Zinc in PDB 7zxe: Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc)

Enzymatic activity of Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc)

All present enzymatic activity of Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc):
2.3.1.48;

Zinc Binding Sites:

The binding sites of Zinc atom in the Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc) (pdb code 7zxe). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 2 binding sites of Zinc where determined in the Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc), PDB code: 7zxe:
Jump to Zinc binding site number: 1; 2;

Zinc binding site 1 out of 2 in 7zxe

Go back to Zinc Binding Sites List in 7zxe
Zinc binding site 1 out of 2 in the Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc) within 5.0Å range:
probe atom residue distance (Å) B Occ
b:Zn501

b:165.6
occ:1.00
NE2 b:HIS313 2.0 141.1 1.0
NE2 b:HIS319 2.0 141.6 1.0
CE1 b:HIS319 2.1 141.6 1.0
SG b:CYS317 2.3 147.7 1.0
SG b:CYS221 2.3 139.8 1.0
CE1 b:HIS313 2.3 141.1 1.0
CB b:CYS221 3.2 139.8 1.0
ND1 b:HIS319 3.3 141.6 1.0
CD2 b:HIS319 3.3 141.6 1.0
CD2 b:HIS313 3.4 141.1 1.0
ND1 b:HIS313 3.6 141.1 1.0
CB b:CYS317 3.8 147.7 1.0
CG b:HIS319 3.9 141.6 1.0
OG b:SER223 3.9 141.2 1.0
CG b:HIS313 4.2 141.1 1.0
CB b:SER223 4.2 141.2 1.0
CG b:PRO189 4.3 142.4 1.0
CA b:CYS221 4.7 139.8 1.0
O b:CYS317 4.7 147.7 1.0
CB b:PRO189 4.7 142.4 1.0
C b:CYS317 4.7 147.7 1.0
CD b:PRO189 4.8 142.4 1.0
CA b:CYS317 4.8 147.7 1.0

Zinc binding site 2 out of 2 in 7zxe

Go back to Zinc Binding Sites List in 7zxe
Zinc binding site 2 out of 2 in the Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc)


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Structure of Snapc Containing Pol II Pre-Initiation Complex Bound to U1 Snrna Promoter (Oc) within 5.0Å range:
probe atom residue distance (Å) B Occ
b:Zn502

b:145.5
occ:1.00
SG b:CYS380 2.3 131.9 1.0
SG b:CYS383 2.3 134.7 1.0
SG b:CYS357 2.3 131.8 1.0
SG b:CYS354 2.3 133.3 1.0
CB b:CYS383 3.2 134.7 1.0
CB b:CYS354 3.2 133.3 1.0
CB b:CYS357 3.5 131.8 1.0
N b:CYS357 3.7 131.8 1.0
CB b:CYS380 3.8 131.9 1.0
O b:CYS357 3.9 131.8 1.0
N b:CYS380 4.1 131.9 1.0
CA b:CYS357 4.1 131.8 1.0
N b:CYS383 4.2 134.7 1.0
CA b:CYS383 4.3 134.7 1.0
CB b:VAL356 4.3 132.6 1.0
C b:CYS357 4.5 131.8 1.0
NE2 c:GLN338 4.5 135.9 1.0
CA b:CYS380 4.5 131.9 1.0
CA b:CYS354 4.6 133.3 1.0
C b:VAL356 4.7 132.6 1.0
CD2 b:TYR360 4.9 133.5 1.0
CG1 b:VAL356 4.9 132.6 1.0
CA b:VAL356 4.9 132.6 1.0

Reference:

S.Rengachari, S.Schilbach, T.Kaliyappan, J.Gouge, K.Zumer, J.Schwarz, H.Urlaub, C.Dienemann, A.Vannini, P.Cramer. Structural Basis of Snapc-Dependent Snrna Transcription Initiation By Rna Polymerase II. Nat.Struct.Mol.Biol. V. 29 1159 2022.
ISSN: ESSN 1545-9985
PubMed: 36424526
DOI: 10.1038/S41594-022-00857-W
Page generated: Sat Apr 8 07:15:16 2023

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