Zinc in PDB 8fvu: Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A)

All present enzymatic activity of Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A):
3.4.24.83;

The binding sites of Zinc atom in the Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A) (pdb code 8fvu). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 3 binding sites of Zinc where determined in the Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A), PDB code: 8fvu:
Jump to Zinc binding site number: 1; 2; 3;

Zinc binding site 1 out of 3 in the Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1502 b:32.2 occ:1.00 NE2 A:HIS117 2.2 23.2 1.0 SG A:CYS124 2.6 38.6 1.0 CB A:CYS100 2.6 44.2 1.0 SG A:CYS100 3.0 47.6 1.0 CD2 A:HIS117 3.0 22.1 1.0 SG A:CYS97 3.1 600.0 1.0 CE1 A:HIS117 3.2 24.6 1.0 CB A:CYS124 3.3 48.2 1.0 CB A:CYS97 3.8 22.2 1.0 CA A:CYS100 4.1 45.9 1.0 CG A:HIS117 4.2 20.2 1.0 ND1 A:HIS117 4.3 23.3 1.0 N A:CYS100 4.4 38.1 1.0 CD2 A:LEU102 4.6 25.0 1.0 CA A:CYS124 4.6 49.4 1.0 CB A:LEU102 4.7 18.7 1.0 C A:CYS100 4.7 43.5 1.0

Zinc binding site 2 out of 3 in the Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1503 b:40.5 occ:1.00 NE2 A:HIS217 2.2 37.4 1.0 SG A:CYS224 2.6 54.4 1.0 SG A:CYS197 2.6 45.8 1.0 CE1 A:HIS217 3.0 39.5 1.0 CB A:CYS224 3.0 58.5 1.0 CB A:CYS200 3.2 52.0 1.0 CD2 A:HIS217 3.3 33.7 1.0 CB A:CYS197 3.4 49.6 1.0 SG A:CYS200 4.1 73.9 1.0 ND1 A:HIS217 4.1 36.6 1.0 CG A:HIS217 4.3 31.2 1.0 OG A:SER199 4.4 60.5 1.0 O A:PHE221 4.5 45.8 1.0 CA A:CYS200 4.5 55.1 1.0 CA A:CYS224 4.5 57.2 1.0 N A:CYS200 4.5 62.8 1.0 CB A:PHE221 4.6 39.5 1.0 CA A:CYS197 4.9 43.5 1.0

Zinc binding site 3 out of 3 in the Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A) within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn1504 b:60.2 occ:1.00 NE2 A:HIS335 2.2 68.0 1.0 SG A:CYS318 2.5 48.4 1.0 SG A:CYS342 2.6 64.8 1.0 SG A:CYS315 2.6 62.8 1.0 CE1 A:HIS335 3.0 70.3 1.0 CB A:CYS318 3.3 52.9 1.0 CD2 A:HIS335 3.3 80.5 1.0 OG A:SER317 3.3 56.9 1.0 CB A:CYS315 3.4 53.5 1.0 CB A:CYS342 3.4 67.5 1.0 N A:CYS318 4.0 54.5 1.0 C A:SER317 4.1 55.2 1.0 ND1 A:HIS335 4.1 74.3 1.0 CA A:CYS318 4.2 50.8 1.0 CG A:HIS335 4.3 81.7 1.0 O A:SER317 4.4 55.2 1.0 CB A:SER317 4.5 59.9 1.0 CA A:SER317 4.7 59.3 1.0 CA A:CYS342 4.8 66.3 1.0 CA A:CYS315 4.8 46.3 1.0 N A:SER317 4.8 55.4 1.0 CB A:PHE339 5.0 84.3 1.0

R.E.Matico, X.Yu, R.Miller, S.Somani, M.D.Ricketts, N.Kumar, R.A.Steele, Q.Medley, S.Berger, B.Faustin, S.Sharma. Cryo-Em Structure of Human Needle/Naip/NLRC4 (R288A) To Be Published.