Zinc in PDB 8xn5: Cryo-Em Structure of Sars-Cov-2 Omicron Eg.5.1 Spike Protein(6P) in Complex with Human ACE2

All present enzymatic activity of Cryo-Em Structure of Sars-Cov-2 Omicron Eg.5.1 Spike Protein(6P) in Complex with Human ACE2:
3.4.17.23;

The binding sites of Zinc atom in the Cryo-Em Structure of Sars-Cov-2 Omicron Eg.5.1 Spike Protein(6P) in Complex with Human ACE2 (pdb code 8xn5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Cryo-Em Structure of Sars-Cov-2 Omicron Eg.5.1 Spike Protein(6P) in Complex with Human ACE2, PDB code: 8xn5:

Zinc binding site 1 out of 1 in the Cryo-Em Structure of Sars-Cov-2 Omicron Eg.5.1 Spike Protein(6P) in Complex with Human ACE2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Sars-Cov-2 Omicron Eg.5.1 Spike Protein(6P) in Complex with Human ACE2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn706 b:30.0 occ:1.00 NE2 A:HIS378 2.0 123.1 1.0 NE2 A:HIS374 2.0 123.1 1.0 OE2 A:GLU402 2.1 123.1 1.0 CD2 A:HIS374 2.2 123.1 1.0 OE1 A:GLU402 2.2 123.1 1.0 CD A:GLU402 2.4 123.1 1.0 CE1 A:HIS378 2.6 123.1 1.0 CD2 A:HIS378 3.3 123.1 1.0 CE1 A:HIS374 3.3 123.1 1.0 CG A:HIS374 3.5 123.1 1.0 ND1 A:HIS378 3.8 123.1 1.0 CG A:GLU402 4.0 123.1 1.0 ND1 A:HIS374 4.0 123.1 1.0 OE2 A:GLU375 4.1 123.1 1.0 CG A:HIS378 4.2 123.1 1.0 CB A:HIS374 4.7 123.1 1.0 CB A:GLU402 4.8 123.1 1.0 CA A:GLU402 4.8 123.1 1.0 CD A:GLU375 4.9 123.1 1.0 O A:HIS374 5.0 123.1 1.0

L.J.Li, Z.P.Xu, K.F.Liu, G.F.Gao. Structural Basis of Receptor Binding and Immune Escape For Sars-Cov-2 Omicron Ba.2.86, Eg.5, Eg.5.1 and Hv.1 Sub-Variants To Be Published.