Zinc in PDB 8q0q: Outward-Facing, Slack Proteoliposome Complex I at 3.6 A. Initially Purified in Ddm

All present enzymatic activity of Outward-Facing, Slack Proteoliposome Complex I at 3.6 A. Initially Purified in Ddm:
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Outward-Facing, Slack Proteoliposome Complex I at 3.6 A. Initially Purified in Ddm also contains other interesting chemical elements:

Magnesium	(Mg)	1 atom
Iron	(Fe)	28 atoms
Potassium	(K)	1 atom

The binding sites of Zinc atom in the Outward-Facing, Slack Proteoliposome Complex I at 3.6 A. Initially Purified in Ddm (pdb code 8q0q). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Outward-Facing, Slack Proteoliposome Complex I at 3.6 A. Initially Purified in Ddm, PDB code: 8q0q:

Zinc binding site 1 out of 1 in the Outward-Facing, Slack Proteoliposome Complex I at 3.6 A. Initially Purified in Ddm


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Outward-Facing, Slack Proteoliposome Complex I at 3.6 A. Initially Purified in Ddm within 5.0Å range: probe atom residue distance (Å) B Occ R:Zn201 b:67.1 occ:1.00 NE2 R:HIS68 2.0 33.9 1.0 SG R:CYS87 2.1 36.1 1.0 SG R:CYS84 2.2 39.6 1.0 SG R:CYS59 2.4 36.9 1.0 CE1 R:HIS68 2.5 33.9 1.0 CB R:CYS84 3.2 39.6 1.0 CB R:CYS87 3.2 36.1 1.0 CD2 R:HIS68 3.2 33.9 1.0 CB R:CYS59 3.5 36.9 1.0 N R:GLY61 3.6 28.2 1.0 ND1 R:HIS68 3.7 33.9 1.0 N R:CYS87 3.9 36.1 1.0 CG R:HIS68 4.0 33.9 1.0 C R:CYS59 4.1 36.9 1.0 CA R:CYS87 4.1 36.1 1.0 CA R:GLY61 4.2 28.2 1.0 O R:CYS59 4.3 36.9 1.0 N R:ASP60 4.3 34.2 1.0 CA R:CYS59 4.5 36.9 1.0 C R:ASP60 4.5 34.2 1.0 CA R:ASP60 4.6 34.2 1.0 CA R:CYS84 4.6 39.6 1.0 C R:CYS87 4.9 36.1 1.0 N R:GLY88 4.9 39.4 1.0

D.N.Grba, J.J.Wright, W.Fisher, Z.Yin, J.Hirst. Molecular Mechanism of the Ischemia-Induced Regulatory Switch in Mammalian Complex I Science 2024.
ISSN: ESSN 1095-9203
DOI: 10.1126/SCIENCE.ADO2075