Zinc in PDB 8tvs: Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
Enzymatic activity of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
All present enzymatic activity of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26:
2.7.7.6;
Other elements in 8tvs:
The structure of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
(pdb code 8tvs). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the
Cryo-Em Structure of Backtracked Pol II in Complex with RAD26, PDB code: 8tvs:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Zinc binding site 1 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 1 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1801
b:205.6
occ:1.00
|
H
|
A:CYS110
|
1.8
|
172.5
|
1.0
|
|
O
|
A:CYS107
|
2.0
|
172.2
|
1.0
|
|
N
|
A:CYS110
|
2.1
|
172.5
|
1.0
|
|
SG
|
A:CYS167
|
2.3
|
173.2
|
1.0
|
|
HB2
|
A:CYS110
|
2.4
|
172.5
|
1.0
|
|
O
|
A:MET108
|
2.4
|
168.5
|
1.0
|
|
C
|
A:MET108
|
2.4
|
168.5
|
1.0
|
|
C
|
A:HIS109
|
2.6
|
167.6
|
1.0
|
|
C
|
A:CYS107
|
2.6
|
172.2
|
1.0
|
|
HB3
|
A:CYS110
|
2.6
|
172.5
|
1.0
|
|
N
|
A:HIS109
|
2.7
|
167.6
|
1.0
|
|
CB
|
A:CYS110
|
2.8
|
172.5
|
1.0
|
|
CA
|
A:CYS110
|
2.9
|
172.5
|
1.0
|
|
N
|
A:MET108
|
3.1
|
168.5
|
1.0
|
|
CA
|
A:HIS109
|
3.1
|
167.6
|
1.0
|
|
HB3
|
A:CYS107
|
3.2
|
172.2
|
1.0
|
|
CA
|
A:MET108
|
3.3
|
168.5
|
1.0
|
|
H
|
A:HIS109
|
3.3
|
167.6
|
1.0
|
|
HB2
|
A:HIS109
|
3.4
|
167.6
|
1.0
|
|
O
|
A:HIS109
|
3.4
|
167.6
|
1.0
|
|
HA
|
A:CYS110
|
3.5
|
172.5
|
1.0
|
|
HB2
|
A:CYS107
|
3.6
|
172.2
|
1.0
|
|
HB2
|
A:CYS167
|
3.6
|
173.2
|
1.0
|
|
CB
|
A:CYS107
|
3.6
|
172.2
|
1.0
|
|
CB
|
A:CYS167
|
3.7
|
173.2
|
1.0
|
|
CA
|
A:CYS107
|
3.7
|
172.2
|
1.0
|
|
H
|
A:MET108
|
3.7
|
168.5
|
1.0
|
|
H
|
A:GLY111
|
3.8
|
161.4
|
1.0
|
|
CB
|
A:HIS109
|
3.8
|
167.6
|
1.0
|
|
HB2
|
A:MET108
|
3.8
|
168.5
|
1.0
|
|
HA
|
A:HIS109
|
3.9
|
167.6
|
1.0
|
|
HA
|
A:MET108
|
4.0
|
168.5
|
1.0
|
|
C
|
A:CYS110
|
4.1
|
172.5
|
1.0
|
|
CB
|
A:MET108
|
4.1
|
168.5
|
1.0
|
|
HB3
|
A:CYS167
|
4.2
|
173.2
|
1.0
|
|
N
|
A:GLY111
|
4.3
|
161.4
|
1.0
|
|
H
|
A:CYS167
|
4.3
|
173.2
|
1.0
|
|
HA
|
A:CYS107
|
4.4
|
172.2
|
1.0
|
|
SG
|
A:CYS110
|
4.5
|
172.5
|
1.0
|
|
HB3
|
A:MET108
|
4.5
|
168.5
|
1.0
|
|
HB3
|
A:HIS109
|
4.5
|
167.6
|
1.0
|
|
N
|
A:CYS107
|
4.6
|
172.2
|
1.0
|
|
H
|
A:CYS107
|
4.6
|
172.2
|
1.0
|
|
CG
|
A:HIS109
|
4.6
|
167.6
|
1.0
|
|
N
|
A:CYS167
|
4.8
|
173.2
|
1.0
|
|
CA
|
A:CYS167
|
4.8
|
173.2
|
1.0
|
|
HB2
|
A:CYS148
|
4.8
|
174.7
|
1.0
|
|
HE21
|
A:GLN171
|
4.8
|
168.8
|
1.0
|
|
SG
|
A:CYS148
|
4.8
|
174.7
|
1.0
|
|
HG
|
A:CYS110
|
4.9
|
172.5
|
1.0
|
|
HG12
|
A:VAL106
|
4.9
|
162.5
|
1.0
|
|
H
|
A:LYS112
|
5.0
|
163.1
|
1.0
|
|
HA
|
A:CYS167
|
5.0
|
173.2
|
1.0
|
|
HD2
|
A:HIS109
|
5.0
|
167.6
|
1.0
|
|
Zinc binding site 2 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 2 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1802
b:167.6
occ:1.00
|
HB2
|
A:CYS70
|
1.4
|
129.4
|
1.0
|
|
O
|
A:CYS67
|
2.0
|
125.5
|
1.0
|
|
CB
|
A:CYS70
|
2.0
|
129.4
|
1.0
|
|
HB3
|
A:CYS67
|
2.1
|
125.5
|
1.0
|
|
NE2
|
A:HIS80
|
2.3
|
118.5
|
1.0
|
|
SG
|
A:CYS77
|
2.3
|
110.3
|
1.0
|
|
SG
|
A:CYS70
|
2.3
|
129.4
|
1.0
|
|
HB3
|
A:CYS70
|
2.4
|
129.4
|
1.0
|
|
HB2
|
A:CYS67
|
2.7
|
125.5
|
1.0
|
|
CB
|
A:CYS67
|
2.8
|
125.5
|
1.0
|
|
C
|
A:CYS67
|
3.0
|
125.5
|
1.0
|
|
HE1
|
A:HIS80
|
3.0
|
118.5
|
1.0
|
|
CE1
|
A:HIS80
|
3.0
|
118.5
|
1.0
|
|
H
|
A:CYS70
|
3.3
|
129.4
|
1.0
|
|
CA
|
A:CYS70
|
3.4
|
129.4
|
1.0
|
|
CD2
|
A:HIS80
|
3.5
|
118.5
|
1.0
|
|
CA
|
A:CYS67
|
3.5
|
125.5
|
1.0
|
|
HB3
|
A:GLN68
|
3.7
|
123.9
|
1.0
|
|
N
|
A:CYS70
|
3.7
|
129.4
|
1.0
|
|
HD2
|
A:HIS80
|
3.8
|
118.5
|
1.0
|
|
CB
|
A:CYS77
|
4.0
|
110.3
|
1.0
|
|
HA
|
A:CYS67
|
4.0
|
125.5
|
1.0
|
|
O
|
A:PRO78
|
4.0
|
104.4
|
1.0
|
|
HA
|
A:CYS70
|
4.0
|
129.4
|
1.0
|
|
C
|
A:CYS70
|
4.1
|
129.4
|
1.0
|
|
N
|
A:GLN68
|
4.2
|
123.9
|
1.0
|
|
HB2
|
A:CYS77
|
4.2
|
110.3
|
1.0
|
|
ND1
|
A:HIS80
|
4.3
|
118.5
|
1.0
|
|
O
|
A:LYS66
|
4.3
|
121.9
|
1.0
|
|
SG
|
A:CYS67
|
4.3
|
125.5
|
1.0
|
|
HB3
|
A:CYS77
|
4.3
|
110.3
|
1.0
|
|
HG
|
A:CYS67
|
4.4
|
125.5
|
1.0
|
|
CG
|
A:HIS80
|
4.5
|
118.5
|
1.0
|
|
CB
|
A:GLN68
|
4.5
|
123.9
|
1.0
|
|
O
|
A:GLN68
|
4.6
|
123.9
|
1.0
|
|
C
|
A:GLN68
|
4.6
|
123.9
|
1.0
|
|
N
|
A:CYS67
|
4.6
|
125.5
|
1.0
|
|
N
|
A:GLN71
|
4.6
|
124.5
|
1.0
|
|
H
|
A:GLN71
|
4.6
|
124.5
|
1.0
|
|
CA
|
A:GLN68
|
4.7
|
123.9
|
1.0
|
|
O
|
A:GLN71
|
4.7
|
124.5
|
1.0
|
|
O
|
A:CYS70
|
4.7
|
129.4
|
1.0
|
|
HB2
|
A:GLN68
|
4.8
|
123.9
|
1.0
|
|
HD12
|
B:ILE1172
|
4.8
|
119.6
|
1.0
|
|
HD2
|
A:PRO78
|
4.9
|
104.4
|
1.0
|
|
C
|
A:LYS66
|
4.9
|
121.9
|
1.0
|
|
H
|
A:GLN68
|
4.9
|
123.9
|
1.0
|
|
HD1
|
A:HIS80
|
5.0
|
118.5
|
1.0
|
|
Zinc binding site 3 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 3 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1301
b:181.9
occ:1.00
|
HB3
|
B:CYS1163
|
1.7
|
132.7
|
1.0
|
|
HB2
|
B:CYS1166
|
2.1
|
131.6
|
1.0
|
|
CB
|
B:CYS1163
|
2.2
|
132.7
|
1.0
|
|
SG
|
B:CYS1185
|
2.3
|
129.5
|
1.0
|
|
SG
|
B:CYS1163
|
2.3
|
132.7
|
1.0
|
|
SG
|
B:CYS1182
|
2.3
|
127.4
|
1.0
|
|
HB2
|
B:CYS1163
|
2.4
|
132.7
|
1.0
|
|
H
|
B:CYS1166
|
2.7
|
131.6
|
1.0
|
|
CB
|
B:CYS1166
|
3.0
|
131.6
|
1.0
|
|
O
|
B:CYS1166
|
3.1
|
131.6
|
1.0
|
|
N
|
B:CYS1166
|
3.4
|
131.6
|
1.0
|
|
CB
|
B:CYS1185
|
3.5
|
129.5
|
1.0
|
|
HB2
|
B:CYS1185
|
3.6
|
129.5
|
1.0
|
|
CA
|
B:CYS1166
|
3.6
|
131.6
|
1.0
|
|
HB3
|
B:CYS1166
|
3.6
|
131.6
|
1.0
|
|
CA
|
B:CYS1163
|
3.6
|
132.7
|
1.0
|
|
CB
|
B:CYS1182
|
3.7
|
127.4
|
1.0
|
|
C
|
B:CYS1166
|
3.7
|
131.6
|
1.0
|
|
HB3
|
B:CYS1185
|
3.8
|
129.5
|
1.0
|
|
HG1
|
B:THR1170
|
3.8
|
119.7
|
1.0
|
|
HB3
|
B:CYS1182
|
3.8
|
127.4
|
1.0
|
|
HB2
|
B:CYS1182
|
3.8
|
127.4
|
1.0
|
|
H
|
B:CYS1163
|
4.0
|
132.7
|
1.0
|
|
HG
|
B:CYS1166
|
4.0
|
131.6
|
1.0
|
|
SG
|
B:CYS1166
|
4.1
|
131.6
|
1.0
|
|
OG1
|
B:THR1170
|
4.1
|
119.7
|
1.0
|
|
HB
|
B:ILE1165
|
4.1
|
131.7
|
1.0
|
|
C
|
B:CYS1163
|
4.1
|
132.7
|
1.0
|
|
O
|
B:CYS1163
|
4.2
|
132.7
|
1.0
|
|
HA
|
B:CYS1163
|
4.2
|
132.7
|
1.0
|
|
N
|
B:CYS1163
|
4.3
|
132.7
|
1.0
|
|
H
|
B:LEU1168
|
4.4
|
119.2
|
1.0
|
|
H
|
B:ILE1165
|
4.5
|
131.7
|
1.0
|
|
HA
|
B:CYS1166
|
4.5
|
131.6
|
1.0
|
|
H
|
B:CYS1185
|
4.6
|
129.5
|
1.0
|
|
C
|
B:ILE1165
|
4.7
|
131.7
|
1.0
|
|
CA
|
B:CYS1185
|
4.9
|
129.5
|
1.0
|
|
N
|
B:ILE1165
|
4.9
|
131.7
|
1.0
|
|
O
|
B:LEU1168
|
5.0
|
119.2
|
1.0
|
|
CB
|
B:ILE1165
|
5.0
|
131.7
|
1.0
|
|
CA
|
B:CYS1182
|
5.0
|
127.4
|
1.0
|
|
Zinc binding site 4 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 4 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn401
b:191.5
occ:1.00
|
H
|
C:CYS95
|
1.6
|
126.1
|
1.0
|
|
HB3
|
C:CYS92
|
1.9
|
129.7
|
1.0
|
|
O
|
C:CYS92
|
2.1
|
129.7
|
1.0
|
|
N
|
C:CYS95
|
2.2
|
126.1
|
1.0
|
|
SG
|
C:CYS95
|
2.3
|
126.1
|
1.0
|
|
HG2
|
C:LYS94
|
2.3
|
128.0
|
1.0
|
|
C
|
C:CYS92
|
2.4
|
129.7
|
1.0
|
|
CB
|
C:CYS92
|
2.5
|
129.7
|
1.0
|
|
H
|
C:CYS92
|
2.7
|
129.7
|
1.0
|
|
CA
|
C:CYS92
|
2.7
|
129.7
|
1.0
|
|
CB
|
C:CYS95
|
2.8
|
126.1
|
1.0
|
|
HB3
|
C:CYS95
|
2.9
|
126.1
|
1.0
|
|
CA
|
C:CYS95
|
2.9
|
126.1
|
1.0
|
|
H
|
C:LYS94
|
3.0
|
128.0
|
1.0
|
|
N
|
C:CYS92
|
3.0
|
129.7
|
1.0
|
|
N
|
C:LYS94
|
3.1
|
128.0
|
1.0
|
|
CG
|
C:LYS94
|
3.1
|
128.0
|
1.0
|
|
HG3
|
C:LYS94
|
3.1
|
128.0
|
1.0
|
|
C
|
C:LYS94
|
3.1
|
128.0
|
1.0
|
|
H
|
C:SER96
|
3.2
|
117.5
|
1.0
|
|
N
|
C:ASP93
|
3.3
|
126.4
|
1.0
|
|
HB2
|
C:CYS92
|
3.4
|
129.7
|
1.0
|
|
SG
|
C:CYS92
|
3.4
|
129.7
|
1.0
|
|
CA
|
C:LYS94
|
3.4
|
128.0
|
1.0
|
|
C
|
C:ASP93
|
3.6
|
126.4
|
1.0
|
|
SG
|
C:CYS86
|
3.6
|
119.9
|
1.0
|
|
C
|
C:CYS95
|
3.6
|
126.1
|
1.0
|
|
N
|
C:SER96
|
3.6
|
117.5
|
1.0
|
|
HG
|
C:SER96
|
3.6
|
117.5
|
1.0
|
|
HA
|
C:CYS92
|
3.7
|
129.7
|
1.0
|
|
HB2
|
C:CYS95
|
3.8
|
126.1
|
1.0
|
|
HA
|
C:CYS95
|
3.8
|
126.1
|
1.0
|
|
CB
|
C:LYS94
|
3.8
|
128.0
|
1.0
|
|
H
|
C:ASP93
|
3.9
|
126.4
|
1.0
|
|
SG
|
C:CYS88
|
3.9
|
125.2
|
1.0
|
|
HG
|
C:CYS92
|
3.9
|
129.7
|
1.0
|
|
CA
|
C:ASP93
|
4.0
|
126.4
|
1.0
|
|
O
|
C:LYS94
|
4.1
|
128.0
|
1.0
|
|
HG
|
C:CYS86
|
4.2
|
119.9
|
1.0
|
|
HD3
|
C:LYS94
|
4.2
|
128.0
|
1.0
|
|
O
|
C:ASP93
|
4.3
|
126.4
|
1.0
|
|
CD
|
C:LYS94
|
4.3
|
128.0
|
1.0
|
|
C
|
C:HIS91
|
4.3
|
114.8
|
1.0
|
|
HB3
|
C:LYS94
|
4.3
|
128.0
|
1.0
|
|
HA
|
C:LYS94
|
4.4
|
128.0
|
1.0
|
|
HA
|
C:ASP93
|
4.4
|
126.4
|
1.0
|
|
OG
|
C:SER96
|
4.5
|
117.5
|
1.0
|
|
HB3
|
C:CYS88
|
4.5
|
125.2
|
1.0
|
|
HB2
|
C:LYS94
|
4.5
|
128.0
|
1.0
|
|
HB2
|
C:CYS86
|
4.6
|
119.9
|
1.0
|
|
O
|
C:CYS95
|
4.6
|
126.1
|
1.0
|
|
HD2
|
C:LYS94
|
4.6
|
128.0
|
1.0
|
|
CB
|
C:CYS86
|
4.6
|
119.9
|
1.0
|
|
HB3
|
C:SER96
|
4.7
|
117.5
|
1.0
|
|
HB3
|
C:CYS86
|
4.7
|
119.9
|
1.0
|
|
HA
|
C:HIS91
|
4.7
|
114.8
|
1.0
|
|
HG
|
C:CYS88
|
4.8
|
125.2
|
1.0
|
|
CA
|
C:SER96
|
4.8
|
117.5
|
1.0
|
|
CB
|
C:CYS88
|
4.8
|
125.2
|
1.0
|
|
CB
|
C:SER96
|
4.9
|
117.5
|
1.0
|
|
Zinc binding site 5 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 5 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn201
b:232.5
occ:1.00
|
O
|
I:THR31
|
2.0
|
192.9
|
1.0
|
|
C
|
I:THR31
|
2.9
|
192.9
|
1.0
|
|
CA
|
I:CYS32
|
3.2
|
205.4
|
1.0
|
|
CB
|
I:CYS10
|
3.3
|
205.9
|
1.0
|
|
N
|
I:CYS32
|
3.4
|
205.4
|
1.0
|
|
CB
|
I:CYS32
|
3.5
|
205.4
|
1.0
|
|
CB
|
I:CYS7
|
3.8
|
204.9
|
1.0
|
|
CB
|
I:THR31
|
4.2
|
192.9
|
1.0
|
|
CA
|
I:THR31
|
4.2
|
192.9
|
1.0
|
|
N
|
I:CYS10
|
4.2
|
205.9
|
1.0
|
|
CA
|
I:CYS10
|
4.4
|
205.9
|
1.0
|
|
C
|
I:CYS32
|
4.6
|
205.4
|
1.0
|
|
C
|
I:ASP9
|
4.7
|
209.9
|
1.0
|
|
N
|
I:SER33
|
4.9
|
214.5
|
1.0
|
|
Zinc binding site 6 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 6 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn202
b:214.4
occ:1.00
|
OG
|
I:SER105
|
2.0
|
147.7
|
1.0
|
|
SG
|
I:CYS106
|
2.3
|
148.5
|
1.0
|
|
SG
|
I:CYS103
|
2.3
|
147.6
|
1.0
|
|
H
|
I:CYS106
|
2.7
|
148.5
|
1.0
|
|
CB
|
I:CYS78
|
2.7
|
150.7
|
1.0
|
|
HB3
|
I:CYS106
|
3.0
|
148.5
|
1.0
|
|
N
|
I:CYS106
|
3.0
|
148.5
|
1.0
|
|
CB
|
I:CYS106
|
3.1
|
148.5
|
1.0
|
|
CB
|
I:SER105
|
3.3
|
147.7
|
1.0
|
|
C
|
I:SER105
|
3.5
|
147.7
|
1.0
|
|
CA
|
I:CYS106
|
3.6
|
148.5
|
1.0
|
|
HB3
|
I:CYS103
|
3.7
|
147.6
|
1.0
|
|
CB
|
I:CYS103
|
3.7
|
147.6
|
1.0
|
|
HB2
|
I:SER105
|
3.8
|
147.7
|
1.0
|
|
CA
|
I:SER105
|
3.8
|
147.7
|
1.0
|
|
H
|
I:SER105
|
3.9
|
147.7
|
1.0
|
|
HB3
|
I:SER105
|
4.0
|
147.7
|
1.0
|
|
HB2
|
I:CYS106
|
4.0
|
148.5
|
1.0
|
|
N
|
I:SER105
|
4.0
|
147.7
|
1.0
|
|
CA
|
I:CYS78
|
4.2
|
150.7
|
1.0
|
|
HB2
|
I:CYS103
|
4.3
|
147.6
|
1.0
|
|
HA
|
I:CYS106
|
4.4
|
148.5
|
1.0
|
|
O
|
I:CYS103
|
4.4
|
147.6
|
1.0
|
|
O
|
I:SER105
|
4.4
|
147.7
|
1.0
|
|
CB
|
I:CYS75
|
4.4
|
152.7
|
1.0
|
|
C
|
I:CYS106
|
4.5
|
148.5
|
1.0
|
|
H
|
I:SER107
|
4.5
|
148.5
|
1.0
|
|
C
|
I:CYS103
|
4.5
|
147.6
|
1.0
|
|
HB3
|
I:HIS108
|
4.5
|
146.7
|
1.0
|
|
H
|
I:HIS108
|
4.6
|
146.7
|
1.0
|
|
N
|
I:CYS78
|
4.6
|
150.7
|
1.0
|
|
CB
|
I:SER80
|
4.7
|
146.3
|
1.0
|
|
HA
|
I:SER105
|
4.8
|
147.7
|
1.0
|
|
CA
|
I:CYS103
|
4.8
|
147.6
|
1.0
|
|
N
|
I:SER107
|
4.8
|
148.5
|
1.0
|
|
HB2
|
I:HIS108
|
4.8
|
146.7
|
1.0
|
|
C
|
I:LEU104
|
4.9
|
141.7
|
1.0
|
|
Zinc binding site 7 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 7 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn101
b:131.3
occ:1.00
|
C
|
J:CYS45
|
2.2
|
88.2
|
1.0
|
|
SG
|
J:CYS10
|
2.3
|
84.7
|
1.0
|
|
SG
|
J:CYS46
|
2.3
|
90.7
|
1.0
|
|
SG
|
J:CYS45
|
2.3
|
88.2
|
1.0
|
|
O
|
J:CYS45
|
2.3
|
88.2
|
1.0
|
|
N
|
J:CYS46
|
2.3
|
90.7
|
1.0
|
|
HA
|
J:CYS46
|
2.6
|
90.7
|
1.0
|
|
CA
|
J:CYS46
|
2.8
|
90.7
|
1.0
|
|
HB2
|
J:CYS10
|
2.8
|
84.7
|
1.0
|
|
H
|
J:CYS46
|
2.8
|
90.7
|
1.0
|
|
HB2
|
J:CYS45
|
2.9
|
88.2
|
1.0
|
|
CB
|
J:CYS45
|
2.9
|
88.2
|
1.0
|
|
CB
|
J:CYS46
|
3.0
|
90.7
|
1.0
|
|
H
|
J:CYS10
|
3.1
|
84.7
|
1.0
|
|
CA
|
J:CYS45
|
3.1
|
88.2
|
1.0
|
|
CB
|
J:CYS10
|
3.1
|
84.7
|
1.0
|
|
HB3
|
J:CYS7
|
3.1
|
79.0
|
1.0
|
|
OG
|
J:SER9
|
3.6
|
77.7
|
1.0
|
|
HB3
|
J:CYS46
|
3.7
|
90.7
|
1.0
|
|
HB2
|
J:CYS46
|
3.7
|
90.7
|
1.0
|
|
HA
|
J:CYS45
|
3.8
|
88.2
|
1.0
|
|
HE
|
J:ARG43
|
3.8
|
84.7
|
1.0
|
|
N
|
J:CYS10
|
3.8
|
84.7
|
1.0
|
|
HB3
|
J:CYS45
|
3.8
|
88.2
|
1.0
|
|
HB3
|
J:CYS10
|
3.8
|
84.7
|
1.0
|
|
CB
|
J:CYS7
|
3.8
|
79.0
|
1.0
|
|
HH21
|
J:ARG43
|
3.9
|
84.7
|
1.0
|
|
HG
|
J:CYS7
|
3.9
|
79.0
|
1.0
|
|
HB2
|
J:CYS7
|
4.0
|
79.0
|
1.0
|
|
N
|
J:CYS45
|
4.0
|
88.2
|
1.0
|
|
SG
|
J:CYS7
|
4.0
|
79.0
|
1.0
|
|
CA
|
J:CYS10
|
4.1
|
84.7
|
1.0
|
|
H
|
J:CYS45
|
4.2
|
88.2
|
1.0
|
|
C
|
J:CYS46
|
4.3
|
90.7
|
1.0
|
|
HB2
|
J:ARG43
|
4.3
|
84.7
|
1.0
|
|
H
|
J:SER9
|
4.5
|
77.7
|
1.0
|
|
HA
|
J:CYS10
|
4.5
|
84.7
|
1.0
|
|
HH21
|
J:ARG48
|
4.6
|
74.9
|
1.0
|
|
NE
|
J:ARG43
|
4.6
|
84.7
|
1.0
|
|
NH2
|
J:ARG43
|
4.6
|
84.7
|
1.0
|
|
HD11
|
B:ILE824
|
4.7
|
71.9
|
1.0
|
|
HB3
|
J:ARG43
|
4.8
|
84.7
|
1.0
|
|
HH22
|
J:ARG48
|
4.8
|
74.9
|
1.0
|
|
H
|
J:ARG47
|
4.9
|
77.6
|
1.0
|
|
C
|
J:TYR44
|
4.9
|
79.0
|
1.0
|
|
NH2
|
J:ARG48
|
4.9
|
74.9
|
1.0
|
|
CB
|
J:SER9
|
4.9
|
77.7
|
1.0
|
|
C
|
J:SER9
|
5.0
|
77.7
|
1.0
|
|
O
|
J:ARG43
|
5.0
|
84.7
|
1.0
|
|
N
|
J:ARG47
|
5.0
|
77.6
|
1.0
|
|
Zinc binding site 8 out
of 8 in 8tvs
Go back to
Zinc Binding Sites List in 8tvs
Zinc binding site 8 out
of 8 in the Cryo-Em Structure of Backtracked Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Cryo-Em Structure of Backtracked Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Zn101
b:187.8
occ:1.00
|
HB3
|
L:CYS34
|
1.9
|
135.5
|
1.0
|
|
HB2
|
L:CYS34
|
2.1
|
135.5
|
1.0
|
|
SG
|
L:CYS31
|
2.3
|
134.6
|
1.0
|
|
SG
|
L:CYS51
|
2.3
|
127.0
|
1.0
|
|
CB
|
L:CYS34
|
2.3
|
135.5
|
1.0
|
|
O
|
L:ALA32
|
2.5
|
128.0
|
1.0
|
|
N
|
L:CYS34
|
2.6
|
135.5
|
1.0
|
|
O
|
L:CYS31
|
2.6
|
134.6
|
1.0
|
|
H
|
L:CYS34
|
2.8
|
135.5
|
1.0
|
|
C
|
L:GLU33
|
2.8
|
128.2
|
1.0
|
|
CA
|
L:CYS34
|
2.9
|
135.5
|
1.0
|
|
C
|
L:ALA32
|
3.2
|
128.0
|
1.0
|
|
O
|
L:GLU33
|
3.3
|
128.2
|
1.0
|
|
HB2
|
L:GLU33
|
3.3
|
128.2
|
1.0
|
|
C
|
L:CYS31
|
3.3
|
134.6
|
1.0
|
|
HB3
|
L:CYS31
|
3.3
|
134.6
|
1.0
|
|
CB
|
L:CYS31
|
3.4
|
134.6
|
1.0
|
|
CA
|
L:GLU33
|
3.6
|
128.2
|
1.0
|
|
CB
|
L:CYS51
|
3.6
|
127.0
|
1.0
|
|
HB2
|
L:CYS51
|
3.6
|
127.0
|
1.0
|
|
N
|
L:GLU33
|
3.7
|
128.2
|
1.0
|
|
HA
|
L:CYS34
|
3.7
|
135.5
|
1.0
|
|
O
|
L:CYS34
|
3.8
|
135.5
|
1.0
|
|
C
|
L:CYS34
|
3.8
|
135.5
|
1.0
|
|
CB
|
L:GLU33
|
3.8
|
128.2
|
1.0
|
|
HB3
|
L:CYS51
|
3.9
|
127.0
|
1.0
|
|
CA
|
L:CYS31
|
3.9
|
134.6
|
1.0
|
|
SG
|
L:CYS34
|
4.0
|
135.5
|
1.0
|
|
N
|
L:ALA32
|
4.0
|
128.0
|
1.0
|
|
HG
|
L:CYS48
|
4.1
|
130.0
|
1.0
|
|
HB3
|
L:GLU33
|
4.1
|
128.2
|
1.0
|
|
HB2
|
L:CYS31
|
4.2
|
134.6
|
1.0
|
|
CA
|
L:ALA32
|
4.2
|
128.0
|
1.0
|
|
HA
|
L:CYS31
|
4.4
|
134.6
|
1.0
|
|
H
|
L:GLU33
|
4.4
|
128.2
|
1.0
|
|
HA
|
L:GLU33
|
4.5
|
128.2
|
1.0
|
|
HB3
|
L:CYS48
|
4.6
|
130.0
|
1.0
|
|
OG
|
L:SER36
|
4.6
|
137.2
|
1.0
|
|
HA
|
L:ALA32
|
4.6
|
128.0
|
1.0
|
|
HG
|
L:CYS34
|
4.6
|
135.5
|
1.0
|
|
HG
|
L:SER36
|
4.7
|
137.2
|
1.0
|
|
H
|
L:ALA32
|
4.8
|
128.0
|
1.0
|
|
H
|
L:SER36
|
4.8
|
137.2
|
1.0
|
|
CA
|
L:CYS51
|
4.9
|
127.0
|
1.0
|
|
SG
|
L:CYS48
|
5.0
|
130.0
|
1.0
|
|
N
|
L:SER35
|
5.0
|
139.7
|
1.0
|
|
Reference:
R.D.Sarsam,
J.Xu,
I.Lahiri,
W.Gong,
Q.Li,
J.Oh,
Z.Zhou,
P.Hou,
J.Chong,
N.Hao,
S.Li,
D.Wang,
A.E.Leschziner.
ELF1 Promotes RAD26'S Interaction with Lesion-Arrested Pol II For Transcription-Coupled Repair. Proc.Natl.Acad.Sci.Usa V. 121 45121 2024.
ISSN: ESSN 1091-6490
PubMed: 38194460
DOI: 10.1073/PNAS.2314245121
Page generated: Thu Oct 31 11:48:28 2024
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