Zinc in PDB 8xj6: The Cryo-Em Structure of Mpxv E5 Apo Conformation

The binding sites of Zinc atom in the The Cryo-Em Structure of Mpxv E5 Apo Conformation (pdb code 8xj6). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the The Cryo-Em Structure of Mpxv E5 Apo Conformation, PDB code: 8xj6:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the The Cryo-Em Structure of Mpxv E5 Apo Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of The Cryo-Em Structure of Mpxv E5 Apo Conformation within 5.0Å range: probe atom residue distance (Å) B Occ E:Zn802 b:30.0 occ:1.00 SG E:CYS285 2.5 145.0 1.0 ND1 E:HIS290 2.5 143.6 1.0 SG E:CYS314 2.7 136.2 1.0 CB E:CYS285 2.8 145.0 1.0 CE1 E:HIS290 2.8 143.6 1.0 SG E:CYS282 2.9 151.9 1.0 CE1 E:HIS294 3.5 134.7 1.0 N E:CYS285 3.6 145.0 1.0 NE2 E:HIS294 3.6 134.7 1.0 CB E:CYS314 3.6 136.2 1.0 CA E:CYS285 3.8 145.0 1.0 CB E:CYS282 3.8 151.9 1.0 CG E:HIS290 3.8 143.6 1.0 NE2 E:HIS290 4.1 143.6 1.0 CA E:CYS314 4.5 136.2 1.0 CB E:LEU284 4.5 141.9 1.0 CB E:HIS290 4.5 143.6 1.0 C E:LEU284 4.6 141.9 1.0 CD2 E:HIS290 4.6 143.6 1.0 ND1 E:HIS294 4.8 134.7 1.0 C E:CYS285 4.8 145.0 1.0 O E:SER313 4.9 134.6 1.0 CA E:LEU284 5.0 141.9 1.0 CD2 E:HIS294 5.0 134.7 1.0

Zinc binding site 2 out of 2 in the The Cryo-Em Structure of Mpxv E5 Apo Conformation


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of The Cryo-Em Structure of Mpxv E5 Apo Conformation within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn802 b:30.0 occ:1.00 SG F:CYS285 2.2 151.9 1.0 SG F:CYS314 2.4 142.7 1.0 SG F:CYS282 2.4 154.6 1.0 CB F:CYS285 3.0 151.9 1.0 CB F:CYS282 3.0 154.6 1.0 CB F:CYS314 3.2 142.7 1.0 CA F:CYS314 4.0 142.7 1.0 N F:CYS285 4.1 151.9 1.0 CA F:CYS285 4.1 151.9 1.0 CA F:CYS282 4.3 154.6 1.0 O F:CYS282 4.4 154.6 1.0 CE1 F:HIS294 4.5 146.4 1.0 NE2 F:HIS294 4.5 146.4 1.0 CB F:HIS290 4.6 151.7 1.0 CB F:LYS287 4.6 153.6 1.0 C F:CYS282 4.6 154.6 1.0 C F:CYS285 4.8 151.9 1.0 N F:CYS282 4.8 154.6 1.0 O F:SER313 4.9 145.0 1.0 N F:CYS314 4.9 142.7 1.0 N F:LYS287 5.0 153.6 1.0 C F:LEU284 5.0 148.1 1.0

J.Gan, W.Zhang. Structural and Functional Insights Into the Helicase Protein E5 of Mpox Virus. Cell Discov 2024.
ISSN: ESSN 2056-5968