Zinc in PDB 8ac1: Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State

All present enzymatic activity of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State:
2.7.7.6;

The structure of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State (pdb code 8ac1). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State, PDB code: 8ac1:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:364.1 occ:1.00 SG D:CYS85 2.3 344.9 1.0 SG D:CYS72 2.3 341.6 1.0 SG D:CYS70 2.3 337.2 1.0 SG D:CYS88 2.3 335.8 1.0 CB D:CYS70 2.7 337.2 1.0 CB D:CYS85 3.0 344.9 1.0 N D:CYS72 3.7 341.6 1.0 N D:CYS88 3.7 335.8 1.0 CB D:CYS72 3.8 341.6 1.0 CB D:CYS88 3.8 335.8 1.0 N D:GLY73 4.0 333.3 1.0 CA D:CYS70 4.0 337.2 1.0 N D:LEU71 4.0 329.4 1.0 CA D:CYS72 4.1 341.6 1.0 C D:CYS70 4.2 337.2 1.0 N D:LYS74 4.2 325.1 1.0 CA D:CYS88 4.3 335.8 1.0 O D:CYS88 4.4 335.8 1.0 CB D:LYS87 4.4 344.4 1.0 C D:CYS72 4.4 341.6 1.0 CA D:CYS85 4.5 344.9 1.0 CB D:LYS74 4.6 325.1 1.0 N D:LYS87 4.7 344.4 1.0 C D:LEU71 4.7 329.4 1.0 C D:LYS87 4.7 344.4 1.0 CA D:LYS87 4.8 344.4 1.0 C D:CYS88 4.8 335.8 1.0 N D:CYS70 4.9 337.2 1.0 CG D:LYS74 4.9 325.1 1.0 CA D:LEU71 4.9 329.4 1.0 CA D:GLY73 4.9 333.3 1.0 O D:CYS70 4.9 337.2 1.0 C D:CYS85 5.0 344.9 1.0 CA D:LYS74 5.0 325.1 1.0

Zinc binding site 2 out of 2 in the Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Polymerase at U-Rich Pause Bound to Non-Regulatory Rna - Inactive, Open Clamp State within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1503 b:153.3 occ:1.00 SG D:CYS895 2.3 97.9 1.0 SG D:CYS898 2.3 101.0 1.0 SG D:CYS888 2.3 109.5 1.0 SG D:CYS814 2.3 110.7 1.0 CB D:CYS895 2.7 97.9 1.0 CB D:CYS814 3.2 110.7 1.0 CB D:CYS898 3.4 101.0 1.0 N D:CYS814 3.5 110.7 1.0 CB D:CYS888 3.6 109.5 1.0 CG2 D:THR890 3.9 112.7 1.0 CA D:CYS895 3.9 97.9 1.0 N D:CYS895 3.9 97.9 1.0 CA D:CYS814 4.0 110.7 1.0 CG2 D:THR816 4.0 113.8 1.0 CA D:CYS888 4.1 109.5 1.0 NH2 D:ARG883 4.3 105.7 1.0 N D:ASP889 4.6 123.0 1.0 C D:CYS888 4.6 109.5 1.0 C D:ASP813 4.6 108.9 1.0 OD1 D:ASP889 4.7 123.0 1.0 C D:CYS814 4.7 110.7 1.0 CA D:CYS898 4.7 101.0 1.0 CB D:THR816 4.9 113.8 1.0 C D:CYS895 4.9 97.9 1.0 CA D:ASP813 4.9 108.9 1.0 N D:CYS898 4.9 101.0 1.0 N D:GLY815 4.9 115.6 1.0

S.Dey, C.Batisse, J.Shukla, M.W.Webster, M.Takacs, C.Saint-Andre, A.Weixlbaumer. Structural Insights Into Rna-Mediated Transcription Regulation in Bacteria. Mol.Cell V. 82 3885 2022.
ISSN: ISSN 1097-2765
PubMed: 36220101
DOI: 10.1016/J.MOLCEL.2022.09.020