Zinc in PDB 8g6d: Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L)

The structure of Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L), PDB code: 8g6d was solved by E.B.Draganova, G.L.Gonzalez Del-Pino, E.E.Heldwein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	94.55 / 3.92
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	109.555, 189.103, 157.096, 90, 100.52, 90
R / Rfree (%)	25.5 / 30.1

The binding sites of Zinc atom in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) (pdb code 8g6d). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 6 binding sites of Zinc where determined in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L), PDB code: 8g6d:
Jump to Zinc binding site number: 1; 2; 3; 4; 5; 6;

Zinc binding site 1 out of 6 in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn401 b:74.5 occ:1.00 NE2 B:HIS225 2.1 65.1 1.0 SG B:CYS106 2.3 72.4 1.0 SG B:CYS125 2.3 63.0 1.0 SG B:CYS122 2.3 56.3 1.0 CD2 B:HIS225 2.9 59.8 1.0 CB B:CYS106 3.0 59.3 1.0 CE1 B:HIS225 3.0 68.0 1.0 CB B:CYS125 3.2 104.6 1.0 CB B:CYS122 3.2 46.6 1.0 N B:CYS125 4.0 83.8 1.0 CG B:HIS225 4.1 55.9 1.0 CA B:CYS125 4.1 95.4 1.0 ND1 B:HIS225 4.1 69.8 1.0 CA B:CYS106 4.5 61.9 1.0 CA B:CYS122 4.7 69.8 1.0 O B:LEU226 4.9 53.8 1.0 C B:CYS122 5.0 99.9 1.0

Zinc binding site 2 out of 6 in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn401 b:121.1 occ:1.00 NE2 D:HIS225 2.1 58.5 1.0 SG D:CYS106 2.3 93.6 1.0 SG D:CYS122 2.3 72.1 1.0 SG D:CYS125 2.3 58.9 1.0 CB D:CYS106 3.0 67.1 1.0 CD2 D:HIS225 3.0 55.2 1.0 CB D:CYS122 3.0 47.5 1.0 CE1 D:HIS225 3.1 62.7 1.0 CB D:CYS125 3.6 80.4 1.0 N D:CYS125 4.0 61.8 1.0 CG D:HIS225 4.2 58.3 1.0 ND1 D:HIS225 4.2 71.2 1.0 CA D:CYS125 4.3 75.6 1.0 CA D:CYS106 4.4 51.9 1.0 CA D:CYS122 4.5 60.9 1.0 OG1 D:THR108 4.7 66.6 1.0 C D:CYS122 4.9 69.8 1.0 C D:CYS106 4.9 57.5 1.0

Zinc binding site 3 out of 6 in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) within 5.0Å range: probe atom residue distance (Å) B Occ F:Zn401 b:100.2 occ:1.00 NE2 F:HIS225 2.1 70.4 1.0 SG F:CYS122 2.3 97.8 1.0 SG F:CYS125 2.3 78.9 1.0 SG F:CYS106 2.3 58.0 1.0 CE1 F:HIS225 3.0 75.6 1.0 CB F:CYS125 3.1 88.2 1.0 CB F:CYS122 3.1 69.4 1.0 CB F:CYS106 3.1 59.6 1.0 CD2 F:HIS225 3.2 51.9 1.0 N F:CYS125 3.8 58.9 1.0 CA F:CYS125 4.0 62.6 1.0 ND1 F:HIS225 4.2 72.7 1.0 CG F:HIS225 4.3 50.5 1.0 CA F:CYS122 4.4 99.1 1.0 O F:CYS122 4.5 62.3 1.0 CA F:CYS106 4.6 74.4 1.0 C F:CYS122 4.6 75.9 1.0 C F:ALA124 4.9 70.7 1.0 CG2 F:THR108 5.0 47.8 1.0

Zinc binding site 4 out of 6 in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) within 5.0Å range: probe atom residue distance (Å) B Occ H:Zn401 b:198.2 occ:1.00 NE2 H:HIS225 2.0 51.5 1.0 SG H:CYS106 2.3 63.7 1.0 SG H:CYS122 2.3 75.8 1.0 SG H:CYS125 2.3 73.9 1.0 CB H:CYS122 2.5 39.5 1.0 CD2 H:HIS225 2.9 42.4 1.0 CB H:CYS106 2.9 62.5 1.0 CE1 H:HIS225 2.9 57.0 1.0 CB H:CYS125 3.7 81.5 1.0 ND1 H:HIS225 3.9 39.5 1.0 CG H:HIS225 4.0 39.5 1.0 CA H:CYS122 4.0 70.8 1.0 CA H:CYS106 4.4 50.6 1.0 N H:CYS125 4.4 67.3 1.0 O H:LEU226 4.5 52.7 1.0 CA H:CYS125 4.6 73.2 1.0 C H:CYS122 4.6 81.0 1.0 OG1 H:THR108 4.6 81.5 1.0 CA H:HIS227 4.8 52.8 1.0 O H:CYS122 4.8 97.1 1.0 C H:CYS106 4.8 50.5 1.0 N H:CYS122 4.8 58.7 1.0

Zinc binding site 5 out of 6 in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) within 5.0Å range: probe atom residue distance (Å) B Occ J:Zn401 b:62.2 occ:1.00 NE2 J:HIS225 2.1 61.2 1.0 SG J:CYS106 2.3 56.8 1.0 SG J:CYS122 2.3 75.2 1.0 SG J:CYS125 2.3 40.4 1.0 CE1 J:HIS225 3.0 55.1 1.0 CD2 J:HIS225 3.0 57.3 1.0 CB J:CYS106 3.1 59.0 1.0 CB J:CYS122 3.3 59.3 1.0 CB J:CYS125 3.4 46.7 1.0 N J:CYS125 3.9 62.9 1.0 ND1 J:HIS225 4.0 61.3 1.0 CG J:HIS225 4.1 54.1 1.0 CA J:CYS125 4.1 64.9 1.0 CG2 J:THR108 4.5 39.5 1.0 CA J:CYS106 4.5 60.8 1.0 CA J:CYS122 4.7 82.0 1.0 C J:ALA124 4.8 56.2 1.0 O J:LEU226 4.9 52.8 1.0 C J:CYS106 4.9 56.0 1.0 CB J:ALA124 5.0 39.5 1.0

Zinc binding site 6 out of 6 in the Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 6 of Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) within 5.0Å range: probe atom residue distance (Å) B Occ L:Zn401 b:159.4 occ:1.00 NE2 L:HIS225 2.1 64.3 1.0 SG L:CYS106 2.3 97.3 1.0 SG L:CYS122 2.3 43.2 1.0 SG L:CYS125 2.3 60.8 1.0 CB L:CYS122 2.9 79.8 1.0 CD2 L:HIS225 2.9 68.4 1.0 CB L:CYS106 3.0 70.5 1.0 CE1 L:HIS225 3.1 71.7 1.0 CB L:CYS125 3.6 78.5 1.0 CG L:HIS225 4.0 64.9 1.0 N L:CYS125 4.0 69.9 1.0 ND1 L:HIS225 4.1 76.3 1.0 CA L:CYS125 4.3 76.2 1.0 CA L:CYS122 4.3 93.1 1.0 CA L:CYS106 4.5 61.0 1.0 OG1 L:THR108 4.7 78.8 1.0 C L:CYS122 4.8 85.8 1.0 C L:CYS106 4.9 63.2 1.0 O L:LEU226 4.9 56.0 1.0 C L:ALA124 5.0 54.0 1.0

E.B.Draganova, G.L.Gonzalez Del-Pino, E.E.Heldwein. Hsv-1 Nuclear Egress Complex (Sup; UL31-R229L) To Be Published.