Zinc in PDB 9daz: Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd

All present enzymatic activity of Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd:
3.4.11.2;

The binding sites of Zinc atom in the Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd (pdb code 9daz). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd, PDB code: 9daz:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1302 b:56.4 occ:1.00 OE1 A:GLU410 2.3 22.0 1.0 NE2 A:HIS391 2.3 18.0 1.0 NE2 A:HIS387 2.3 17.8 1.0 CD2 A:HIS391 3.1 17.1 1.0 CD2 A:HIS387 3.2 17.7 1.0 CE1 A:HIS387 3.3 16.4 1.0 CE1 A:HIS391 3.4 15.0 1.0 CD A:GLU410 3.4 19.3 1.0 OE2 A:GLU410 3.9 24.8 1.0 OE1 A:GLU354 4.1 30.6 1.0 CG A:HIS391 4.3 15.2 1.0 ND1 A:HIS387 4.3 14.9 1.0 CG A:HIS387 4.3 15.7 1.0 CD A:GLU354 4.4 28.5 1.0 OE2 A:GLU388 4.4 26.2 1.0 CE2 A:TYR476 4.4 20.6 1.0 ND1 A:HIS391 4.4 13.9 1.0 OE2 A:GLU354 4.5 29.5 1.0 CB A:ALA413 4.5 10.8 1.0 CG A:GLU410 4.6 16.1 1.0 CA A:GLU410 4.6 13.9 1.0 CB A:GLU410 4.7 14.4 1.0 OE1 A:GLU388 5.0 26.9 1.0

Zinc binding site 2 out of 2 in the Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Molecular Basis of Pathogenicity of the Recently Emerged Fcov-23 Coronavirus. Complex of Fapn with Fcov-23 Rbd within 5.0Å range: probe atom residue distance (Å) B Occ C:Zn1302 b:56.4 occ:1.00 OE1 C:GLU410 2.3 22.0 1.0 NE2 C:HIS391 2.3 18.0 1.0 NE2 C:HIS387 2.3 17.8 1.0 CD2 C:HIS391 3.1 17.1 1.0 CD2 C:HIS387 3.2 17.7 1.0 CE1 C:HIS387 3.3 16.4 1.0 CE1 C:HIS391 3.4 15.0 1.0 CD C:GLU410 3.4 19.3 1.0 OE2 C:GLU410 3.9 24.8 1.0 OE1 C:GLU354 4.1 30.6 1.0 CG C:HIS391 4.3 15.2 1.0 ND1 C:HIS387 4.3 14.9 1.0 CG C:HIS387 4.3 15.7 1.0 CD C:GLU354 4.4 28.5 1.0 OE2 C:GLU388 4.4 26.2 1.0 CE2 C:TYR476 4.4 20.6 1.0 ND1 C:HIS391 4.4 13.9 1.0 OE2 C:GLU354 4.5 29.5 1.0 CB C:ALA413 4.5 10.8 1.0 CG C:GLU410 4.6 16.1 1.0 CA C:GLU410 4.6 13.9 1.0 CB C:GLU410 4.7 14.4 1.0 OE1 C:GLU388 5.0 26.9 1.0

M.A.Tortorci, A.Choi, C.A.Gibson, J.Lee, J.T.Brown, C.Stewart, A.Joshi, S.Harari, I.Willoughby, C.Treichel, E.M.Leaf, J.D.Bloom, N.P.King, C.Tait-Burkard, G.R.Whittaker, D.Veesler. Loss of Fcov-23 Spike Domain 0 Enhances Fusogenicity and Entry Kinetics Nature 2025.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-025-09155-Z