Zinc in PDB 8qbn: Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5

The binding sites of Zinc atom in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5 (pdb code 8qbn). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5, PDB code: 8qbn:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5 within 5.0Å range: probe atom residue distance (Å) B Occ 7:Zn701 b:74.8 occ:1.00 ND1 7:HIS303 2.0 52.0 1.0 NE2 7:HIS320 2.3 54.1 1.0 SG 7:CYS322 2.3 55.2 1.0 SG 7:CYS300 2.3 51.2 1.0 CE1 7:HIS303 2.7 52.0 1.0 CE1 7:HIS320 3.1 54.1 1.0 CG 7:HIS303 3.1 52.0 1.0 CB 7:CYS300 3.2 51.2 1.0 CB 7:CYS322 3.3 55.2 1.0 CD2 7:HIS320 3.4 54.1 1.0 CB 7:HIS303 3.7 52.0 1.0 N 7:CYS322 3.7 55.2 1.0 NE2 7:HIS303 3.8 52.0 1.0 CD2 7:HIS303 4.0 52.0 1.0 CA 7:CYS322 4.1 55.2 1.0 ND1 7:HIS320 4.3 54.1 1.0 CA 7:HIS303 4.3 52.0 1.0 CG 7:HIS320 4.4 54.1 1.0 C 7:VAL321 4.6 56.0 1.0 CA 7:CYS300 4.6 51.2 1.0

Zinc binding site 2 out of 3 in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5 within 5.0Å range: probe atom residue distance (Å) B Occ W:Zn701 b:60.0 occ:1.00 ND1 W:HIS303 2.0 43.0 1.0 NE2 W:HIS320 2.3 50.0 1.0 SG W:CYS300 2.3 44.9 1.0 SG W:CYS322 2.3 49.1 1.0 CE1 W:HIS303 2.7 43.0 1.0 CG W:HIS303 3.2 43.0 1.0 CD2 W:HIS320 3.2 50.0 1.0 CE1 W:HIS320 3.3 50.0 1.0 CB W:CYS322 3.5 49.1 1.0 CB W:CYS300 3.5 44.9 1.0 CA W:HIS303 3.5 43.0 1.0 CB W:HIS303 3.8 43.0 1.0 N W:ASN304 3.8 44.0 1.0 N W:CYS322 3.9 49.1 1.0 NE2 W:HIS303 3.9 43.0 1.0 CA W:CYS322 4.1 49.1 1.0 CD2 W:HIS303 4.1 43.0 1.0 C W:HIS303 4.3 43.0 1.0 CG W:HIS320 4.4 50.0 1.0 ND1 W:HIS320 4.4 50.0 1.0 N W:HIS303 4.6 43.0 1.0 C W:VAL321 4.7 47.5 1.0 O W:ASN304 4.7 44.0 1.0 CA W:CYS300 4.9 44.9 1.0 CA W:ASN304 5.0 44.0 1.0

Zinc binding site 3 out of 3 in the Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Structure of the Non-Canonical Ctlh E3 Substrate Receptor WDR26 Bound to YPEL5 within 5.0Å range: probe atom residue distance (Å) B Occ Y:Zn501 b:54.8 occ:1.00 SG Y:CYS17 2.3 37.8 1.0 SG Y:CYS20 2.3 39.9 1.0 SG Y:CYS73 2.3 32.2 1.0 SG Y:CYS76 2.3 36.2 1.0 CB Y:CYS73 3.0 32.2 1.0 CB Y:CYS17 3.2 37.8 1.0 CB Y:CYS76 3.4 36.2 1.0 CB Y:CYS20 3.9 39.9 1.0 N Y:CYS76 4.0 36.2 1.0 N Y:CYS20 4.1 39.9 1.0 CA Y:CYS76 4.3 36.2 1.0 OG1 Y:THR22 4.3 36.6 1.0 CA Y:CYS73 4.5 32.2 1.0 CA Y:CYS20 4.6 39.9 1.0 CB Y:ASN19 4.6 39.6 1.0 OG Y:SER78 4.6 34.0 1.0 CA Y:CYS17 4.7 37.8 1.0 CB Y:ASN75 4.9 32.9 1.0 C Y:ASN75 4.9 32.9 1.0

K.V.Gottemukkala, J.Chrustowicz, D.Sherpa, S.Sepic, T.Vu, O.Karayel, A.Gross, K.Schorpp, S.Von Gronau, K.Hadian, P.J.Murray, M.Mann, B.A.Schulman, A.Alpi. Non-Canonical Substrate Targeting By the Supramolecular Ctlh E3 Ligase Reveals An WDR26-YPEL5 Regulatory Module To Be Published.