Zinc in PDB 7zjv: Structure of Human USPL1 in Covalent Complex with Deltan-SUMO2/3-Pa Probe

The structure of Structure of Human USPL1 in Covalent Complex with Deltan-SUMO2/3-Pa Probe, PDB code: 7zjv was solved by Z.Zhao, M.Gersch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.80 / 2.40
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	95.708, 95.708, 82.88, 90, 90, 90
R / Rfree (%)	23 / 25.8

The structure of Structure of Human USPL1 in Covalent Complex with Deltan-SUMO2/3-Pa Probe also contains other interesting chemical elements:

Chlorine

(Cl)

5 atoms

The binding sites of Zinc atom in the Structure of Human USPL1 in Covalent Complex with Deltan-SUMO2/3-Pa Probe (pdb code 7zjv). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total only one binding site of Zinc was determined in the Structure of Human USPL1 in Covalent Complex with Deltan-SUMO2/3-Pa Probe, PDB code: 7zjv:

Zinc binding site 1 out of 1 in the Structure of Human USPL1 in Covalent Complex with Deltan-SUMO2/3-Pa Probe


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Structure of Human USPL1 in Covalent Complex with Deltan-SUMO2/3-Pa Probe within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn801 b:128.3 occ:1.00 SG A:CYS400 2.3 144.7 1.0 SG A:CYS364 2.3 191.6 1.0 SG A:CYS361 2.3 126.5 1.0 SG A:CYS397 2.3 133.0 1.0 CB A:CYS397 3.1 118.7 1.0 CB A:CYS361 3.3 130.0 1.0 CB A:CYS400 3.5 140.9 1.0 CB A:CYS364 3.7 171.9 1.0 N A:CYS400 3.9 137.6 1.0 N A:CYS364 3.9 166.1 1.0 CA A:CYS400 4.3 147.4 1.0 CA A:CYS364 4.3 171.7 1.0 CB A:ASN399 4.5 132.1 1.0 CB A:HIS366 4.5 133.3 1.0 C A:CYS364 4.6 177.1 1.0 CA A:CYS397 4.6 116.3 1.0 O A:CYS364 4.6 173.9 1.0 CB A:SER402 4.6 136.4 1.0 C A:ASN399 4.7 142.8 1.0 CA A:CYS361 4.8 130.4 1.0 CB A:GLN363 4.8 152.2 1.0 N A:HIS366 4.8 137.8 1.0 N A:ASN399 4.9 129.6 1.0 CA A:ASN399 4.9 133.3 1.0 C A:CYS400 5.0 149.1 1.0 C A:CYS397 5.0 120.4 1.0 OG A:SER402 5.0 120.1 1.0

Z.Zhao, R.O’Dea, K.Wendrich, N.Kazi, M.Gersch. Native Semisynthesis of Isopeptide-Linked Substrates For Specificity Analysis of Deubiquitinases and Ubl Proteases J.Am.Chem.Soc. 2023.
ISSN: ESSN 1520-5126
DOI: 10.1021/JACS.3C04062