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Zinc in PDB 8ftd: Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex

Enzymatic activity of Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex

All present enzymatic activity of Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex:
2.7.7.6;

Other elements in 8ftd:

The structure of Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex also contains other interesting chemical elements:

Magnesium (Mg) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex (pdb code 8ftd). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex, PDB code: 8ftd:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 8ftd

Go back to Zinc Binding Sites List in 8ftd
Zinc binding site 1 out of 2 in the Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1502

b:167.2
occ:1.00
SG J:CYS70 2.3 133.9 1.0
SG J:CYS88 2.3 131.8 1.0
SG J:CYS72 2.3 132.8 1.0
SG J:CYS85 2.3 132.4 1.0
CB J:CYS85 3.0 132.4 1.0
CB J:CYS72 3.6 132.8 1.0
N J:CYS72 3.8 132.8 1.0
CB J:CYS70 3.9 133.9 1.0
CB J:CYS88 3.9 131.8 1.0
N J:CYS88 4.0 131.8 1.0
CA J:CYS72 4.3 132.8 1.0
N J:LEU71 4.4 128.2 1.0
CA J:CYS85 4.5 132.4 1.0
CB J:LYS87 4.5 138.2 1.0
CA J:CYS88 4.5 131.8 1.0
N J:LYS87 4.8 138.2 1.0
CB J:LYS74 4.8 132.8 1.0
C J:LYS87 4.8 138.2 1.0
N J:GLY89 4.9 126.5 1.0
C J:LEU71 4.9 128.2 1.0
CA J:CYS70 4.9 133.9 1.0
CA J:LYS87 4.9 138.2 1.0
C J:CYS72 5.0 132.8 1.0
C J:CYS70 5.0 133.9 1.0
N J:GLY73 5.0 132.9 1.0

Zinc binding site 2 out of 2 in 8ftd

Go back to Zinc Binding Sites List in 8ftd
Zinc binding site 2 out of 2 in the Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Escherichia Coli Ceda in Complex with Transcription Initiation Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Zn1503

b:148.1
occ:1.00
SG J:CYS898 2.3 121.4 1.0
SG J:CYS895 2.3 119.5 1.0
SG J:CYS888 2.3 127.4 1.0
SG J:CYS814 2.3 128.7 1.0
CB J:CYS898 3.0 121.4 1.0
CB J:CYS814 3.3 128.7 1.0
CB J:CYS888 3.4 127.4 1.0
CB J:CYS895 3.5 119.5 1.0
CA J:CYS888 3.7 127.4 1.0
NH2 J:ARG883 3.9 127.3 1.0
N J:CYS898 4.1 121.4 1.0
CA J:CYS898 4.1 121.4 1.0
N J:CYS814 4.1 128.7 1.0
N J:CYS895 4.1 119.5 1.0
N J:ASP889 4.2 133.0 1.0
CA J:CYS814 4.3 128.7 1.0
CA J:CYS895 4.3 119.5 1.0
OG1 J:THR890 4.3 129.9 1.0
C J:CYS888 4.5 127.4 1.0
CG2 J:THR816 4.7 132.8 1.0
O J:CYS895 4.7 119.5 1.0
C J:CYS895 4.8 119.5 1.0
N J:CYS888 4.9 127.4 1.0
CZ J:ARG883 4.9 127.3 1.0
N J:THR890 4.9 129.9 1.0

Reference:

N.Vasilyev, M.M.J.Liu, E.Vitaly, I.Shamovsky, E.Nudler. General Transcription Factor From Escherichia Coli with A Distinct Mechanism of Action Nat.Struct.Mol.Biol. 2024.
ISSN: ESSN 1545-9985
DOI: 10.1038/S41594-023-01154-W
Page generated: Wed Oct 30 20:36:45 2024

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