Zinc in PDB 8tvq: Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
Enzymatic activity of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
All present enzymatic activity of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26:
2.7.7.6;
Other elements in 8tvq:
The structure of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
(pdb code 8tvq). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 8 binding sites of Zinc where determined in the
Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26, PDB code: 8tvq:
Jump to Zinc binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Zinc binding site 1 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 1 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 1 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1801
b:229.2
occ:1.00
|
O
|
A:CYS107
|
1.5
|
251.8
|
1.0
|
|
SG
|
A:CYS167
|
2.0
|
252.8
|
1.0
|
|
SG
|
A:CYS110
|
2.4
|
259.8
|
1.0
|
|
O
|
A:MET108
|
2.5
|
238.1
|
1.0
|
|
HB2
|
A:CYS167
|
2.5
|
252.8
|
1.0
|
|
C
|
A:CYS107
|
2.7
|
251.8
|
1.0
|
|
CB
|
A:CYS167
|
2.8
|
252.8
|
1.0
|
|
HB3
|
A:CYS107
|
3.0
|
251.8
|
1.0
|
|
C
|
A:MET108
|
3.1
|
238.1
|
1.0
|
|
HB3
|
A:MET108
|
3.3
|
238.1
|
1.0
|
|
H
|
A:CYS167
|
3.3
|
252.8
|
1.0
|
|
HB3
|
A:CYS167
|
3.4
|
252.8
|
1.0
|
|
HB2
|
A:CYS110
|
3.5
|
259.8
|
1.0
|
|
N
|
A:MET108
|
3.5
|
238.1
|
1.0
|
|
H
|
A:CYS110
|
3.5
|
259.8
|
1.0
|
|
CB
|
A:CYS110
|
3.6
|
259.8
|
1.0
|
|
SG
|
A:CYS148
|
3.6
|
258.4
|
1.0
|
|
CA
|
A:MET108
|
3.7
|
238.1
|
1.0
|
|
N
|
A:CYS110
|
3.7
|
259.8
|
1.0
|
|
CA
|
A:CYS107
|
3.7
|
251.8
|
1.0
|
|
CB
|
A:CYS107
|
3.8
|
251.8
|
1.0
|
|
HB2
|
A:HIS109
|
3.8
|
251.0
|
1.0
|
|
N
|
A:HIS109
|
3.9
|
251.0
|
1.0
|
|
N
|
A:CYS167
|
3.9
|
252.8
|
1.0
|
|
C
|
A:HIS109
|
3.9
|
251.0
|
1.0
|
|
HA
|
A:CYS107
|
3.9
|
251.8
|
1.0
|
|
CB
|
A:MET108
|
3.9
|
238.1
|
1.0
|
|
CA
|
A:CYS167
|
4.0
|
252.8
|
1.0
|
|
HB2
|
A:CYS107
|
4.1
|
251.8
|
1.0
|
|
HB2
|
A:CYS148
|
4.2
|
258.4
|
1.0
|
|
HB3
|
A:CYS148
|
4.2
|
258.4
|
1.0
|
|
HE21
|
A:GLN171
|
4.2
|
242.2
|
1.0
|
|
CA
|
A:CYS110
|
4.3
|
259.8
|
1.0
|
|
CA
|
A:HIS109
|
4.3
|
251.0
|
1.0
|
|
HG
|
A:CYS148
|
4.3
|
258.4
|
1.0
|
|
CB
|
A:CYS148
|
4.3
|
258.4
|
1.0
|
|
H
|
A:MET108
|
4.3
|
238.1
|
1.0
|
|
HB3
|
A:CYS110
|
4.4
|
259.8
|
1.0
|
|
HA
|
A:CYS167
|
4.4
|
252.8
|
1.0
|
|
O
|
A:HIS109
|
4.5
|
251.0
|
1.0
|
|
CB
|
A:HIS109
|
4.5
|
251.0
|
1.0
|
|
HG2
|
A:MET108
|
4.5
|
238.1
|
1.0
|
|
H
|
A:HIS109
|
4.5
|
251.0
|
1.0
|
|
HA
|
A:MET108
|
4.6
|
238.1
|
1.0
|
|
HB2
|
A:MET108
|
4.6
|
238.1
|
1.0
|
|
OD1
|
A:ASN169
|
4.7
|
258.1
|
1.0
|
|
NE2
|
A:GLN171
|
4.7
|
242.2
|
1.0
|
|
HA
|
A:CYS110
|
4.7
|
259.8
|
1.0
|
|
HE22
|
A:GLN171
|
4.8
|
242.2
|
1.0
|
|
HD2
|
A:HIS109
|
4.8
|
251.0
|
1.0
|
|
CG
|
A:MET108
|
4.8
|
238.1
|
1.0
|
|
H
|
A:GLY168
|
5.0
|
258.2
|
1.0
|
|
Zinc binding site 2 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 2 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 2 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Zn1802
b:169.5
occ:1.00
|
NE2
|
A:HIS80
|
1.1
|
216.2
|
1.0
|
|
CE1
|
A:HIS80
|
1.9
|
216.2
|
1.0
|
|
O
|
A:CYS67
|
2.2
|
243.7
|
1.0
|
|
HE1
|
A:HIS80
|
2.2
|
216.2
|
1.0
|
|
HB3
|
A:CYS67
|
2.3
|
243.7
|
1.0
|
|
CD2
|
A:HIS80
|
2.3
|
216.2
|
1.0
|
|
SG
|
A:CYS77
|
2.6
|
216.3
|
1.0
|
|
HD2
|
A:HIS80
|
2.8
|
216.2
|
1.0
|
|
HB2
|
A:CYS70
|
2.8
|
252.8
|
1.0
|
|
O
|
A:PRO78
|
3.0
|
205.7
|
1.0
|
|
ND1
|
A:HIS80
|
3.0
|
216.2
|
1.0
|
|
C
|
A:CYS67
|
3.0
|
243.7
|
1.0
|
|
CB
|
A:CYS67
|
3.1
|
243.7
|
1.0
|
|
HG
|
A:CYS70
|
3.2
|
252.8
|
1.0
|
|
SG
|
A:CYS70
|
3.2
|
252.8
|
1.0
|
|
CG
|
A:HIS80
|
3.2
|
216.2
|
1.0
|
|
HB2
|
A:CYS67
|
3.4
|
243.7
|
1.0
|
|
CB
|
A:CYS70
|
3.4
|
252.8
|
1.0
|
|
CA
|
A:CYS67
|
3.5
|
243.7
|
1.0
|
|
HB3
|
A:GLN68
|
3.6
|
236.6
|
1.0
|
|
HA
|
A:CYS67
|
3.7
|
243.7
|
1.0
|
|
HB3
|
A:CYS70
|
3.8
|
252.8
|
1.0
|
|
HD1
|
A:HIS80
|
3.8
|
216.2
|
1.0
|
|
N
|
A:GLN68
|
4.1
|
236.6
|
1.0
|
|
C
|
A:PRO78
|
4.2
|
205.7
|
1.0
|
|
HA2
|
A:GLY79
|
4.3
|
204.1
|
1.0
|
|
HB2
|
A:GLN68
|
4.3
|
236.6
|
1.0
|
|
CB
|
A:GLN68
|
4.3
|
236.6
|
1.0
|
|
H
|
A:CYS70
|
4.4
|
252.8
|
1.0
|
|
O
|
A:GLY79
|
4.4
|
204.1
|
1.0
|
|
CB
|
A:CYS77
|
4.4
|
216.3
|
1.0
|
|
C
|
A:GLY79
|
4.5
|
204.1
|
1.0
|
|
SG
|
A:CYS67
|
4.5
|
243.7
|
1.0
|
|
HA2
|
A:GLY59
|
4.6
|
226.4
|
1.0
|
|
CB
|
A:HIS80
|
4.7
|
216.2
|
1.0
|
|
HB3
|
A:CYS77
|
4.7
|
216.3
|
1.0
|
|
CA
|
A:GLN68
|
4.7
|
236.6
|
1.0
|
|
CA
|
A:CYS70
|
4.7
|
252.8
|
1.0
|
|
HG
|
A:CYS67
|
4.7
|
243.7
|
1.0
|
|
H
|
A:GLN68
|
4.8
|
236.6
|
1.0
|
|
CA
|
A:GLY79
|
4.8
|
204.1
|
1.0
|
|
HB2
|
A:CYS77
|
4.8
|
216.3
|
1.0
|
|
O
|
A:GLN68
|
4.9
|
236.6
|
1.0
|
|
HD2
|
A:PRO78
|
4.9
|
205.7
|
1.0
|
|
N
|
A:CYS70
|
4.9
|
252.8
|
1.0
|
|
N
|
A:CYS67
|
4.9
|
243.7
|
1.0
|
|
HB2
|
A:HIS80
|
5.0
|
216.2
|
1.0
|
|
N
|
A:HIS80
|
5.0
|
216.2
|
1.0
|
|
C
|
A:GLN68
|
5.0
|
236.6
|
1.0
|
|
N
|
A:GLY79
|
5.0
|
204.1
|
1.0
|
|
Zinc binding site 3 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 3 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 3 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Zn1301
b:172.8
occ:1.00
|
H
|
B:CYS1166
|
2.0
|
224.2
|
1.0
|
|
SG
|
B:CYS1185
|
2.0
|
236.0
|
1.0
|
|
SG
|
B:CYS1166
|
2.0
|
224.2
|
1.0
|
|
HG
|
B:CYS1182
|
2.3
|
241.7
|
1.0
|
|
SG
|
B:CYS1163
|
2.4
|
226.0
|
1.0
|
|
N
|
B:CYS1166
|
2.5
|
224.2
|
1.0
|
|
HB
|
B:ILE1165
|
2.5
|
238.3
|
1.0
|
|
CB
|
B:CYS1166
|
2.8
|
224.2
|
1.0
|
|
HB3
|
B:CYS1163
|
2.8
|
226.0
|
1.0
|
|
HB3
|
B:CYS1166
|
2.8
|
224.2
|
1.0
|
|
CA
|
B:CYS1166
|
3.1
|
224.2
|
1.0
|
|
CB
|
B:CYS1163
|
3.1
|
226.0
|
1.0
|
|
CB
|
B:CYS1185
|
3.2
|
236.0
|
1.0
|
|
HB2
|
B:CYS1185
|
3.2
|
236.0
|
1.0
|
|
HB3
|
B:CYS1185
|
3.3
|
236.0
|
1.0
|
|
C
|
B:ILE1165
|
3.4
|
238.3
|
1.0
|
|
CB
|
B:ILE1165
|
3.4
|
238.3
|
1.0
|
|
O
|
B:CYS1166
|
3.4
|
224.2
|
1.0
|
|
SG
|
B:CYS1182
|
3.4
|
241.7
|
1.0
|
|
HG22
|
B:ILE1165
|
3.6
|
238.3
|
1.0
|
|
HB2
|
B:CYS1163
|
3.6
|
226.0
|
1.0
|
|
HB2
|
B:CYS1166
|
3.7
|
224.2
|
1.0
|
|
C
|
B:CYS1166
|
3.7
|
224.2
|
1.0
|
|
CA
|
B:ILE1165
|
3.8
|
238.3
|
1.0
|
|
H
|
B:ILE1165
|
3.8
|
238.3
|
1.0
|
|
HA
|
B:CYS1166
|
3.9
|
224.2
|
1.0
|
|
N
|
B:ILE1165
|
4.0
|
238.3
|
1.0
|
|
CG2
|
B:ILE1165
|
4.0
|
238.3
|
1.0
|
|
HB3
|
B:CYS1182
|
4.2
|
241.7
|
1.0
|
|
O
|
B:ILE1165
|
4.3
|
238.3
|
1.0
|
|
O
|
B:CYS1163
|
4.3
|
226.0
|
1.0
|
|
HG21
|
B:ILE1165
|
4.4
|
238.3
|
1.0
|
|
CA
|
B:CYS1163
|
4.4
|
226.0
|
1.0
|
|
CB
|
B:CYS1182
|
4.4
|
241.7
|
1.0
|
|
C
|
B:CYS1163
|
4.4
|
226.0
|
1.0
|
|
CG1
|
B:ILE1165
|
4.5
|
238.3
|
1.0
|
|
HG12
|
B:ILE1165
|
4.5
|
238.3
|
1.0
|
|
CA
|
B:CYS1185
|
4.6
|
236.0
|
1.0
|
|
H
|
B:CYS1185
|
4.6
|
236.0
|
1.0
|
|
HB2
|
B:CYS1182
|
4.6
|
241.7
|
1.0
|
|
HG13
|
B:ILE1165
|
4.7
|
238.3
|
1.0
|
|
HA
|
B:ILE1165
|
4.7
|
238.3
|
1.0
|
|
H
|
B:LEU1168
|
4.7
|
214.8
|
1.0
|
|
HG1
|
B:THR1170
|
4.8
|
210.3
|
1.0
|
|
HB2
|
B:LEU1168
|
4.8
|
214.8
|
1.0
|
|
HG23
|
B:ILE1165
|
4.8
|
238.3
|
1.0
|
|
HA
|
B:CYS1185
|
4.8
|
236.0
|
1.0
|
|
C
|
B:GLY1164
|
4.9
|
222.5
|
1.0
|
|
HA
|
B:CYS1163
|
4.9
|
226.0
|
1.0
|
|
OG1
|
B:THR1170
|
5.0
|
210.3
|
1.0
|
|
N
|
B:CYS1185
|
5.0
|
236.0
|
1.0
|
|
Zinc binding site 4 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 4 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 4 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Zn401
b:134.2
occ:1.00
|
H
|
C:CYS95
|
1.8
|
227.4
|
1.0
|
|
O
|
C:CYS92
|
2.0
|
228.1
|
1.0
|
|
SG
|
C:CYS95
|
2.0
|
227.4
|
1.0
|
|
H
|
C:CYS92
|
2.1
|
228.1
|
1.0
|
|
HG
|
C:CYS88
|
2.4
|
226.8
|
1.0
|
|
N
|
C:CYS95
|
2.5
|
227.4
|
1.0
|
|
SG
|
C:CYS92
|
2.5
|
228.1
|
1.0
|
|
C
|
C:CYS92
|
2.5
|
228.1
|
1.0
|
|
N
|
C:CYS92
|
2.7
|
228.1
|
1.0
|
|
CA
|
C:CYS92
|
2.9
|
228.1
|
1.0
|
|
CB
|
C:CYS95
|
2.9
|
227.4
|
1.0
|
|
CA
|
C:CYS95
|
3.0
|
227.4
|
1.0
|
|
HG
|
C:SER96
|
3.0
|
220.1
|
1.0
|
|
H
|
C:SER96
|
3.1
|
220.1
|
1.0
|
|
CB
|
C:CYS92
|
3.2
|
228.1
|
1.0
|
|
HB3
|
C:CYS95
|
3.2
|
227.4
|
1.0
|
|
N
|
C:SER96
|
3.3
|
220.1
|
1.0
|
|
C
|
C:CYS95
|
3.3
|
227.4
|
1.0
|
|
H
|
C:LYS94
|
3.4
|
225.9
|
1.0
|
|
N
|
C:LYS94
|
3.5
|
225.9
|
1.0
|
|
C
|
C:LYS94
|
3.5
|
225.9
|
1.0
|
|
SG
|
C:CYS88
|
3.5
|
226.8
|
1.0
|
|
HB2
|
C:LYS94
|
3.5
|
225.9
|
1.0
|
|
HB3
|
C:CYS92
|
3.6
|
228.1
|
1.0
|
|
N
|
C:ASP93
|
3.6
|
224.2
|
1.0
|
|
SG
|
C:CYS86
|
3.7
|
223.6
|
1.0
|
|
C
|
C:HIS91
|
3.7
|
204.6
|
1.0
|
|
HB2
|
C:CYS95
|
3.8
|
227.4
|
1.0
|
|
OG
|
C:SER96
|
3.8
|
220.1
|
1.0
|
|
HA
|
C:CYS92
|
3.8
|
228.1
|
1.0
|
|
HA
|
C:HIS91
|
3.8
|
204.6
|
1.0
|
|
C
|
C:ASP93
|
3.9
|
224.2
|
1.0
|
|
HA
|
C:CYS95
|
3.9
|
227.4
|
1.0
|
|
CA
|
C:LYS94
|
3.9
|
225.9
|
1.0
|
|
HB3
|
C:SER96
|
4.0
|
220.1
|
1.0
|
|
HB2
|
C:CYS92
|
4.0
|
228.1
|
1.0
|
|
HG
|
C:CYS86
|
4.2
|
223.6
|
1.0
|
|
CB
|
C:LYS94
|
4.2
|
225.9
|
1.0
|
|
O
|
C:CYS95
|
4.2
|
227.4
|
1.0
|
|
CB
|
C:SER96
|
4.3
|
220.1
|
1.0
|
|
H
|
C:ASP93
|
4.3
|
224.2
|
1.0
|
|
CA
|
C:ASP93
|
4.3
|
224.2
|
1.0
|
|
CA
|
C:HIS91
|
4.3
|
204.6
|
1.0
|
|
CA
|
C:SER96
|
4.3
|
220.1
|
1.0
|
|
HB2
|
C:HIS91
|
4.4
|
204.6
|
1.0
|
|
HB3
|
C:CYS88
|
4.4
|
226.8
|
1.0
|
|
HB3
|
C:CYS86
|
4.5
|
223.6
|
1.0
|
|
O
|
C:ASP93
|
4.5
|
224.2
|
1.0
|
|
O
|
C:LYS94
|
4.5
|
225.9
|
1.0
|
|
HA
|
C:ASP93
|
4.6
|
224.2
|
1.0
|
|
HB2
|
C:CYS86
|
4.6
|
223.6
|
1.0
|
|
CB
|
C:CYS86
|
4.6
|
223.6
|
1.0
|
|
CB
|
C:CYS88
|
4.6
|
226.8
|
1.0
|
|
O
|
C:HIS91
|
4.6
|
204.6
|
1.0
|
|
HB3
|
C:LYS94
|
4.8
|
225.9
|
1.0
|
|
HA
|
C:LYS94
|
4.8
|
225.9
|
1.0
|
|
HB2
|
C:CYS88
|
4.9
|
226.8
|
1.0
|
|
CB
|
C:HIS91
|
4.9
|
204.6
|
1.0
|
|
O
|
C:SER96
|
5.0
|
220.1
|
1.0
|
|
Zinc binding site 5 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 5 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 5 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn201
b:357.1
occ:1.00
|
O
|
I:THR31
|
2.2
|
263.9
|
1.0
|
|
C
|
I:THR31
|
3.3
|
263.9
|
1.0
|
|
CA
|
I:CYS32
|
3.4
|
280.4
|
1.0
|
|
CB
|
I:CYS10
|
3.5
|
275.4
|
1.0
|
|
N
|
I:CYS32
|
3.7
|
280.4
|
1.0
|
|
CB
|
I:CYS32
|
4.0
|
280.4
|
1.0
|
|
N
|
I:CYS10
|
4.1
|
275.4
|
1.0
|
|
CB
|
I:CYS7
|
4.3
|
278.1
|
1.0
|
|
C
|
I:ASP9
|
4.3
|
275.6
|
1.0
|
|
CB
|
I:ASP9
|
4.4
|
275.6
|
1.0
|
|
CA
|
I:CYS10
|
4.4
|
275.4
|
1.0
|
|
C
|
I:CYS32
|
4.5
|
280.4
|
1.0
|
|
N
|
I:SER33
|
4.5
|
269.8
|
1.0
|
|
CA
|
I:THR31
|
4.6
|
263.9
|
1.0
|
|
CB
|
I:THR31
|
4.6
|
263.9
|
1.0
|
|
O
|
I:ASP9
|
4.7
|
275.6
|
1.0
|
|
CA
|
I:ASP9
|
4.8
|
275.6
|
1.0
|
|
N
|
I:ASP9
|
4.8
|
275.6
|
1.0
|
|
Zinc binding site 6 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 6 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 6 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:Zn202
b:316.9
occ:1.00
|
OG
|
I:SER105
|
1.9
|
298.1
|
1.0
|
|
H
|
I:CYS106
|
2.0
|
306.2
|
1.0
|
|
SG
|
I:CYS106
|
2.2
|
306.2
|
1.0
|
|
N
|
I:CYS106
|
2.2
|
306.2
|
1.0
|
|
SG
|
I:CYS103
|
2.5
|
285.0
|
1.0
|
|
HB3
|
I:CYS106
|
2.5
|
306.2
|
1.0
|
|
CB
|
I:CYS106
|
2.6
|
306.2
|
1.0
|
|
C
|
I:SER105
|
2.8
|
298.1
|
1.0
|
|
CA
|
I:CYS106
|
2.9
|
306.2
|
1.0
|
|
CB
|
I:SER105
|
3.0
|
298.1
|
1.0
|
|
CA
|
I:SER105
|
3.2
|
298.1
|
1.0
|
|
HB2
|
I:CYS78
|
3.2
|
285.2
|
1.0
|
|
HB2
|
I:SER105
|
3.4
|
298.1
|
1.0
|
|
H
|
I:SER105
|
3.4
|
298.1
|
1.0
|
|
SG
|
I:CYS78
|
3.4
|
285.2
|
1.0
|
|
N
|
I:SER105
|
3.5
|
298.1
|
1.0
|
|
HB3
|
I:CYS103
|
3.5
|
285.0
|
1.0
|
|
HB2
|
I:CYS106
|
3.6
|
306.2
|
1.0
|
|
O
|
I:SER105
|
3.6
|
298.1
|
1.0
|
|
HA
|
I:CYS106
|
3.6
|
306.2
|
1.0
|
|
CB
|
I:CYS103
|
3.7
|
285.0
|
1.0
|
|
CB
|
I:CYS78
|
3.7
|
285.2
|
1.0
|
|
HB3
|
I:SER105
|
3.7
|
298.1
|
1.0
|
|
HG
|
I:CYS78
|
3.7
|
285.2
|
1.0
|
|
HG
|
I:CYS75
|
3.8
|
295.5
|
1.0
|
|
O
|
I:CYS103
|
3.9
|
285.0
|
1.0
|
|
HB3
|
I:CYS78
|
3.9
|
285.2
|
1.0
|
|
C
|
I:CYS106
|
3.9
|
306.2
|
1.0
|
|
H
|
I:SER107
|
3.9
|
288.1
|
1.0
|
|
HB3
|
I:SER80
|
4.1
|
272.0
|
1.0
|
|
HA
|
I:SER105
|
4.1
|
298.1
|
1.0
|
|
C
|
I:CYS103
|
4.2
|
285.0
|
1.0
|
|
N
|
I:SER107
|
4.2
|
288.1
|
1.0
|
|
C
|
I:LEU104
|
4.3
|
268.2
|
1.0
|
|
H
|
I:HIS108
|
4.3
|
273.1
|
1.0
|
|
HB2
|
I:CYS103
|
4.4
|
285.0
|
1.0
|
|
CA
|
I:CYS103
|
4.6
|
285.0
|
1.0
|
|
HB3
|
I:HIS108
|
4.6
|
273.1
|
1.0
|
|
HB2
|
I:CYS75
|
4.6
|
295.5
|
1.0
|
|
N
|
I:LEU104
|
4.7
|
268.2
|
1.0
|
|
HB2
|
I:HIS108
|
4.7
|
273.1
|
1.0
|
|
O
|
I:LEU104
|
4.8
|
268.2
|
1.0
|
|
SG
|
I:CYS75
|
4.8
|
295.5
|
1.0
|
|
O
|
I:CYS106
|
4.9
|
306.2
|
1.0
|
|
CB
|
I:SER80
|
4.9
|
272.0
|
1.0
|
|
HB3
|
I:CYS75
|
4.9
|
295.5
|
1.0
|
|
H
|
I:CYS78
|
4.9
|
285.2
|
1.0
|
|
HB2
|
I:SER80
|
5.0
|
272.0
|
1.0
|
|
HG
|
I:SER80
|
5.0
|
272.0
|
1.0
|
|
HE3
|
I:LYS77
|
5.0
|
283.9
|
1.0
|
|
Zinc binding site 7 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 7 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 7 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
J:Zn101
b:102.2
occ:1.00
|
SG
|
J:CYS45
|
1.9
|
169.6
|
1.0
|
|
SG
|
J:CYS7
|
2.2
|
175.5
|
1.0
|
|
HB2
|
J:SER9
|
2.4
|
161.8
|
1.0
|
|
HB2
|
J:CYS45
|
2.6
|
169.6
|
1.0
|
|
C
|
J:CYS45
|
2.7
|
169.6
|
1.0
|
|
N
|
J:CYS46
|
2.7
|
177.9
|
1.0
|
|
H
|
J:CYS10
|
2.7
|
176.3
|
1.0
|
|
CB
|
J:CYS45
|
2.7
|
169.6
|
1.0
|
|
H
|
J:CYS46
|
2.9
|
177.9
|
1.0
|
|
SG
|
J:CYS46
|
3.0
|
177.9
|
1.0
|
|
O
|
J:CYS45
|
3.1
|
169.6
|
1.0
|
|
HA
|
J:CYS46
|
3.1
|
177.9
|
1.0
|
|
SG
|
J:CYS10
|
3.2
|
176.3
|
1.0
|
|
CA
|
J:CYS45
|
3.3
|
169.6
|
1.0
|
|
CA
|
J:CYS46
|
3.3
|
177.9
|
1.0
|
|
CB
|
J:SER9
|
3.4
|
161.8
|
1.0
|
|
HB2
|
J:CYS10
|
3.4
|
176.3
|
1.0
|
|
N
|
J:CYS10
|
3.4
|
176.3
|
1.0
|
|
HB3
|
J:CYS45
|
3.6
|
169.6
|
1.0
|
|
CB
|
J:CYS10
|
3.7
|
176.3
|
1.0
|
|
CB
|
J:CYS46
|
3.8
|
177.9
|
1.0
|
|
HB3
|
J:SER9
|
3.8
|
161.8
|
1.0
|
|
CB
|
J:CYS7
|
3.8
|
175.5
|
1.0
|
|
H
|
J:SER9
|
3.8
|
161.8
|
1.0
|
|
HE
|
J:ARG43
|
3.9
|
176.3
|
1.0
|
|
HG
|
J:SER9
|
3.9
|
161.8
|
1.0
|
|
HA
|
J:CYS45
|
4.0
|
169.6
|
1.0
|
|
HB2
|
J:CYS7
|
4.0
|
175.5
|
1.0
|
|
OG
|
J:SER9
|
4.0
|
161.8
|
1.0
|
|
HB3
|
J:CYS7
|
4.1
|
175.5
|
1.0
|
|
HB2
|
J:ARG43
|
4.2
|
176.3
|
1.0
|
|
CA
|
J:CYS10
|
4.2
|
176.3
|
1.0
|
|
CA
|
J:SER9
|
4.2
|
161.8
|
1.0
|
|
N
|
J:CYS45
|
4.2
|
169.6
|
1.0
|
|
C
|
J:SER9
|
4.3
|
161.8
|
1.0
|
|
HB2
|
J:CYS46
|
4.3
|
177.9
|
1.0
|
|
N
|
J:SER9
|
4.4
|
161.8
|
1.0
|
|
H
|
J:CYS45
|
4.4
|
169.6
|
1.0
|
|
HB3
|
J:CYS46
|
4.4
|
177.9
|
1.0
|
|
HB3
|
J:ARG43
|
4.5
|
176.3
|
1.0
|
|
HB3
|
J:CYS10
|
4.6
|
176.3
|
1.0
|
|
HA
|
J:CYS10
|
4.7
|
176.3
|
1.0
|
|
O
|
J:ARG43
|
4.7
|
176.3
|
1.0
|
|
HH21
|
J:ARG43
|
4.7
|
176.3
|
1.0
|
|
NE
|
J:ARG43
|
4.8
|
176.3
|
1.0
|
|
C
|
J:CYS46
|
4.8
|
177.9
|
1.0
|
|
CB
|
J:ARG43
|
4.8
|
176.3
|
1.0
|
|
HH21
|
J:ARG48
|
4.9
|
170.9
|
1.0
|
|
Zinc binding site 8 out
of 8 in 8tvq
Go back to
Zinc Binding Sites List in 8tvq
Zinc binding site 8 out
of 8 in the Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26
 Mono view
 Stereo pair view
|
|
A full contact list of Zinc with other atoms in the Zn binding
site number 8 of Cryo-Em Structure of Cpd Stalled 10-Subunit Pol II in Complex with RAD26 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
L:Zn101
b:255.8
occ:1.00
|
SG
|
L:CYS31
|
1.8
|
251.5
|
1.0
|
|
O
|
L:ALA32
|
2.1
|
245.3
|
1.0
|
|
HB2
|
L:CYS34
|
2.4
|
269.3
|
1.0
|
|
SG
|
L:CYS51
|
2.5
|
256.3
|
1.0
|
|
SG
|
L:CYS34
|
2.6
|
269.3
|
1.0
|
|
H
|
L:CYS34
|
2.6
|
269.3
|
1.0
|
|
N
|
L:CYS34
|
2.7
|
269.3
|
1.0
|
|
CB
|
L:CYS34
|
2.8
|
269.3
|
1.0
|
|
O
|
L:CYS31
|
2.8
|
251.5
|
1.0
|
|
C
|
L:ALA32
|
2.9
|
245.3
|
1.0
|
|
HG
|
L:CYS48
|
3.0
|
249.6
|
1.0
|
|
C
|
L:CYS31
|
3.1
|
251.5
|
1.0
|
|
HB2
|
L:GLU33
|
3.1
|
260.8
|
1.0
|
|
CB
|
L:CYS31
|
3.2
|
251.5
|
1.0
|
|
CA
|
L:CYS34
|
3.3
|
269.3
|
1.0
|
|
C
|
L:GLU33
|
3.3
|
260.8
|
1.0
|
|
HB3
|
L:CYS31
|
3.4
|
251.5
|
1.0
|
|
N
|
L:GLU33
|
3.6
|
260.8
|
1.0
|
|
CA
|
L:CYS31
|
3.7
|
251.5
|
1.0
|
|
HB3
|
L:CYS34
|
3.7
|
269.3
|
1.0
|
|
N
|
L:ALA32
|
3.7
|
245.3
|
1.0
|
|
CA
|
L:GLU33
|
3.7
|
260.8
|
1.0
|
|
CB
|
L:GLU33
|
3.9
|
260.8
|
1.0
|
|
CA
|
L:ALA32
|
3.9
|
245.3
|
1.0
|
|
HA
|
L:CYS31
|
3.9
|
251.5
|
1.0
|
|
HB2
|
L:CYS31
|
3.9
|
251.5
|
1.0
|
|
SG
|
L:CYS48
|
4.0
|
249.6
|
1.0
|
|
HB2
|
L:CYS51
|
4.0
|
256.3
|
1.0
|
|
O
|
L:GLU33
|
4.0
|
260.8
|
1.0
|
|
CB
|
L:CYS51
|
4.0
|
256.3
|
1.0
|
|
C
|
L:CYS34
|
4.1
|
269.3
|
1.0
|
|
HA
|
L:CYS34
|
4.1
|
269.3
|
1.0
|
|
O
|
L:CYS34
|
4.1
|
269.3
|
1.0
|
|
HB2
|
L:ASP50
|
4.2
|
259.5
|
1.0
|
|
H
|
L:ALA32
|
4.3
|
245.3
|
1.0
|
|
H
|
L:GLU33
|
4.4
|
260.8
|
1.0
|
|
HG2
|
L:GLU33
|
4.4
|
260.8
|
1.0
|
|
HA
|
L:ALA32
|
4.5
|
245.3
|
1.0
|
|
OG
|
L:SER36
|
4.5
|
259.2
|
1.0
|
|
HB3
|
L:CYS51
|
4.5
|
256.3
|
1.0
|
|
HB3
|
L:GLU33
|
4.5
|
260.8
|
1.0
|
|
HG
|
L:SER36
|
4.6
|
259.2
|
1.0
|
|
HA
|
L:GLU33
|
4.7
|
260.8
|
1.0
|
|
CG
|
L:GLU33
|
4.8
|
260.8
|
1.0
|
|
H
|
L:SER36
|
4.8
|
259.2
|
1.0
|
|
HB3
|
L:ALA32
|
4.9
|
245.3
|
1.0
|
|
H
|
L:CYS51
|
5.0
|
256.3
|
1.0
|
|
N
|
L:CYS51
|
5.0
|
256.3
|
1.0
|
|
N
|
L:CYS31
|
5.0
|
251.5
|
1.0
|
|
Reference:
R.D.Sarsam,
J.Xu,
I.Lahiri,
W.Gong,
Q.Li,
J.Oh,
Z.Zhou,
P.Hou,
J.Chong,
N.Hao,
S.Li,
D.Wang,
A.E.Leschziner.
ELF1 Promotes RAD26'S Interaction with Lesion-Arrested Pol II For Transcription-Coupled Repair. Proc.Natl.Acad.Sci.Usa V. 121 45121 2024.
ISSN: ESSN 1091-6490
PubMed: 38194460
DOI: 10.1073/PNAS.2314245121
Page generated: Thu Oct 31 11:48:29 2024
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