Zinc in PDB 8rgp: Closed Complex I From Murine Brain

All present enzymatic activity of Closed Complex I From Murine Brain:
7.1.1.2;

The structure of Closed Complex I From Murine Brain also contains other interesting chemical elements:

Potassium	(K)	1 atom
Magnesium	(Mg)	1 atom
Iron	(Fe)	28 atoms

The binding sites of Zinc atom in the Closed Complex I From Murine Brain (pdb code 8rgp). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Closed Complex I From Murine Brain, PDB code: 8rgp:

Zinc binding site 1 out of 1 in the Closed Complex I From Murine Brain


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Closed Complex I From Murine Brain within 5.0Å range: probe atom residue distance (Å) B Occ 7:Zn201 b:67.6 occ:1.00 NE2 7:HIS68 2.0 68.0 1.0 SG 7:CYS84 2.3 102.8 1.0 SG 7:CYS87 2.3 82.0 1.0 SG 7:CYS59 2.3 89.6 1.0 CE1 7:HIS68 2.9 66.5 1.0 CD2 7:HIS68 3.0 56.8 1.0 O 7:ASP60 3.2 89.9 1.0 CB 7:CYS84 3.3 85.5 1.0 CB 7:CYS87 3.3 68.0 1.0 CB 7:CYS59 3.3 68.4 1.0 N 7:CYS87 3.8 67.9 1.0 C 7:ASP60 4.0 87.6 1.0 ND1 7:HIS68 4.0 56.1 1.0 CG 7:HIS68 4.1 53.7 1.0 CA 7:CYS87 4.1 60.2 1.0 C 7:CYS59 4.3 75.0 1.0 CA 7:CYS59 4.4 69.7 1.0 N 7:ASP60 4.4 85.9 1.0 O 7:CYS59 4.6 75.3 1.0 CA 7:ASP60 4.7 79.8 1.0 CA 7:CYS84 4.7 79.2 1.0 CB 7:TYR86 4.7 69.9 1.0 N 7:GLY61 4.8 97.3 1.0 C 7:TYR86 4.9 63.2 1.0 CG2 7:VAL71 4.9 72.1 1.0 C 7:CYS87 4.9 69.6 1.0 CA 7:GLY61 5.0 98.6 1.0

I.Vercellino, L.A.Sazanov. SCAF1 Drives the Compositional Diversity of Mammalian Respirasomes. Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
PubMed: 38575788
DOI: 10.1038/S41594-024-01255-0