Zinc in PDB 8d0a: Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab

Enzymatic activity of Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab

All present enzymatic activity of Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab:
3.4.19.12;

Protein crystallography data

The structure of Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab, PDB code: 8d0a was solved by X.Song, J.Butler, C.Li, K.Zhang, D.Zhang, Y.Hao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.11 / 3.19
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 42.229, 71.647, 148.456, 90, 94.31, 90
R / Rfree (%) 24.3 / 29.1

Other elements in 8d0a:

The structure of Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Zinc Binding Sites:

The binding sites of Zinc atom in the Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab (pdb code 8d0a). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab, PDB code: 8d0a:

Zinc binding site 1 out of 1 in 8d0a

Go back to Zinc Binding Sites List in 8d0a
Zinc binding site 1 out of 1 in the Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Crystal Structure of Human USP30 in Complex with A Covalent Inhibitor 829 and A Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Zn602

b:113.3
occ:1.00
 SG A:CYS234 2.4 158.5 1.0
SG A:CYS284 2.4 135.7 1.0
SG A:CYS237 2.5 112.5 1.0
SG A:CYS287 2.7 147.7 1.0
CB A:CYS284 3.2 98.5 1.0
CB A:CYS234 3.3 136.7 1.0
CB A:CYS237 3.5 113.5 1.0
CB A:CYS287 3.6 104.3 1.0
N A:CYS287 3.9 121.2 1.0
N A:CYS237 4.0 133.2 1.0
CA A:CYS237 4.4 125.7 1.0
CA A:CYS287 4.4 110.9 1.0
C A:HIS236 4.6 134.3 1.0
CG2 A:THR306 4.6 105.6 1.0
CA A:CYS284 4.7 104.6 1.0
CB A:HIS236 4.7 121.8 1.0
CA A:CYS234 4.7 101.0 1.0
CB A:ASN286 4.7 106.3 1.0
N A:HIS236 4.8 111.3 1.0
C A:ASN286 4.9 115.2 1.0
CA A:HIS236 4.9 120.2 1.0
C A:CYS234 5.0 122.3 1.0

Reference:

X.Song, J.Butler, Y.Hao. Tbd To Be Published.
Page generated: Wed Oct 30 18:59:58 2024

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