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Zinc in PDB 8q5p: Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1Enzymatic activity of Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1
All present enzymatic activity of Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1:
2.1.1.43; 2.7.10.2; 2.7.11.1; Protein crystallography data
The structure of Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1, PDB code: 8q5p
was solved by
A.Mechaly,
L.Le Coadou,
J.M.Dupret,
A.Haouz,
F.Rodrigues Lima,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Zinc Binding Sites:
The binding sites of Zinc atom in the Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1
(pdb code 8q5p). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1, PDB code: 8q5p: Jump to Zinc binding site number: 1; 2; 3; Zinc binding site 1 out of 3 in 8q5pGo back to![]() ![]()
Zinc binding site 1 out
of 3 in the Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1
![]() Mono view ![]() Stereo pair view
Zinc binding site 2 out of 3 in 8q5pGo back to![]() ![]()
Zinc binding site 2 out
of 3 in the Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1
![]() Mono view ![]() Stereo pair view
Zinc binding site 3 out of 3 in 8q5pGo back to![]() ![]()
Zinc binding site 3 out
of 3 in the Structure of the Lysine Methyltransferase SETD2 in Complex with A Peptide Derived From Human Tyrosine Kinase ACK1
![]() Mono view ![]() Stereo pair view
Reference:
L.Le Coadou,
J.Berthelet,
A.E.Mechaly,
C.Michail,
L.C.Bui,
J.Dairou,
A.Haouz,
J.M.Dupret,
F.Rodrigues Lima.
Structural and Enzymatic Evidence For the Methylation of the ACK1 Tyrosine Kinase By the Histone Lysine Methyltransferase SETD2. Biochem.Biophys.Res.Commun. V. 695 49400 2024.
Page generated: Thu Oct 31 09:57:08 2024
ISSN: ESSN 1090-2104 PubMed: 38160530 DOI: 10.1016/J.BBRC.2023.149400 |
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