Zinc in PDB 8qu5: Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2

All present enzymatic activity of Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2:
3.1.1.29;

The structure of Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2 also contains other interesting chemical elements:

Magnesium

(Mg)

48 atoms

The binding sites of Zinc atom in the Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2 (pdb code 8qu5). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2, PDB code: 8qu5:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2 within 5.0Å range: probe atom residue distance (Å) B Occ 0:Zn200 b:41.7 occ:1.00 SG 0:CYS113 2.3 44.2 1.0 SG 0:CYS126 2.3 40.5 1.0 SG 0:CYS110 2.3 45.3 1.0 SG 0:CYS123 2.3 36.1 1.0 CB 0:CYS123 2.9 32.8 1.0 CB 0:CYS126 3.2 39.9 1.0 CB 0:CYS110 3.3 45.9 1.0 CB 0:CYS113 3.5 45.6 1.0 N 0:CYS126 3.8 38.5 1.0 CA 0:CYS126 4.1 39.2 1.0 N 0:CYS113 4.2 47.2 1.0 CA 0:CYS123 4.3 32.0 1.0 CA 0:CYS113 4.5 44.9 1.0 CB 0:TYR125 4.6 39.2 1.0 CA 0:CYS110 4.7 45.4 1.0 CB 0:GLU112 4.8 66.6 1.0 C 0:TYR125 4.9 37.4 1.0 C 0:CYS123 4.9 32.1 1.0 OE1 0:GLU112 4.9 88.0 1.0 CD2 0:TYR125 5.0 47.1 1.0

Zinc binding site 2 out of 2 in the Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Mt-Lsu Assembly Intermediate in GTPBP8 Knock-Out Cells, State 2 within 5.0Å range: probe atom residue distance (Å) B Occ r:Zn301 b:78.3 occ:1.00 SG r:CYS108 2.3 73.9 1.0 SG I:CYS64 2.3 104.4 1.0 SG r:CYS70 2.4 73.0 1.0 CB r:CYS73 2.7 73.9 1.0 SG r:CYS73 3.5 86.6 1.0 CB I:CYS64 3.6 107.4 1.0 CA r:CYS73 3.8 71.0 1.0 CB r:CYS70 3.9 68.5 1.0 CB r:CYS108 3.9 67.7 1.0 N r:CYS70 4.1 75.8 1.0 N r:CYS73 4.1 68.7 1.0 CE r:LYS78 4.1 110.2 1.0 CA I:CYS64 4.4 110.3 1.0 CA r:CYS70 4.5 69.0 1.0 CG r:LYS78 4.6 96.8 1.0 CD r:LYS78 4.6 106.3 1.0 CG r:GLU111 4.9 62.4 1.0 CB r:GLN69 5.0 92.0 1.0

M.Cipullo, G.Valentin Gese, S.Gopalakrishna, A.Krueger, V.Lobo, M.A.Pirozhkova, J.Marks, P.Palenkova, D.Shiriaev, Y.Liu, J.Misic, Y.Cai, M.Nguyen, A.Abdelbagi, X.Li, M.Minczuk, M.Hafner, D.Benhalevy, A.A.Sarshad, I.Attanasov, B.M.Hallberg, J.Rorbach. GTPBP8 Plays A Role in Mitoribosome Formation in Human Mitochondria Nat Commun 2024.
ISSN: ESSN 2041-1723