Zinc in PDB 8hvr: Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter

All present enzymatic activity of Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter:
2.7.7.6;

The structure of Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter (pdb code 8hvr). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter, PDB code: 8hvr:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1402 b:37.0 occ:1.00 SG D:CYS60 2.3 25.1 1.0 SG D:CYS75 2.3 23.9 1.0 SG D:CYS62 2.3 24.9 1.0 SG D:CYS78 2.3 22.6 1.0 CB D:CYS75 3.3 23.9 1.0 CB D:CYS62 3.5 24.9 1.0 CB D:CYS60 3.6 25.1 1.0 N D:CYS62 3.7 24.9 1.0 CB D:CYS78 3.9 22.6 1.0 N D:CYS78 4.0 22.6 1.0 CA D:CYS62 4.1 24.9 1.0 CB D:ARG77 4.2 31.3 1.0 N D:TYR61 4.3 23.7 1.0 CA D:CYS78 4.5 22.6 1.0 C D:CYS60 4.6 25.1 1.0 CA D:CYS75 4.7 23.9 1.0 CA D:CYS60 4.7 25.1 1.0 N D:GLY63 4.8 27.8 1.0 C D:TYR61 4.8 23.7 1.0 C D:CYS62 4.8 24.9 1.0 O D:LYS64 4.8 26.2 1.0 CB D:LYS64 4.8 26.2 1.0 N D:ARG77 4.8 31.3 1.0 C D:ARG77 4.8 31.3 1.0 N D:LYS64 4.8 26.2 1.0 CA D:ARG77 4.8 31.3 1.0 CA D:TYR61 5.0 23.7 1.0

Zinc binding site 2 out of 2 in the Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Afsr-Dependent Transcription Activation Complex with Afss Promoter within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1403 b:16.4 occ:1.00 SG D:CYS969 2.3 12.4 1.0 SG D:CYS972 2.3 11.6 1.0 SG D:CYS962 2.3 16.5 1.0 SG D:CYS886 2.3 27.0 1.0 CB D:CYS972 2.9 11.6 1.0 CB D:CYS969 3.3 12.4 1.0 CB D:CYS886 3.4 27.0 1.0 CB D:CYS962 3.5 16.5 1.0 N D:CYS969 3.9 12.4 1.0 CA D:CYS962 4.0 16.5 1.0 CA D:CYS972 4.1 11.6 1.0 N D:CYS972 4.1 11.6 1.0 CA D:CYS969 4.2 12.4 1.0 N D:CYS886 4.4 27.0 1.0 CA D:CYS886 4.5 27.0 1.0 N D:GLU963 4.5 18.8 1.0 C D:CYS962 4.6 16.5 1.0 CG2 D:THR888 4.7 26.2 1.0 CB D:SER964 4.7 10.5 1.0 C D:CYS969 4.8 12.4 1.0 O D:CYS969 4.9 12.4 1.0 O D:GLU963 5.0 18.8 1.0

Y.Wang, J.Zheng. Structural Basis of Transcription Activation By Streptomyces Antibiotic Regulatory Protein Family Regulator Afsr To Be Published.