Zinc in PDB 8v35: Crystal Structure of Hpsn From Cupriavidus Pinatubonensis

The structure of Crystal Structure of Hpsn From Cupriavidus Pinatubonensis, PDB code: 8v35 was solved by M.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.96 / 1.94
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	77.032, 87.767, 134.8, 90, 90, 90
R / Rfree (%)	21.9 / 26.2

The binding sites of Zinc atom in the Crystal Structure of Hpsn From Cupriavidus Pinatubonensis (pdb code 8v35). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Crystal Structure of Hpsn From Cupriavidus Pinatubonensis, PDB code: 8v35:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Crystal Structure of Hpsn From Cupriavidus Pinatubonensis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Hpsn From Cupriavidus Pinatubonensis within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn502 b:45.0 occ:1.00 O A:HOH678 2.0 41.1 1.0 NE2 B:HIS411 2.0 42.1 1.0 NE2 A:HIS251 2.1 45.2 1.0 NE2 A:HIS126 2.1 42.6 1.0 O B:HOH676 2.2 44.0 1.0 OE1 A:GLN248 2.2 44.5 1.0 CE1 B:HIS411 2.9 43.8 1.0 CE1 A:HIS251 3.1 47.6 1.0 CD2 B:HIS411 3.1 38.8 1.0 CD2 A:HIS126 3.1 43.7 1.0 CE1 A:HIS126 3.1 45.8 1.0 CD2 A:HIS251 3.1 47.0 1.0 CD A:GLN248 3.1 44.8 1.0 NE2 A:GLN248 3.4 46.0 1.0 ND1 B:HIS411 4.1 45.5 1.0 CG B:HIS411 4.2 41.7 1.0 ND1 A:HIS251 4.2 47.7 1.0 ND1 A:HIS126 4.2 43.4 1.0 O A:HOH682 4.3 40.6 1.0 CG A:HIS126 4.3 45.1 1.0 CG A:HIS251 4.3 48.6 1.0 CG A:GLN248 4.5 45.9 1.0 OG A:SER226 4.6 75.0 1.0 CB A:SER226 4.8 71.4 1.0

Zinc binding site 2 out of 2 in the Crystal Structure of Hpsn From Cupriavidus Pinatubonensis


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Crystal Structure of Hpsn From Cupriavidus Pinatubonensis within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn501 b:54.1 occ:1.00 O A:HOH690 2.0 56.5 1.0 NE2 B:HIS251 2.0 62.1 1.0 O B:HOH650 2.1 53.9 1.0 NE2 A:HIS411 2.1 53.3 1.0 NE2 B:HIS126 2.2 48.0 1.0 OE1 B:GLN248 2.3 48.1 1.0 CE1 B:HIS251 3.0 60.3 1.0 CD2 B:HIS251 3.1 57.2 1.0 CE1 A:HIS411 3.1 54.5 1.0 CD B:GLN248 3.1 53.0 1.0 CD2 B:HIS126 3.2 49.5 1.0 CD2 A:HIS411 3.2 53.8 1.0 CE1 B:HIS126 3.2 49.3 1.0 NE2 B:GLN248 3.3 54.6 1.0 ND1 B:HIS251 4.1 64.3 1.0 OG B:SER226 4.1 88.0 1.0 CG B:HIS251 4.2 61.1 1.0 ND1 A:HIS411 4.2 53.0 1.0 CG A:HIS411 4.3 52.2 1.0 ND1 B:HIS126 4.3 44.3 1.0 CG B:HIS126 4.3 49.5 1.0 CG B:GLN248 4.5 56.1 1.0 CB B:SER226 4.6 86.8 1.0

L.Burchill, A.Kaur, A.Nastasovici, M.Lee, S.J.Williams. Structural and Kinetic Insights Into the Stereospecific Oxidation of R -2,3-Dihydroxypropanesulfonate By Dhps-3-Dehydrogenase From Cupriavidus Pinatubonensis. Chem Sci 2024.
ISSN: ISSN 2041-6520
PubMed: 39263660
DOI: 10.1039/D4SC05114A