Zinc in PDB 8ac0: Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State

All present enzymatic activity of Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State:
2.7.7.6;

The structure of Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Zinc atom in the Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State (pdb code 8ac0). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State, PDB code: 8ac0:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in the Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1502 b:166.4 occ:1.00 SG D:CYS70 2.3 121.4 1.0 SG D:CYS72 2.3 126.0 1.0 SG D:CYS85 2.3 136.5 1.0 SG D:CYS88 2.3 138.6 1.0 CB D:CYS85 2.6 136.5 1.0 CB D:CYS88 2.7 138.6 1.0 CB D:CYS70 3.1 121.4 1.0 N D:CYS88 3.6 138.6 1.0 CA D:CYS88 3.8 138.6 1.0 CB D:CYS72 3.9 126.0 1.0 CA D:CYS85 4.0 136.5 1.0 N D:CYS72 4.1 126.0 1.0 N D:LYS74 4.2 136.9 1.0 CB D:LYS74 4.2 136.9 1.0 O D:CYS85 4.3 136.5 1.0 N D:GLY73 4.3 127.6 1.0 C D:CYS85 4.4 136.5 1.0 CA D:CYS72 4.4 126.0 1.0 CA D:CYS70 4.4 121.4 1.0 C D:CYS72 4.6 126.0 1.0 N D:LEU71 4.6 116.2 1.0 C D:CYS70 4.7 121.4 1.0 CA D:LYS74 4.8 136.9 1.0 C D:CYS88 4.8 138.6 1.0 N D:TYR75 4.8 127.2 1.0 C D:LYS87 4.8 145.1 1.0 N D:CYS85 4.9 136.5 1.0 N D:GLY89 5.0 128.3 1.0

Zinc binding site 2 out of 2 in the Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Rna Polymerase at U-Rich Pause Bound to Regulatory Rna Putl - Active, Closed Clamp State within 5.0Å range: probe atom residue distance (Å) B Occ D:Zn1503 b:138.6 occ:1.00 SG D:CYS898 2.3 95.6 1.0 SG D:CYS895 2.3 101.3 1.0 SG D:CYS888 2.3 97.1 1.0 SG D:CYS814 2.3 114.5 1.0 NH2 D:ARG883 2.8 105.5 1.0 CB D:CYS814 2.9 114.5 1.0 CB D:CYS888 3.2 97.1 1.0 CB D:CYS898 3.4 95.6 1.0 CB D:CYS895 3.5 101.3 1.0 CA D:CYS888 3.8 97.1 1.0 N D:CYS814 3.8 114.5 1.0 CA D:CYS814 4.0 114.5 1.0 CZ D:ARG883 4.0 105.5 1.0 N D:ASP889 4.1 109.4 1.0 N D:CYS895 4.2 101.3 1.0 CA D:CYS895 4.4 101.3 1.0 C D:CYS888 4.4 97.1 1.0 N D:CYS898 4.5 95.6 1.0 CA D:CYS898 4.5 95.6 1.0 OG1 D:THR816 4.6 116.3 1.0 CG2 D:THR890 4.6 107.3 1.0 NE D:ARG883 4.6 105.5 1.0 OG1 D:THR890 4.7 107.3 1.0 O D:CYS895 4.8 101.3 1.0 C D:CYS895 4.8 101.3 1.0 N D:THR890 4.9 107.3 1.0 C D:CYS814 4.9 114.5 1.0 NH1 D:ARG883 5.0 105.5 1.0

S.Dey, C.Batisse, J.Shukla, M.W.Webster, M.Takacs, C.Saint-Andre, A.Weixlbaumer. Structural Insights Into Rna-Mediated Transcription Regulation in Bacteria. Mol.Cell V. 82 3885 2022.
ISSN: ISSN 1097-2765
PubMed: 36220101
DOI: 10.1016/J.MOLCEL.2022.09.020