Zinc in PDB 7zol: Cryo-Em Structure of A Crispr Effector in Complex with Regulator

The binding sites of Zinc atom in the Cryo-Em Structure of A Crispr Effector in Complex with Regulator (pdb code 7zol). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 4 binding sites of Zinc where determined in the Cryo-Em Structure of A Crispr Effector in Complex with Regulator, PDB code: 7zol:
Jump to Zinc binding site number: 1; 2; 3; 4;

Zinc binding site 1 out of 4 in the Cryo-Em Structure of A Crispr Effector in Complex with Regulator


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Cryo-Em Structure of A Crispr Effector in Complex with Regulator within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1801 b:18.4 occ:1.00 SG B:CYS1545 2.3 11.4 1.0 SG B:CYS997 2.3 11.4 1.0 SG B:CYS1548 2.3 32.2 1.0 SG B:CYS1515 2.3 11.4 1.0 CB B:CYS1548 3.2 32.2 1.0 CB B:CYS1545 3.2 11.4 1.0 CB B:CYS997 3.5 11.4 1.0 CB B:CYS1515 3.7 11.4 1.0 N B:CYS1545 4.0 11.4 1.0 N B:CYS1548 4.1 32.2 1.0 N B:CYS1515 4.1 11.4 1.0 CA B:CYS1545 4.2 11.4 1.0 CA B:CYS1548 4.2 32.2 1.0 N B:CYS997 4.4 11.4 1.0 CA B:CYS997 4.5 11.4 1.0 CA B:CYS1515 4.5 11.4 1.0 NH1 B:ARG918 4.6 8.4 1.0 CG B:ARG999 4.7 11.4 1.0 C B:CYS1545 4.8 11.4 1.0 O B:CYS1545 4.8 11.4 1.0

Zinc binding site 2 out of 4 in the Cryo-Em Structure of A Crispr Effector in Complex with Regulator


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Cryo-Em Structure of A Crispr Effector in Complex with Regulator within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1802 b:83.3 occ:1.00 SG B:CYS140 2.3 19.9 1.0 SG B:CYS97 2.3 29.1 1.0 SG B:CYS137 2.3 26.0 1.0 SG B:CYS131 2.3 42.5 1.0 CB B:CYS140 3.1 19.9 1.0 CB B:CYS137 3.2 26.0 1.0 CB B:CYS131 3.4 42.5 1.0 CB B:CYS97 3.8 29.1 1.0 N B:CYS137 3.9 26.0 1.0 N B:CYS140 4.0 19.9 1.0 CA B:CYS137 4.1 26.0 1.0 CA B:CYS140 4.2 19.9 1.0 N B:CYS97 4.5 29.1 1.0 O B:CYS97 4.5 29.1 1.0 CA B:CYS97 4.6 29.1 1.0 C B:CYS137 4.8 26.0 1.0 O B:CYS137 4.8 26.0 1.0 C B:CYS97 4.8 29.1 1.0 CA B:CYS131 4.8 42.5 1.0 NH1 B:ARG145 4.9 27.2 1.0

Zinc binding site 3 out of 4 in the Cryo-Em Structure of A Crispr Effector in Complex with Regulator


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Cryo-Em Structure of A Crispr Effector in Complex with Regulator within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1803 b:51.9 occ:1.00 SG B:CYS508 2.3 32.4 1.0 SG B:CYS498 2.3 18.8 1.0 SG B:CYS510 2.3 17.6 1.0 SG B:CYS513 2.3 11.4 1.0 O B:SER509 3.4 23.6 1.0 CB B:CYS508 3.6 32.4 1.0 CB B:CYS513 3.7 11.4 1.0 CB B:CYS498 3.8 18.8 1.0 CB B:CYS510 4.0 17.6 1.0 N B:CYS513 4.3 11.4 1.0 C B:SER509 4.4 23.6 1.0 O B:CYS508 4.5 32.4 1.0 C B:CYS508 4.5 32.4 1.0 CA B:CYS513 4.7 11.4 1.0 CA B:CYS508 4.7 32.4 1.0 CA B:CYS510 5.0 17.6 1.0 NH2 B:ARG487 5.0 13.3 1.0 N B:SER509 5.0 23.6 1.0 CA B:CYS498 5.0 18.8 1.0 N B:CYS510 5.0 17.6 1.0 O B:CYS510 5.0 17.6 1.0

Zinc binding site 4 out of 4 in the Cryo-Em Structure of A Crispr Effector in Complex with Regulator


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Cryo-Em Structure of A Crispr Effector in Complex with Regulator within 5.0Å range: probe atom residue distance (Å) B Occ B:Zn1804 b:23.4 occ:1.00 ND1 B:HIS754 2.1 18.4 1.0 CE1 B:HIS754 2.1 18.4 1.0 SG B:CYS759 2.3 11.4 1.0 SG B:CYS757 2.3 24.0 1.0 SG B:CYS762 2.3 11.4 1.0 CB B:CYS759 3.2 11.4 1.0 CB B:CYS757 3.2 24.0 1.0 CG B:HIS754 3.4 18.4 1.0 NE2 B:HIS754 3.5 18.4 1.0 CB B:CYS762 3.5 11.4 1.0 N B:CYS759 3.9 11.4 1.0 N B:CYS762 4.0 11.4 1.0 CA B:CYS759 4.1 11.4 1.0 CD2 B:HIS754 4.1 18.4 1.0 CA B:CYS762 4.4 11.4 1.0 CB B:HIS754 4.4 18.4 1.0 CA B:CYS757 4.5 24.0 1.0 CA B:HIS754 4.6 18.4 1.0 C B:CYS757 4.7 24.0 1.0 N B:SER758 4.7 16.8 1.0 C B:CYS759 4.7 11.4 1.0 CD B:ARG752 4.7 1.9 1.0 CB B:LEU761 4.8 11.4 1.0 O B:GLU753 4.8 20.3 1.0 C B:LEU761 5.0 11.4 1.0

E.E.Babatunde, T.Davide, B.Bertrand, N.Sergey, M.Alexander, S.Henning, C.N.Dong. Structural Insights Into the Regulation of CAS7-11 By Tpr-Chat To Be Published.