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Zinc in PDB 8ihz: Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) GlycineEnzymatic activity of Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) Glycine
All present enzymatic activity of Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) Glycine:
1.14.11.30; Protein crystallography data
The structure of Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) Glycine, PDB code: 8ihz
was solved by
Y.Nakashima,
T.Corner,
X.Zhang,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 8ihz:
The structure of Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) Glycine also contains other interesting chemical elements:
Zinc Binding Sites:
The binding sites of Zinc atom in the Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) Glycine
(pdb code 8ihz). This binding sites where shown within
5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) Glycine, PDB code: 8ihz: Zinc binding site 1 out of 1 in 8ihzGo back to Zinc Binding Sites List in 8ihz
Zinc binding site 1 out
of 1 in the Factor Inhibiting Hif-1 Alpha in Complex with (5-(1-(3-(4- Chlorophenyl)Propyl)-1H-1,2,3-Triazol-4-Yl)-3-Hydroxypicolinoyl) Glycine
Mono view Stereo pair view
Reference:
Y.Nakashima,
T.Corner,
X.Zhang,
C.J.Schofield.
A Small-Molecule Fih Inhibitor Binding to A Tyrosine-Flip Pocket Ameliorates Obesity and Mafld To Be Published.
Page generated: Thu Oct 31 07:46:59 2024
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