS65
|
3.9
|
32.5
|
1.0
|
N
|
H:CYS10
|
3.9
|
18.9
|
1.0
|
NE
|
H:ARG63
|
4.0
|
41.7
|
1.0
|
CA
|
H:CYS65
|
4.2
|
21.7
|
1.0
|
CA
|
H:CYS10
|
4.4
|
22.6
|
1.0
|
CB
|
H:THR9
|
4.5
|
28.2
|
1.0
|
CA
|
H:CYS7
|
4.6
|
22.8
|
1.0
|
O
|
H:CYS65
|
4.6
|
37.1
|
1.0
|
CD
|
H:ARG63
|
4.7
|
37.0
|
1.0
|
N
|
H:GLY11
|
4.7
|
27.7
|
1.0
|
CB
|
H:PHE12
|
4.7
|
19.9
|
1.0
|
CB
|
H:ARG63
|
4.8
|
35.7
|
1.0
|
N
|
H:CYS65
|
4.8
|
28.9
|
1.0
|
N
|
H:PHE12
|
4.8
|
23.6
|
1.0
|
NH2
|
H:ARG63
|
4.8
|
33.9
|
1.0
|
CZ
|
H:ARG63
|
4.9
|
34.7
|
1.0
|
CG2
|
H:THR9
|
4.9
|
33.8
|
1.0
|
C
|
H:THR9
|
4.9
|
25.8
|
1.0
|
C
|
H:CYS10
|
5.0
|
32.6
|
1.0
|
|
Zinc binding site 7 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 7 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn1301
b:112.8
occ:1.00
|
ND1
|
J:HIS943
|
2.1
|
70.9
|
1.0
|
SG
|
J:CYS953
|
2.3
|
89.0
|
1.0
|
SG
|
J:CYS950
|
2.3
|
90.1
|
1.0
|
SG
|
J:CYS937
|
2.3
|
78.0
|
1.0
|
CE1
|
J:HIS943
|
2.5
|
69.6
|
1.0
|
CB
|
J:CYS950
|
3.2
|
88.2
|
1.0
|
CG
|
J:HIS943
|
3.4
|
70.1
|
1.0
|
CB
|
J:CYS937
|
3.6
|
64.6
|
1.0
|
CB
|
J:CYS953
|
3.6
|
84.1
|
1.0
|
N
|
J:CYS953
|
3.7
|
85.0
|
1.0
|
NE2
|
J:HIS943
|
3.8
|
71.2
|
1.0
|
CB
|
J:HIS943
|
4.1
|
70.4
|
1.0
|
CA
|
J:CYS953
|
4.2
|
85.2
|
1.0
|
CD2
|
J:HIS943
|
4.2
|
70.3
|
1.0
|
CA
|
J:HIS943
|
4.2
|
71.8
|
1.0
|
CA
|
J:CYS937
|
4.3
|
65.0
|
1.0
|
CB
|
J:LYS952
|
4.4
|
79.4
|
1.0
|
CD
|
J:PRO938
|
4.5
|
74.3
|
1.0
|
CB
|
J:LEU955
|
4.6
|
78.6
|
1.0
|
C
|
J:LYS952
|
4.7
|
81.0
|
1.0
|
CA
|
J:CYS950
|
4.7
|
88.1
|
1.0
|
C
|
J:CYS953
|
4.8
|
85.1
|
1.0
|
OH
|
J:TYR973
|
4.8
|
77.7
|
1.0
|
N
|
J:LYS952
|
4.8
|
80.8
|
1.0
|
CA
|
J:LYS952
|
4.9
|
79.3
|
1.0
|
O
|
J:CYS953
|
5.0
|
85.6
|
1.0
|
N
|
J:ASP944
|
5.0
|
83.9
|
1.0
|
|
Zinc binding site 8 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 8 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn1302
b:91.0
occ:1.00
|
SG
|
J:CYS901
|
2.3
|
70.4
|
1.0
|
SG
|
J:CYS898
|
2.3
|
71.3
|
1.0
|
ND1
|
J:HIS857
|
2.3
|
52.5
|
1.0
|
CE1
|
J:HIS857
|
3.0
|
54.7
|
1.0
|
CB
|
J:CYS898
|
3.4
|
59.0
|
1.0
|
CB
|
J:CYS901
|
3.4
|
71.5
|
1.0
|
CG
|
J:HIS857
|
3.4
|
47.0
|
1.0
|
N
|
J:CYS901
|
3.5
|
66.3
|
1.0
|
CA
|
J:HIS857
|
3.6
|
54.4
|
1.0
|
CB
|
J:HIS857
|
3.9
|
49.0
|
1.0
|
CB
|
J:VAL900
|
4.0
|
62.0
|
1.0
|
O
|
J:PRO856
|
4.0
|
53.9
|
1.0
|
CA
|
J:CYS901
|
4.0
|
65.3
|
1.0
|
NE2
|
J:HIS857
|
4.1
|
54.1
|
1.0
|
CB
|
J:ASP851
|
4.2
|
58.7
|
1.0
|
N
|
J:HIS857
|
4.3
|
54.4
|
1.0
|
CD2
|
J:HIS857
|
4.3
|
49.4
|
1.0
|
C
|
J:PRO856
|
4.4
|
46.4
|
1.0
|
N
|
J:LYS858
|
4.4
|
51.0
|
1.0
|
CG
|
J:ASP851
|
4.5
|
63.4
|
1.0
|
C
|
J:VAL900
|
4.5
|
60.9
|
1.0
|
CG1
|
J:VAL900
|
4.5
|
64.2
|
1.0
|
C
|
J:HIS857
|
4.6
|
55.1
|
1.0
|
CA
|
J:VAL900
|
4.6
|
61.8
|
1.0
|
OD2
|
J:ASP851
|
4.6
|
62.9
|
1.0
|
N
|
J:VAL900
|
4.7
|
67.4
|
1.0
|
CA
|
J:CYS898
|
4.8
|
63.5
|
1.0
|
CG2
|
J:VAL900
|
4.9
|
59.0
|
1.0
|
C
|
J:CYS901
|
4.9
|
67.2
|
1.0
|
O
|
J:LEU855
|
4.9
|
58.5
|
1.0
|
|
Zinc binding site 9 out
of 9 in 8yqy
Go back to
Zinc Binding Sites List in 8yqy
Zinc binding site 9 out
of 9 in the Asfv Rna Polymerase-M1249L Complex Complete
Mono view
Stereo pair view
|
A full contact list of Zinc with other atoms in the Zn binding
site number 9 of Asfv Rna Polymerase-M1249L Complex Complete within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn1303
b:137.9
occ:1.00
|
ND1
|
J:HIS403
|
2.3
|
89.7
|
1.0
|
SG
|
J:CYS442
|
2.3
|
102.3
|
1.0
|
SG
|
J:CYS401
|
2.3
|
90.5
|
1.0
|
CE1
|
J:HIS403
|
2.8
|
87.4
|
1.0
|
CB
|
J:CYS442
|
3.1
|
96.3
|
1.0
|
CG
|
J:HIS403
|
3.1
|
88.4
|
1.0
|
CB
|
J:CYS445
|
3.2
|
104.2
|
1.0
|
CB
|
J:CYS401
|
3.2
|
88.8
|
1.0
|
N
|
J:CYS445
|
3.7
|
103.4
|
1.0
|
CB
|
J:HIS403
|
3.7
|
86.5
|
1.0
|
NE2
|
J:HIS403
|
3.8
|
85.2
|
1.0
|
CD2
|
J:HIS403
|
3.9
|
85.0
|
1.0
|
CA
|
J:CYS445
|
4.0
|
103.5
|
1.0
|
CB
|
J:ALA444
|
4.2
|
95.7
|
1.0
|
C
|
J:ALA444
|
4.5
|
99.1
|
1.0
|
CA
|
J:CYS442
|
4.5
|
96.9
|
1.0
|
N
|
J:HIS403
|
4.5
|
85.7
|
1.0
|
SG
|
J:CYS445
|
4.6
|
107.4
|
1.0
|
CA
|
J:CYS401
|
4.7
|
90.2
|
1.0
|
CA
|
J:ALA444
|
4.8
|
97.3
|
1.0
|
CA
|
J:HIS403
|
4.8
|
87.0
|
1.0
|
N
|
J:ALA444
|
4.8
|
97.2
|
1.0
|
N
|
J:GLY446
|
4.9
|
99.4
|
1.0
|
C
|
J:CYS442
|
4.9
|
97.8
|
1.0
|
ND2
|
J:ASN399
|
5.0
|
93.3
|
1.0
|
|
Reference:
X.Y.Feng,
X.Y.Feng.
N/A N/A.
Page generated: Wed Nov 13 13:55:44 2024
|