Zinc in PDB 8el2: Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23

The structure of Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23, PDB code: 8el2 was solved by J.E.Besaw, A.Kuo, T.Morizumi, O.P.Ernst, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.78 / 2.89
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	140.3, 140.3, 202.75, 90, 90, 120
R / Rfree (%)	23.9 / 28.2

The binding sites of Zinc atom in the Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23 (pdb code 8el2). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23, PDB code: 8el2:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23 within 5.0Å range: probe atom residue distance (Å) B Occ L:Zn302 b:147.8 occ:1.00 NZ L:LYS106 2.8 122.8 1.0 CE L:LYS106 3.2 125.8 1.0 OD2 L:ASP87 3.5 97.7 1.0 OD1 L:ASP87 3.9 94.0 1.0 CG L:ASP87 4.1 94.5 1.0 CD L:LYS106 4.5 104.7 1.0 O H:GLY42 4.9 69.7 1.0

Zinc binding site 2 out of 2 in the Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Sars-Cov-2 Rbd Bound to Neutralizing Antibody Fab Ico-HU23 within 5.0Å range: probe atom residue distance (Å) B Occ K:Zn301 b:144.8 occ:1.00 OD2 K:ASP87 3.4 107.8 1.0 OD1 K:ASP87 3.9 92.3 1.0 CG K:ASP87 4.1 97.0 1.0 CD K:LYS106 4.6 100.9 1.0 CE K:LYS106 4.9 112.2 1.0 O I:GLY42 4.9 90.7 1.0

P.Hermet, B.Delache, C.Herate, E.Wolf, G.Kivi, E.Juronen, K.Mumm, E.Zusinaite, D.Kainov, E.Sankovski, K.Virumae, A.Planken, A.Merits, J.E.Besaw, A.W.Yee, T.Morizumi, K.Kim, A.Kuo, A.Berriche, N.Dereuddre-Bosquet, Q.Sconosciuti, T.Naninck, F.Relouzat, M.Ustav, D.Wilson, O.P.Ernst, A.Mannik, R.Legrand, M.Ustav. Broadly Neutralizing Humanized Sars-Cov-2 Antibody Binds to A Conserved Epitope on Spike and Provides Antiviral Protection Through Inhalation-Based Delivery in Non-Human Primates To Be Published.