Zinc in PDB 7zhl: Salmonella Enterica RHS1 C-Terminal Toxin Tretu

The structure of Salmonella Enterica RHS1 C-Terminal Toxin Tretu, PDB code: 7zhl was solved by D.Jurenas, M.Rey, J.Chamot-Rooke, L.Terradot, E.Cascales, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.01 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.546, 66.366, 67.7, 90, 90, 90
R / Rfree (%)	19.2 / 22.6

The binding sites of Zinc atom in the Salmonella Enterica RHS1 C-Terminal Toxin Tretu (pdb code 7zhl). This binding sites where shown within 5.0 Angstroms radius around Zinc atom.
In total 5 binding sites of Zinc where determined in the Salmonella Enterica RHS1 C-Terminal Toxin Tretu, PDB code: 7zhl:
Jump to Zinc binding site number: 1; 2; 3; 4; 5;

Zinc binding site 1 out of 5 in the Salmonella Enterica RHS1 C-Terminal Toxin Tretu


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 1 of Salmonella Enterica RHS1 C-Terminal Toxin Tretu within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn201 b:37.2 occ:1.00 NE2 B:HIS32 2.0 34.5 1.0 O B:HOH211 2.0 11.3 1.0 NE2 A:HIS32 2.1 35.9 1.0 O A:HOH322 2.3 23.6 1.0 O A:HOH320 2.7 27.0 1.0 CE1 B:HIS32 2.9 27.9 1.0 CD2 A:HIS32 3.0 26.1 1.0 CD2 B:HIS32 3.0 15.4 1.0 CE1 A:HIS32 3.1 34.2 1.0 ND1 B:HIS32 4.0 27.4 1.0 CG B:HIS32 4.1 24.5 1.0 CG A:HIS32 4.2 24.6 1.0 CG2 B:THR30 4.2 28.2 1.0 ND1 A:HIS32 4.2 35.3 1.0 CD A:LYS71 4.4 26.5 1.0 NE1 A:TRP69 4.5 35.3 1.0 CE3 B:TRP69 4.5 31.6 1.0 CG2 A:THR30 4.6 32.5 1.0 CZ3 B:TRP69 4.7 31.5 1.0 NZ A:LYS71 4.9 45.7 1.0 CB B:THR30 5.0 30.5 1.0

Zinc binding site 2 out of 5 in the Salmonella Enterica RHS1 C-Terminal Toxin Tretu


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 2 of Salmonella Enterica RHS1 C-Terminal Toxin Tretu within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn202 b:63.3 occ:1.00 OE1 A:GLU104 2.2 53.7 1.0 ZN A:ZN203 2.5 99.7 1.0 OE1 A:GLU111 2.8 59.9 1.0 CD A:GLU104 3.5 61.6 1.0 CD A:GLU111 3.8 63.4 1.0 OE2 A:GLU111 4.0 72.8 1.0 CG A:GLU104 4.3 50.4 1.0 OE2 A:GLU104 4.4 60.5 1.0

Zinc binding site 3 out of 5 in the Salmonella Enterica RHS1 C-Terminal Toxin Tretu


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 3 of Salmonella Enterica RHS1 C-Terminal Toxin Tretu within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn203 b:99.7 occ:1.00 OE2 A:GLU111 2.2 72.8 1.0 ZN A:ZN202 2.5 63.3 1.0 OE1 A:GLU111 2.7 59.9 1.0 CD A:GLU111 2.7 63.4 1.0 CG A:GLU111 4.2 51.9 1.0 OE1 A:GLU104 4.4 53.7 1.0

Zinc binding site 4 out of 5 in the Salmonella Enterica RHS1 C-Terminal Toxin Tretu


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 4 of Salmonella Enterica RHS1 C-Terminal Toxin Tretu within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn204 b:124.1 occ:1.00 OD1 A:ASP40 2.0 68.6 1.0 O A:HOH324 2.6 50.2 1.0 CG A:ASP40 2.7 63.7 1.0 OD2 A:ASP40 2.9 68.4 1.0 CB A:ASP40 4.1 50.0 1.0 CG2 A:ILE39 4.7 33.7 1.0 CA A:ASP40 4.8 35.2 1.0

Zinc binding site 5 out of 5 in the Salmonella Enterica RHS1 C-Terminal Toxin Tretu


Mono view


Stereo pair view

A full contact list of Zinc with other atoms in the Zn binding site number 5 of Salmonella Enterica RHS1 C-Terminal Toxin Tretu within 5.0Å range: probe atom residue distance (Å) B Occ A:Zn205 b:73.4 occ:1.00 OE1 A:GLU67 2.1 58.5 1.0 O A:HOH321 2.2 28.7 1.0 O B:HOH213 2.6 43.1 1.0 CD A:GLU67 2.8 52.1 1.0 OE2 A:GLU67 2.9 43.5 1.0 O B:TRP8 3.6 23.7 1.0 CH2 A:TRP69 3.9 41.9 1.0 NH1 B:ARG7 4.0 25.9 1.0 CB B:TRP8 4.0 23.9 1.0 CG A:GLU67 4.2 51.0 1.0 CZ3 A:TRP69 4.4 41.9 1.0 C B:TRP8 4.4 25.4 1.0 CA B:TRP8 4.6 23.3 1.0 N B:TRP8 4.6 18.0 1.0 CZ B:ARG7 4.6 31.3 1.0 CB A:GLU67 4.7 45.4 1.0 CZ2 A:TRP69 4.8 36.9 1.0 NH2 B:ARG7 4.9 28.2 1.0

D.Jurenas, M.Rey, D.Byrne, J.Chamot-Rooke, L.Terradot, E.Cascales. Salmonella Antibacterial Rhs Polymorphic Toxin Inhibits Translation Through Adp-Ribosylation of Ef-Tu P-Loop. Nucleic Acids Res. 2022.
ISSN: ESSN 1362-4962
PubMed: 36484105
DOI: 10.1093/NAR/GKAC1162